Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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$125K - $150K *

Unlock potential by enhancing application security across web apps and APIs. Collaborate with engineering teams to assess risks, conduct reviews, and drive secure software practices throughout the dev...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Lead the charge in shaping the technical landscape of digital accessibility. Drive innovation by designing scalable systems that enhance user experience while mentoring engineers and collaborating acr...

US-AnywhereRemote

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$250K - $290K *

Elevate your career by leading a high-performing engineering team, driving strategy and innovation in web3 technologies. Shape the future of decentralized systems while ensuring top-tier security and...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $135K *

Unlock innovative solutions as a Senior Software Engineer, driving modernization efforts for naval systems. Collaborate with cross-functional teams to enhance performance, develop applications, and en...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$140K - $180K *

Champion innovation by developing full-stack web applications using TypeScript. Collaborate in a dynamic, remote-first team to deliver engaging user experiences, streamline operations, and lead techni...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead a talented team in crafting a high-quality, scalable object storage product that enhances the developer experience, balancing technical execution with product thinking to drive meaningful improve...

US-AnywhereRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$164K - $229K *

Unlock potential by creating scalable, fault-tolerant data systems to support ML and analytics workflows, enabling efficient data processing for critical teams at a leading tech company. Collaborate a...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Media

$125K - $150K *

Lead the charge in shaping advanced software architectures that drive secure, scalable solutions across the full system lifecycle, ensuring compliance and strategic alignment with mission objectives a...

3 days ago

  •   15+ years exp.  •   Information Technology

$95K - $115K *

Optimize CI/CD pipelines and improve Azure infrastructure to enhance deployment and observability. Collaborate with teams, addressing performance issues while deploying critical products that elevate...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Empower our engineering team to enhance support for partners through streamlined processes, incident management, and self-service tools, fostering efficient operations while tackling complex technical...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Join a team that's shaping the future of AI by architecting and building intelligent workflows to integrate models and enterprise data into scalable, production-ready solutions that ensure compliance...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in technical direction and agile processes while mentoring a high-performing software engineering team. Your problem-solving skills will drive the development of scalable, secure solut...

US-AnywhereRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$130K - $160K *

Lead the charge in shaping a robust security function, managing a team while enhancing AWS infrastructure, compliance, and application security within a remote-first culture and fast-paced environment...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Innovate software solutions that enhance healthcare accessibility and improve services for patients and providers, while collaborating within a dynamic team to address business and technical challenge...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$166K - $193K *

Lead and mentor a team of engineers while overseeing technical excellence and driving AI innovation in operational systems. Collaborate cross-functionally to deliver impactful features for post-purcha...

US-AnywhereRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Engineer robust web applications by leading full stack development, optimizing backend APIs and creating high-performance front-ends. Collaborate effectively across teams while ensuring scalable archi...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$202K - $253K *

Shape the future of cardiometabolic care by driving backend architecture and cross-functional collaboration. Lead technical direction, mentor engineers, and deliver scalable solutions that enhance mem...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Innovate with us to develop cutting-edge optimization models that enhance operations and customer experience in private aviation. Join a dynamic team where your engineering skills will drive impactful...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$111K - $180K *

Champion innovative software development by collaborating in a dynamic team, leveraging cutting-edge technologies, and delivering high-quality solutions to enhance user experiences and business proces...

US-AnywhereRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$105K - $149K *

Transform your career by driving vulnerability management and enhancing cybersecurity measures. Collaborate with agile teams to assess risks, implement best practices, and ensure robust defenses again...

US-AnywhereRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$315K - $500K+*

Innovate dynamic gameplay systems by leveraging Generative AI to enhance player experiences. Collaborate closely with designers to prototype and integrate AI features, ensuring seamless performance an...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$68K - $175K *

Join a team that's dedicated to building scalable, secure digital solutions. Leverage your expertise in .NET Core, Next.js, and React Native to drive innovation and mentor junior developers while coll...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$83K - $133K *

Lead customer engagement and technical design for critical power projects, ensuring quality and compliance. Collaborate across teams to resolve issues and manage multiple projects, driving successful...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the charge in developing next-gen data platforms, driving strategic insights and AI solutions. Oversee data architecture, governance, and quality, while mentoring a high-performing team to foster...

US-AnywhereRemote

Yesterday

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Optimize onboarding excellence by designing impactful programs that accelerate new sales hires' productivity and ramp times in a high-growth tech environment. Collaborate across teams to ensure practi...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.