Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$180K - $225K *
Pioneer innovative solutions as a Machine Learning Engineer, fine-tuning transformer models and deploying real-time automation pipelines, collaborating with top talents to tackle complex, data-driven...
3 weeks ago
Chief of Staff, Digital & Product
$161K - $242K *
Join a team that's driving strategic initiatives and digital transformation. Collaborate with senior leaders to tackle complex challenges, influence decision-making, and ensure successful execution of...
1 week ago
Global Product Owner Autonomous Coding
$143K - $196K *
Champion innovative solutions in healthcare coding by leading cross-functional teams, optimizing product strategies, and enhancing customer experiences through data-driven insights and agile methodolo...
2 weeks ago
Principal Full Stack Software Engineer - Vancouver, Canada
$172K - $225K *
Champion innovative solutions and elevate our engineering teams' capabilities by mentoring and guiding strategic product developments, enhancing performance, and ensuring customer satisfaction through...
3 weeks ago
Senior AI Engineer/ A2A, Databricks, MCP
$145K - $175K *
Deliver robust AI solutions by designing and implementing core agents for a cutting-edge enterprise platform. Collaborate with cross-functional teams to ensure high-quality, production-ready deploymen...
3 weeks ago
Senior Engineer, AI Product Security
$153K - $166K *
Drive security excellence by partnering with product teams to embed security practices throughout the development lifecycle, focusing on AI features and risk mitigation to protect millions of users gl...
2 weeks ago
Lead Engineer, Merchandise Technology
$125K - $160K *
Shape the future of global merchandising technology by leading engineering efforts, driving modernization, and ensuring high-quality delivery across diverse platforms. Collaborate with teams to implem...
1 week ago
Senior Machine Learning Systems Engineer - Search
$150K - $180K *
Join a team that's at the forefront of machine learning and search innovation. Collaborate with cross-functional teams to develop scalable ML systems that enhance user experiences and drive impactful...
2 weeks ago
$135K - $160K *
Unlock the potential of enterprise systems by leading the design and architecture of innovative Java full-stack solutions integrated with AI. Collaborate with clients to translate technical constraint...
3 weeks ago
Senior Software Engineer, Backend (Lakehouse Infra)
$173K - $255K *
Champion the future of data infrastructure by leading a team to deliver scalable, reliable solutions for data access and processing, ensuring high availability and supporting critical business operati...
1 week ago
Staff Engineer, Cloud Security
$193K - $309K *
Join a dynamic team to enhance cloud security capabilities, leading hands-on initiatives and shaping strategic direction. Collaborate across engineering teams to secure AWS environments and mentor pee...
2 days ago
Public Sector Strategic Account Executive, DoW
$122K - $205K *
Empower the public sector by modernizing software development with AI-driven solutions. Drive strategic initiatives, cultivate executive relationships, and navigate procurement processes to deliver im...
Reposted 2 weeks ago
Senior Product Analytics Engineer
$142K - $186K *
Pioneer a data-driven culture by designing scalable ELT pipelines and analytics models. Collaborate across teams to ensure product data integrity and empower stakeholders with self-service insights, d...
2 weeks ago
Staff / Staff II - Application Security Engineer
$220K - $270K *
Unlock potential by guiding application security strategies across diverse product landscapes. In this senior technical role, you'll influence architecture, mentor teams, and enhance security processe...
3 weeks ago
$145K - $181K *
Champion the growth of the Security Engineering team, driving collaboration across functions to enhance cybersecurity. Utilize your technical expertise and leadership skills to mentor talent, manage s...
3 weeks ago
$135K - $160K *
Join a team that's redefining AI solutions by leveraging your expertise in designing, building, and deploying innovative AI/ML systems. Be instrumental in delivering enterprise-scale projects from inc...
3 weeks ago
Staff Engineer, Full Stack (US, Canada, SF)
$120K - $145K *
The Staff Front-End Engineer at Short Story will play a crucial role in shaping user experience and engineering standards by developing high-quality web applications using NextJS, React-Query, and Tai...
Reposted 3 weeks ago
Technology Consultant, Cybersecurity and AI Security
$125K - $150K *
Develop and execute cybersecurity growth strategies, fostering executive relationships and leading complex pursuits. Leverage expertise to shape solutions and drive account expansion within institutio...
4 weeks ago
$130K - $160K *
Unlock potential by leading mobile app development, shaping user experiences, and driving technical direction in a fast-paced environment. Collaborate with cross-functional teams to deliver intuitive...
1 week ago
Staff Machine Learning Engineer, Platform (MLOPS)
$154K - $226K *
Oversee the end-to-end deployment of ML and AI models, ensuring reliable production capabilities. Manage infrastructure, monitor performance, and drive operational excellence while collaborating acros...
3 weeks ago
$89K - $115K *
Shape innovative software solutions by designing, developing, and maintaining robust applications. Collaborate with cross-functional teams to enhance user experience and optimize application performan...
Reposted 2 days ago
Director, Software Engineering
$150K - $180K *
Innovate by leading software engineering excellence and AI adoption; manage cross-functional teams to develop impactful tech solutions while maintaining hands-on involvement with proof-of-concept proj...
3 weeks ago
$69K - $101K *
Champion the reliability of automated systems by providing expert technical support, troubleshooting complex issues, and collaborating cross-functionally to ensure operational excellence and seamless...
Yesterday
Sr. Software Engineer (Frontend) - Access Management
$120K - $145K *
Redefine the future of SaaS applications by building scalable, high-performance solutions. Collaborate across teams to drive innovation, prioritize security, and enhance user experience while embracin...
Reposted 4 weeks ago
Senior Mobile Software Engineer - Android & iOS
$135K - $160K *
Grow your career with a dynamic frontend engineering team focused on building robust platforms. Collaborate across teams to enhance product features, ensure high-quality deliverables, and drive innova...
6 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.