Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Senior Software Development Engineer - Workforce Integrations
$120K - $145K *
Lead the development of scalable cloud applications while mentoring a team of engineers. Drive collaboration across departments and uphold high standards of software quality and security. Contribute t...
Reposted 3 weeks ago
$165K - $180K *
Transform healthcare solutions by leading the design and development of scalable, high-performance systems. Collaborate with cross-functional teams and mentor junior engineers to drive innovation and...
3 weeks ago
Software Engineer II, Backend (Batch Developer Experience)
$146K - $206K *
Build innovative backend systems to enhance batch development and testing. Collaborate with cross-functional teams to streamline workflows, improve reliability, and support operational excellence in a...
2 weeks ago
$83K - $124K *
Unlock potential by leading the design and implementation of CI/CD pipelines, enhancing software delivery and operational stability for enterprise applications while collaborating with cross-functiona...
Yesterday
$100K - $120K *
Empower quality through engineering excellence and automation. Drive innovation by integrating automated testing into CI/CD pipelines, collaborating with teams to elevate software standards and preven...
3 weeks ago
Senior Program Engineer, IT Services & Cloud Operations
$120K - $150K *
Drive complex federal platform initiatives, enhancing security, compliance, and infrastructure through innovative engineering solutions and cross-functional leadership...
Reposted 3 weeks ago
Senior Program Manager/Engineering Manager
$125K - $225K *
Lead the charge in multidisciplinary engineering and design management for a large-scale industrial infrastructure project, ensuring compliance with technical standards and client expectations through...
Today
Principal AI Software Engineer
$150K - $180K *
Lead the charge in designing and deploying AI systems that enhance productivity and customer experience across multiple departments, driving innovation and efficiency through advanced AI capabilities...
4 days ago
$229K - $258K *
Empower a dynamic engineering team to deliver innovative security tools. Own product development from roadmap to rollout, fostering collaboration and driving results in a fast-paced environment focuse...
3 weeks ago
$169K - $220K *
Accelerate your career by leading a dynamic mobile engineering team focused on delivering innovative iOS and Android experiences, fostering quality and collaboration while driving product growth acros...
Reposted 3 weeks ago
Software Engineer, SRE and Production Engineering - DGX Cloud
$184K - $287K *
Drive the future of AI infrastructure by building automation and tools for large-scale GPU systems. Collaborate with cross-functional teams to enhance production reliability and ensure seamless operat...
1 week ago
$150K - $180K *
Transform the Kubernetes and AI/ML infrastructure landscape by leading cross-team initiatives, defining architecture, and enhancing platform reliability for scalable, secure cloud solutions...
2 weeks ago
Staff Software Engineer - Files Platform
$158K - $248K *
Unlock potential by architecting scalable file management solutions, integrating distributed systems, and ensuring secure access for enterprise customers. Collaborate across teams to enhance data acce...
3 weeks ago
$100K - $120K *
Join a team that's dedicated to building and enhancing robust full-stack solutions. You'll take ownership of features from design to deployment, collaborating with engineers to deliver high-quality, s...
3 days ago
Software Engineer, AI Systems (United States)
$125K - $150K *
Lead the development and operation of AI reasoning systems to enhance safety and efficiency in critical industries. Engage in multi-step LLM pipelines, ensure precision in product output, and work clo...
3 weeks ago
$110K - $130K *
Drive the development of robust data pipelines and architecture to enhance our AI-enabled energy solutions, ensuring reliability and automation while collaborating with product teams to optimize data...
Today
Principal Software Engineer, Agentic Data Platform
$255K - $290K *
Drive the technical vision for a complex database platform, ensuring scalability and performance. Lead architecture decisions, mentor engineers, and collaborate across teams to enhance data infrastruc...
1 week ago
$150K - $225K *
Join us in driving the design and implementation of scalable systems, leading architectural decisions, mentoring engineers, and collaborating cross-functionally to deliver high-quality software soluti...
3 weeks ago
$120K - $145K *
Elevate the performance and reliability of our AI-native platform by managing infrastructure, CI/CD processes, and user experience. Shape tooling to boost developer efficiency and ensure a stable, fas...
Reposted 4 weeks ago
$80K - $95K *
Contribute to the development and maintenance of web applications by coding, testing, and troubleshooting programs. Collaborate with teams to analyze requirements and ensure high-quality, scalable sol...
Today
$180K - $200K *
Shape the future of technology as a senior technical leader, driving complex initiatives and mentoring engineers. Collaborate with cross-functional teams to deliver scalable, secure cloud-native solut...
1 week ago
$110K - $130K *
Join us to empower enterprise customers with innovative sourcing solutions, manage complex RFPs, and collaborate with cross-functional teams to drive procurement success while leveraging cutting-edge...
Reposted 3 weeks ago
Staff Software Engineer - Backend
$125K - $150K *
Champion the development of scalable, cloud-native applications, enhancing data pipelines and integrations. Collaborate with teams to transform raw data into actionable insights, driving improvements...
1 week ago
$120K - $145K *
Transform the Web3 landscape by developing innovative dApps and backend services. Collaborate with cross-functional teams to ensure security, scalability, and seamless user experiences in a dynamic, r...
2 days ago
$85K - $120K *
Unlock innovation as a hands-on Software Engineer, driving Proofs-of-Concept and full software development cycles. Collaborate with senior engineers to explore emerging technologies while ensuring pro...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.