Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Staff Software Engineer, Backend (Search)
$204K - $290K *
Unlock potential by leading a dynamic team to enhance search and recommendation systems, driving consumer engagement and merchant value through innovative technical strategies and collaborative projec...
3 weeks ago
Data Engineering Manager | Home Client Services
$130K - $200K *
Lead a skilled team of data engineers to design and enhance a robust data platform supporting our home services business, driving innovation and efficiency through modern technologies and AI integrati...
3 weeks ago
Senior Staff Forward Deployed Engineer
$152K - $205K *
Lead the charge in architecting AI-driven solutions for enterprise clients, transforming complex data governance challenges into actionable insights. Collaborate with stakeholders to shape product evo...
2 weeks ago
Senior Product Security Engineer
$157K - $184K *
Empower secure software delivery by designing and maintaining robust CI/CD pipelines, enhancing cloud-native product security, and implementing best practices in software supply chain security. Collab...
2 weeks ago
$125K - $150K *
Lead the charge in managing and optimizing cloud infrastructure across multiple platforms. Collaborate with teams to enhance product reliability and streamline operations while ensuring security and c...
2 weeks ago
Senior Infrastructure Engineer
$163K - $224K *
Transform your career by automating and improving infrastructure systems, collaborating with engineering teams, and enhancing operational efficiency as part of a dynamic team focused on self-service s...
Reposted 1 week ago
Senior Interoperability Architect
$120K - $145K *
Lead the charge in developing interoperability specifications for Veteran health information exchange, collaborating with cross-functional teams to enhance standards and ensure compliance with federal...
3 weeks ago
$115K - $156K *
Pioneer innovative maintenance processes and CMMS capabilities, driving global engineering operations. Collaborate with stakeholders to enhance asset management, reliability, and sustainability while...
1 week ago
Team Lead Software Development
$95K - $115K *
Transform the development landscape by leading a team of developers to enhance and maintain application systems, ensuring quality standards and efficient processes while driving innovation and problem...
Reposted 2 days ago
$66K - $106K *
Champion advanced testing and engineering support for healthcare systems, ensuring operational effectiveness and compliance throughout the system lifecycle. Collaborate with cross-functional teams to...
Reposted 1 week ago
$110K - $145K *
Empower security and compliance within Microsoft cloud environments by engineering and managing robust security controls while fostering a proactive approach to risk assessment and improvement for org...
3 weeks ago
Senior Linux System Administrator
$80K - $100K *
Lead the charge in elevating cloud infrastructure through advanced Linux systems administration, mentoring, and project management in a high-growth tech environment...
Reposted 2 weeks ago
Senior Manager, Engineering Recruiting
$110K - $130K *
Lead the charge in engineering recruiting by shaping hiring strategies, developing a high-performing team, and enhancing scalable processes to support growth while personally managing senior leadershi...
2 days ago
$125K - $150K *
Lead the charge in transforming innovative ideas into impactful AI-driven solutions for public health and medical research. Collaborate with diverse teams to develop MVPs that enhance scientific disco...
Today
$110K - $130K *
Transform customer IT service requirements into innovative solutions that enhance loyalty and profitability. Lead technical resources in delivering high-quality financial industry solutions while ensu...
2 weeks ago
Manager, Support Engineering (AMER)
$115K - $194K *
Lead a dynamic Support Engineering team, enhancing customer experiences through AI-driven solutions, mentorship, and scalable processes while fostering a culture of growth and accountability...
2 weeks ago
$130K - $192K *
Join a team that's implementing robust security controls across multiple brands, safeguarding employees and enhancing productivity through automation and secure practices. Collaborate globally while l...
Reposted 3 days ago
Principal Consulting Engineer - HI
$164K - $240K *
Join us to lead innovative AI solutions, guiding complex projects and client engagements while shaping enterprise architecture and MLOps practices. Collaborate with stakeholders to drive successful ou...
Yesterday
$139K - $235K *
Drive your career forward by owning SEC reporting and disclosures, coordinating cross-functional processes, and enhancing the quality and efficiency of external financial reporting as a critical membe...
Reposted 2 weeks ago
Security Engineer (FedRAMP Engineer)
$140K - $155K *
Join a team that's driving security excellence by implementing technical controls and developing procedures for compliance with NIST and FedRAMP. Collaborate with Cloud Service Providers to ensure sec...
4 weeks ago
Manager, Software Engineering (Loans Lifecycle)
$204K - $264K *
Lead the charge in shaping technical strategy and fostering a culture of quality within your team, ensuring operational excellence and collaboration across product development to drive impactful busin...
1 week ago
$90K - $110K *
Lead the charge in optimizing customer operations by enhancing support and service delivery. Drive team performance, improve workflows, and leverage AI to elevate customer experience and satisfaction...
2 weeks ago
$110K - $130K *
Innovate secure network solutions by engineering and supporting robust infrastructure. Collaborate with cross-functional teams to enhance security technologies, ensuring reliable connectivity and comp...
6 days ago
$150K - $200K *
Develop and maintain robust data pipelines and models, collaborating with cross-functional teams to enhance data practices and ensure quality. Drive modernization efforts in data engineering, optimizi...
Yesterday
Director, Enterprise Architecture & Engineering
$150K - $180K *
Invent and lead the future of enterprise architecture and engineering, driving technical decisions and team management in a dynamic environment. Transform complex systems into scalable, secure solutio...
4 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.