Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$500K+*

Lead the charge in developing a next-gen AI/ML serving and inference platform. Collaborate with cross-functional teams to architect scalable solutions that empower ML practitioners across diverse doma...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Hospitality & Recreation

$150K - $180K *

Elevate our search capabilities by architecting high-scale solutions, leading multi-quarter transformations, and ensuring operational excellence across a global cloud infrastructure while mentoring em...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$204K - $290K *

Empower the future of fraud prevention by leading cross-functional projects, designing innovative systems, and mentoring engineers. Drive growth while safeguarding users through data-driven insights a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$180K - $220K *

Help us optimize healthcare data processes by designing and managing robust data pipelines. You'll integrate legacy systems into a unified platform, ensuring data quality and operational efficiency in...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$102K - $136K *

Join a team that's transforming healthcare by developing essential tooling and AI capabilities for engineers. This role spans software development, architecture, and collaboration in an Agile environm...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Empower our data platform by designing, building, and operating core capabilities. Collaborate with teams to enhance ingestion, storage, and API functionalities, ensuring scalability and resilience wh...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $155K *

Join a team that's redefining retail technology by leading a high-performing engineering group focused on modernizing and automating store platforms for a global audience, ensuring reliability and sca...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Shape the future of financial operations by owning and modernizing financial systems, automating processes, and collaborating with engineering to streamline integrations for enhanced efficiency and re...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $200K *

Lead complex technical initiatives, ensuring scalable, secure solutions while mentoring engineers and driving high standards across the software development lifecycle in a remote, collaborative enviro...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Media

$112K - $140K *

Transform the future of software development by architecting and enhancing back-end solutions across diverse applications, mentoring engineers, and driving Agile processes to deliver high-quality soft...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$107K - $204K *

Unlock potential by leading embedded software engineering initiatives, optimizing DevSecOps pipelines, and mentoring teams. Collaborate across departments to enhance automation and drive innovation in...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$145K - $225K *

Lead the charge in software development, driving innovation and collaboration across teams. Oversee strategic planning and team development to enhance product quality and efficiency, while fostering a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$118K - $216K *

Reimagine mobile monetization by leveraging AI to build premium user experiences. Drive product innovation and ownership, ensuring reliability for millions of users while expanding into new markets wi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Join a team that's dedicated to solving complex software challenges. As a Sr. Software Engineer, you'll design, build, and maintain robust applications while collaborating across teams to enhance our...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$166K - $230K *

Innovate the borrower experience by leading complex software projects, shaping architecture, and mentoring engineers. Collaborate across teams to deliver high-quality, scalable solutions that enhance...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $160K *

Empower a talented engineering team to develop innovative airgap-native software solutions. Drive product success in National Defense by ensuring seamless integration with UDS, fostering collaboration...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $190K *

Lead the charge in developing innovative software solutions that enhance healthcare delivery. Collaborate with cross-functional teams to design, build, and scale critical systems, ensuring seamless in...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead the development and enhancement of innovative banking solutions, collaborating with cross-functional teams to deliver high-quality software applications while ensuring maintainability and perform...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$195K - $235K *

Drive innovation in autonomous systems by building robust platforms for AI agents, ensuring seamless execution and user-friendly interfaces while tackling complex distributed systems challenges across...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Lead the charge in designing and deploying AI systems that enhance productivity and customer experience across multiple departments, driving innovation and efficiency through advanced AI capabilities...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$96K - $151K *

Join a team that's transforming healthcare by developing analytic products from clinical data. Collaborate in an agile environment to deliver insights that enhance efficacy and drive innovation in the...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $120K *

Lead the charge in quality engineering for critical assessment platforms, driving testing excellence and automation maturity. Collaborate with cross-functional teams to ensure reliability and scalabil...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$140K - $165K *

Empower teams by leading complex, cross-functional programs that enhance cloud infrastructure. Drive execution through ambiguity, ensuring high-impact delivery while collaborating with engineering and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$86K - $119K *

Lead the charge in building and supporting enterprise data solutions that transform business requirements into scalable models, enhancing analytics and reporting capabilities across the organization...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $155K *

Join a team that's shaping the future of data services by designing and implementing robust integration solutions. Leverage your expertise in Ruby on Rails and REST APIs to drive innovative projects a...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.