Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$100K - $110K *

Solve complex production challenges and ensure system stability as a key technical support resource. Collaborate cross-functionally to enhance customer satisfaction through effective incident manageme...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $321K *

Lead the charge in defining signal integrity strategies and architectures for next-gen storage systems, influencing design methodologies and engineering standards across multiple platforms to drive in...

5 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$150K - $180K *

Lead and inspire a blended team of developers to enhance AI-driven legal automation platforms, ensuring technical excellence, delivery, and collaboration across functions while managing architecture...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$125K - $155K *

Pioneer innovative AI and automation solutions, driving technical leadership and collaboration across teams to enhance retail operations and customer experiences through scalable, secure AI technologi...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Optimize enterprise observability and application performance monitoring by leading a team of engineers. Drive Dynatrace platform strategy, establish monitoring standards, and enhance full-stack visib...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$101K - $135K *

Drive your career forward as a Technical Services Engineer, providing expertise in energy conservation and retro-commissioning for complex projects in higher education and healthcare. Collaborate with...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$156K - $281K *

Join a team that's redefining structural engineering for data centers. As a Senior Principal Structural Engineer, you'll ensure the integrity of innovative designs, collaborating across disciplines to...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Consumer Technology

$110K - $130K *

Champion the future of mental healthcare by architecting innovative solutions for Provider Onboarding. Lead a dynamic team to enhance tools and workflows, ensuring seamless integration for users while...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $145K *

Take ownership of developing embedded firmware for advanced networking and telecommunications products, collaborating closely with hardware teams on system integration, debugging, and product validati...

3 weeks ago

  •   8 - 10 years exp.  •   Staffing

$110K - $130K *

Champion seamless technical integrations by leading end-to-end delivery, troubleshooting, and documentation. Collaborate with customer IT teams to ensure compliance and optimize data flows in a dynami...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Unlock project success by leading engineering deliverables, budgets, and schedules while coordinating with diverse teams and stakeholders to ensure timely and accurate execution in a collaborative env...

3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$79K - $109K *

Unlock your potential by providing technical support and guidance for products aimed at combating online child exploitation. Collaborate across teams to enhance workflows and tooling, leveraging emerg...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$185K - $230K *

Unlock your potential as a Senior Machine Learning Engineer, driving innovative AI solutions and enhancing performance across complex workflows. Collaborate with diverse teams to shape the future of A...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Join our dynamic team to design innovative electrical systems for the biotech and pharma sectors, leveraging your expertise in clean room and laboratory facilities to deliver exceptional engineering s...

4 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$250K - $400K *

Shape the future of AI by designing evaluation frameworks and feedback systems that enhance model performance. Collaborate across teams to translate research into scalable solutions, driving impactful...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate your career by developing and deploying cutting-edge generative AI models. Collaborate with cross-functional teams to create scalable solutions, ensuring high-quality code and innovative techn...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Innovate and deliver high-quality generative AI solutions, collaborating with cross-functional teams to develop, deploy, and optimize models. Drive productivity through reusable assets and ensure robu...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Pioneer the administration and development of core business systems, focusing on ServiceNow. Collaborate with cross-functional teams to create scalable solutions that enhance operations, service, and...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Optimize engineering excellence by leading teams and managing projects aligned with strategic goals. Foster innovation, ensure compliance, and enhance customer relations while driving improvements in...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Explore the dynamic role of a Program Manager, overseeing end-to-end data collection programs. Drive operational excellence, client satisfaction, and strategic execution in a fast-paced environment, e...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$145K - $165K *

Lead the charge in enhancing marketing technology platforms to optimize customer engagement and journey orchestration. Collaborate with cross-functional teams to deliver reliable solutions and improve...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $180K *

Drive software engineering excellence by leading multiple teams, enhancing delivery practices, and fostering a culture of innovation. Collaborate with stakeholders to ensure quality and operational re...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$73K - $102K *

Unlock potential by leading the development of LLM-powered applications and agentic systems. Collaborate across teams to design, implement, and maintain innovative software solutions, ensuring high qu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$83K - $95K *

Engineer secure enterprise infrastructure by designing, implementing, and maintaining robust security measures across on-premises and cloud environments, ensuring compliance with industry standards an...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$240K - $330K *

Join a team that's shaping the future of machine learning by leading a high-performing group dedicated to optimizing data pipelines and enhancing perception modeling. Drive innovation and collaboratio...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.