Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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$110K - $130K *

Shape your career by developing innovative automation solutions for complex material handling challenges. Collaborate with a diverse team to design, engineer, and implement high-performing systems tha...

US-AnywhereRemote

3 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$85K - $100K *

Empower the Cost Planning team by leading cost estimation and reduction initiatives for new technology projects, ensuring alignment between design and purchasing to meet investment targets and enhance...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$175K - $262K *

Drive enterprise application architecture as the Application Architecture Lead, guiding modernization, rationalization, and integration strategies. Collaborate with stakeholders to ensure a coherent a...

US-AnywhereRemote

2 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$115K - $169K *

Drive project success by leading capital initiatives, ensuring design compliance, and managing execution from conception to completion while collaborating with diverse teams to meet project goals and...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$174K - $225K *

Elevate engineering teams by designing, testing, and maintaining real-time software for complex sensor systems. Collaborate on innovative solutions, focusing on Model Based Systems Engineering to ensu...

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$119K - $140K *

Lead the charge in optimizing our enterprise application ecosystem by designing and integrating key systems like Salesforce, NetSuite, and Boomi. Collaborate with cross-functional teams to enhance dat...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate your career by joining an agile team to design and deliver innovative software solutions that drive business success while ensuring security, stability, and scalability across diverse technica...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $190K *

Bring your expertise to lead and develop a dynamic engineering team, driving the delivery of an innovative, API-driven platform that enhances global digital credentialing. Focus on quality, collaborat...

US-AnywhereRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Lead advanced troubleshooting and repair of medical equipment, ensuring customer satisfaction through service excellence. Collaborate with teams, mentor junior engineers, and drive initiatives to enha...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Lead the installation, maintenance, and troubleshooting of complex medical equipment, ensuring exceptional service and customer satisfaction. Collaborate with teams to drive operational excellence and...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Unlock your potential by providing advanced technical support and service excellence for medical equipment. Collaborate with customers and lead a team to ensure optimal performance and satisfaction ac...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$137K - $182K *

Architect and drive AI-powered applications for drug development, focusing on protocol generation and clinical trials. Lead technical direction, mentor engineers, and ensure compliance while fostering...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Lead the charge in advanced electromagnetic warfare analysis, guiding a team of analysts to assess foreign systems and enhance U.S. military operations through innovative intelligence solutions and en...

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Transform the edge software landscape by owning critical components from design to deployment. Collaborate with cross-functional teams to ensure seamless hardware integration and robust field performa...

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Pioneer innovative solutions as a Senior Manager in Deployed Engineering, leading hands-on deployments and building a high-performing team. Collaborate closely with customers and internal teams to dri...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$65K - $126K *

Join a team that's dedicated to optimizing mainframe network systems. Leverage your expertise in planning, installing, and maintaining software while ensuring system performance and reliability. Colla...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Drive innovation by enhancing CI/CD systems for ML models, automating testing and deployment processes. Collaborate with teams to streamline workflows, reduce manual tasks, and ensure reliable model r...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$244K - $279K *

Champion innovative AI solutions by collaborating with diverse teams to design, develop, and deploy cutting-edge AI systems that revolutionize customer engagement and operational efficiency. Grow your...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$244K - $279K *

Develop and support AI software components, driving innovations in design and architecture. Collaborate cross-functionally to enhance products and ensure scalable, responsible AI solutions that delive...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$244K - $279K *

Lead the charge in developing innovative AI solutions that enhance user experience and operational efficiency. Collaborate with cross-functional teams to create scalable AI systems, ensuring high perf...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Join a team that's building innovative, scalable backend systems using modern technologies like AWS and Java. Leverage your expertise in a dynamic environment to enhance and deliver high-quality finan...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $160K *

Drive your career with a role that leads data engineering initiatives, collaborates cross-functionally, and implements innovative solutions to enhance data security and performance for scalable cloud...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by designing and maintaining automation workflows across IT systems and SaaS platforms. Collaborate with teams to develop integrations and optimize processes, enhancing operational ef...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in defining and executing critical technical programs, enhancing research infrastructure while ensuring impactful collaboration across teams. Empower researchers to translate their wor...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Engage in a dynamic role supporting the F-22 Program Office, managing software testing and engineering activities. Collaborate with military stakeholders to enhance testing efficiency and ensure progr...

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.