Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Senior System Software Engineer - Datacenter Power Management
$224K - $431K *
Innovate cutting-edge software for data center power management, spanning architecture, firmware, and AI workloads. Drive product lifecycle from design to deployment, enhancing performance and energy...
Today
System Software Engineer - Data Center GPU Compute Diagnostics
$124K - $195K *
Join a team that's developing cutting-edge diagnostic software for next-gen GPUs and AI systems. Collaborate with experts to validate complex hardware and drive innovation in a fast-paced environment...
Reposted yesterday
Engineering Manager, Knowledge Graph Platform
$217K - $303K *
Innovate with us to lead a high-performing engineering team, shaping a scalable AI-powered knowledge graph platform that enhances data quality and drives impactful user experiences across multiple app...
2 weeks ago
Sr. Staff Systems Engineer - 176072
$120K - $180K *
Unlock your potential by leading systems engineering for advanced pharmacy automation solutions. Drive innovation through technical leadership, collaboration, and continuous improvement across complex...
1 week ago
$100K - $110K *
Solve complex production challenges and ensure system stability as a key technical support resource. Collaborate cross-functionally to enhance customer satisfaction through effective incident manageme...
3 weeks ago
Principal Signal Integrity Engineer
$140K - $321K *
Lead the charge in defining signal integrity strategies and architectures for next-gen storage systems, influencing design methodologies and engineering standards across multiple platforms to drive in...
5 days ago
Director, Software Engineering
$150K - $180K *
Lead and inspire a blended team of developers to enhance AI-driven legal automation platforms, ensuring technical excellence, delivery, and collaboration across functions while managing architecture...
2 weeks ago
$125K - $155K *
Pioneer innovative AI and automation solutions, driving technical leadership and collaboration across teams to enhance retail operations and customer experiences through scalable, secure AI technologi...
Yesterday
$95K - $115K *
Optimize enterprise observability and application performance monitoring by leading a team of engineers. Drive Dynatrace platform strategy, establish monitoring standards, and enhance full-stack visib...
Yesterday
Technical Services Engineer (TSE) I
$101K - $135K *
Drive your career forward as a Technical Services Engineer, providing expertise in energy conservation and retro-commissioning for complex projects in higher education and healthcare. Collaborate with...
1 week ago
Senior Principal Structural Engineer - Data Center Infrastructure (FE)
$156K - $281K *
Join a team that's redefining structural engineering for data centers. As a Senior Principal Structural Engineer, you'll ensure the integrity of innovative designs, collaborating across disciplines to...
Today
Sr. Software Engineer - Provider (Remote)
$110K - $130K *
Champion the future of mental healthcare by architecting innovative solutions for Provider Onboarding. Lead a dynamic team to enhance tools and workflows, ensuring seamless integration for users while...
2 weeks ago
Embedded Firmware Design Engineer - 173
$115K - $145K *
Take ownership of developing embedded firmware for advanced networking and telecommunications products, collaborating closely with hardware teams on system integration, debugging, and product validati...
3 weeks ago
$110K - $130K *
Champion seamless technical integrations by leading end-to-end delivery, troubleshooting, and documentation. Collaborate with customer IT teams to ensure compliance and optimize data flows in a dynami...
2 weeks ago
$80K - $95K *
Unlock project success by leading engineering deliverables, budgets, and schedules while coordinating with diverse teams and stakeholders to ensure timely and accurate execution in a collaborative env...
3 weeks ago
Senior Support Engineer - Tooling & Automation
$79K - $109K *
Unlock your potential by providing technical support and guidance for products aimed at combating online child exploitation. Collaborate across teams to enhance workflows and tooling, leveraging emerg...
3 weeks ago
Senior Machine Learning Engineer, Agentic Systems (Active Secret Clearance)
$185K - $230K *
Unlock your potential as a Senior Machine Learning Engineer, driving innovative AI solutions and enhancing performance across complex workflows. Collaborate with diverse teams to shape the future of A...
2 weeks ago
$110K - $130K *
Join our dynamic team to design innovative electrical systems for the biotech and pharma sectors, leveraging your expertise in clean room and laboratory facilities to deliver exceptional engineering s...
4 weeks ago
Member of Technical Staff, AI Researcher (New Stealth Startup)
$250K - $400K *
Shape the future of AI by designing evaluation frameworks and feedback systems that enhance model performance. Collaborate across teams to translate research into scalable solutions, driving impactful...
Today
$110K - $130K *
Elevate your career by developing and deploying cutting-edge generative AI models. Collaborate with cross-functional teams to create scalable solutions, ensuring high-quality code and innovative techn...
2 weeks ago
$110K - $130K *
Innovate and deliver high-quality generative AI solutions, collaborating with cross-functional teams to develop, deploy, and optimize models. Drive productivity through reusable assets and ensure robu...
2 weeks ago
Platform Engineer (ServiceNow)
$110K - $130K *
Pioneer the administration and development of core business systems, focusing on ServiceNow. Collaborate with cross-functional teams to create scalable solutions that enhance operations, service, and...
Reposted today
$95K - $115K *
Optimize engineering excellence by leading teams and managing projects aligned with strategic goals. Foster innovation, ensure compliance, and enhance customer relations while driving improvements in...
3 weeks ago
Program Manager, Onsite Data Collection
$110K - $130K *
Explore the dynamic role of a Program Manager, overseeing end-to-end data collection programs. Drive operational excellence, client satisfaction, and strategic execution in a fast-paced environment, e...
Yesterday
Senior Platform Engineer, MarTech
$145K - $165K *
Lead the charge in enhancing marketing technology platforms to optimize customer engagement and journey orchestration. Collaborate with cross-functional teams to deliver reliable solutions and improve...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.