Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$106K - $284K *

Champion the design and development of scalable applications, integrating AI and data systems. Lead technical strategy, mentor teams, and ensure operational excellence across the technology stack whil...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$106K - $284K *

Reimagine application development by leading architecture and scaling core systems. Drive AI integration, mentor teams, and ensure operational excellence across full-stack technologies while deliverin...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$106K - $260K *

Shape the future of digital engineering by designing and implementing innovative software solutions. Collaborate with cross-functional teams to enhance system performance and mentor junior developers...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $177K *

Lead a dynamic Managed Services Engineering team to enhance cloud operations, ensuring exceptional service delivery, compliance, and continuous improvement while driving team development and operation...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $185K *

Accelerate progress at the forefront of test automation, driving quality and performance through innovative strategies and frameworks. Collaborate within an agile team to enhance product scalability a...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$128K - $252K *

Lead the charge in building and managing high-performing software engineering teams. Drive innovation, optimize processes, and deliver high-quality applications while fostering a culture of excellence...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $125K *

Advance your career by ensuring optimal database performance and security. Collaborate with cross-functional teams to implement robust architecture, perform upgrades, and support database applications...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$130K - $155K *

Optimize the development and enhancement of communication ecosystems, focusing on document composition and workflow automation. Collaborate in an Agile environment to deliver high-quality solutions th...

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Drive the development and enhancement of AI-enabled AML transaction monitoring solutions, collaborating with cross-functional teams to ensure compliance and operational efficiency in financial crime r...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Join a dynamic team to build and automate security controls across our infrastructure. You'll manage host hardening, vulnerability assessments, and compliance, leveraging AI tools to enhance security...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$186K - $242K *

Empower innovation at a rapidly growing team, leading API architecture and integrations. Collaborate across teams to enhance platform capabilities while mentoring engineers and ensuring system reliabi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Partner with us to bridge technical solutions and customer needs in a dynamic, cross-functional role. Utilize your expertise to drive adoption of AI agents, influencing product roadmaps and enhancing...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $144K *

Lead the charge in designing and implementing advanced building automation systems for critical infrastructure projects, ensuring seamless integration and optimal performance while managing teams and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$125K - $155K *

Join our dynamic team as a Senior Solutions Engineer, where you'll leverage your technical expertise to drive pre-sales activities, engage with clients, and deliver tailored solutions that enhance bus...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Shape the future of cloud-based software delivery by leading a team focused on high-quality, timely execution of client projects. Foster collaboration and efficiency while managing resources and guidi...

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$152K - $287K *

Advance the future of graphics technology by developing cutting-edge AI solutions. Collaborate globally to design and optimize user-mode drivers and APIs, ensuring compatibility across platforms and g...

North Carolina, USRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$112K - $193K *

Help us lead software engineering teams to deliver high-quality, scalable solutions. Collaborate with cross-functional partners to drive architectural design and optimize performance while fostering a...

Raleigh, NCRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$173K - $207K *

Elevate your career by designing and building essential SDKs that empower engineering teams to create reliable, observable distributed systems. Collaborate across teams to enhance developer experience...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Contribute to innovative data solutions by designing and maintaining an enterprise data warehouse, building robust ETL pipelines, and delivering impactful analytics that drive key business decisions...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$122K - $210K *

Lead execution of advanced technology and renewable energy projects. Mentor a team, integrate solutions, and ensure quality throughout the project lifecycle while engaging customers and driving techni...

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$84K - $87K *

Join us as a Data Operations Engineer, where you'll develop and manage data systems for healthcare claims processing. Collaborate with teams to ensure data accuracy and optimize ETL/ELT pipelines whil...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Transform the future of mobile broadcasting by leading technical operations, ensuring show readiness, and delivering exceptional live production experiences while mentoring teams and managing client r...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Media

$70K - $117K *

Unlock potential by leveraging your expertise in structural engineering to ensure the integrity and safety of marine vessels. Collaborate with a dynamic team to support critical naval operations and e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$200K - $240K *

Lead the charge in shaping a robust IAM security strategy across multiple regions, ensuring compliance and operational excellence while driving innovative security solutions that empower business grow...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Innovate noise control solutions for large-scale AI data centers. Lead acoustic studies, model sound propagation, and recommend effective mitigations while collaborating across engineering teams to en...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.