Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$153K - $213K *

Drive efficiency by automating internal processes, enhancing productivity across teams. Collaborate with stakeholders to identify bottlenecks, implement AI solutions, and ensure measurable impact on w...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $214K *

Lead the charge in designing and implementing enterprise Finance solutions, optimizing processes, and driving global transformation initiatives through innovative technology and collaboration with sta...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$100K - $170K *

Unlock your potential as a mobile tech lead, guiding teams in delivering innovative apps. Drive best practices in architecture and CI/CD while collaborating with cross-functional teams to align techni...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$200K - $250K *

Join us to architect and lead the development of scalable fintech solutions. As a technical leader, you'll drive innovation, mentor teams, and ensure architectural integrity while shaping the future o...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$146K - $206K *

Unlock potential by leading software projects, collaborating with teams, and ensuring timely delivery while supporting product development and operational excellence in a dynamic environment...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Build innovative technology solutions for Equity Portfolio Management. Collaborate with stakeholders to enhance functionality and maintain high software quality, while leveraging modern practices and...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$146K - $206K *

Join a dynamic team to build secure customer authentication features, enhancing user experiences across B2C and B2B platforms. Collaborate with engineers to develop backend services and APIs, ensuring...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$86K - $144K *

Unlock potential by leading the design and development of scalable generative AI services, ensuring architectural integrity and mentoring teams. Collaborate with cross-functional stakeholders to drive...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$125K - $150K *

Join a team that's redefining pharmacy automation by leading engineers to deliver impactful solutions. Drive team growth, manage processes, and collaborate with cross-functional partners to ensure suc...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$128K - $153K *

Join a team that's shaping the future of technology by delivering impactful software solutions. Collaborate on innovative projects, optimize data operations, and enhance user experiences while support...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$137K - $182K *

Architect and drive AI-powered applications for drug development, focusing on protocol generation and clinical trials. Lead technical direction, mentor engineers, and ensure compliance while fostering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Champion the development of impactful software solutions, collaborating across teams to enhance educational tools. Take ownership of code quality and performance, while mentoring peers and leveraging...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$236K - $296K *

Champion technical excellence by leading full-stack teams in revolutionizing credit card solutions. Collaborate with stakeholders to drive scalable, high-performing initiatives while mentoring enginee...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$199K - $235K *

Champion the development of secure backend services and APIs, enhancing user administration capabilities. Collaborate across teams to ensure reliable, high-quality software while mentoring peers and d...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $200K *

Join a team that's transforming enterprise security insights through innovative reporting and integrations. Collaborate with a passionate community to build features that matter, enhancing user safety...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Information Technology

$186K - $218K *

Elevate operational excellence by engineering reliable Kubernetes solutions that streamline compute orchestration, enhance automation, and drive AI integration for a robust developer experience across...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Accelerate progress at a dynamic engineering team, tackling complex technical challenges while delivering high-quality code. Own architectural decisions and enhance integration across services in a co...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$132K - $251K *

Drive innovation by leading a team in the design and development of next-gen avionics software, ensuring compliance with civil certification standards while managing project scope, schedule, and budge...

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Architect robust CI/CD pipelines and cloud infrastructure while driving innovation in geospatial science. Collaborate on AI architecture and ensure compliance-ready deployments across multi-cloud envi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$171K - $248K *

Lead a dynamic engineering team to enhance infrastructure and networking, driving user-focused product development while fostering collaboration and operational excellence across the organization...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$153K - $213K *

Take ownership of a customer-facing product area, driving strategy and execution. Collaborate cross-functionally to enhance user experience, leverage AI, and achieve key performance metrics while deli...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate our software engineering capabilities by designing and building modern, cloud-native data pipelines. Collaborate with diverse teams to ensure seamless project delivery and advocate for best pr...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$173K - $255K *

Champion the future of data infrastructure by leading a team to deliver scalable, reliable solutions for data access and processing, ensuring high availability and supporting critical business operati...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$225K - $265K *

Drive the development of seamless integrations for security platforms, leading a team to deliver high-quality, reliable products that enhance customer security stacks and ensure compatibility with evo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$103K - $181K *

Shape the future of secure software by developing full-stack applications that support critical government missions. Collaborate with diverse teams to deliver reliable, scalable solutions in dynamic e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.