Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$148K - $201K *

Lead the charge in enhancing software-defined networking capabilities by assessing, modernizing, and securing codebases. Collaborate with engineers and stakeholders to ensure robust, maintainable soft...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $160K *

Elevate your career by joining a dynamic team as a Data Engineer, owning end-to-end data systems and driving platform modernization. You'll improve data reliability and work closely with cross-functio...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Join a team that's shaping the future of backend storage solutions on AWS. You'll design, build, and optimize scalable systems, ensuring high performance and reliability while collaborating with cross...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $160K *

Architect robust Kubernetes solutions to enhance cloud infrastructure. Drive multi-cloud initiatives and implement cell-based architecture for scalable, reliable services. Join a team dedicated to bui...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$94K - $176K *

Drive innovation in document processing by leading high-impact projects, shaping architecture, and optimizing performance in a queue-driven pipeline. Collaborate across teams to enhance AI products an...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$153K - $166K *

Join a team that's shaping the future of AI governance in software development. As a Senior Engineer, you'll design policies and tools that ensure safe, effective use of AI coding agents, empowering d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$170K - $200K *

Advance backend solutions and frontend features, collaborating across teams to build scalable systems and AI integrations, driving product growth from conception to execution...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $187K *

Lead the development of innovative software solutions using Python and AWS. Collaborate with cross-functional teams to create scalable applications that leverage AI/ML technologies, ensuring high perf...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$466K - $500K+*

Accelerate progress at the forefront of ML infrastructure, collaborating with cross-functional teams to design and implement user-centric solutions that enhance model development and deployment for di...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$140K - $165K *

Join a dynamic team as you lead the design and development of complex software systems. Drive technical direction, mentor peers, and ensure high-quality, scalable solutions that align with business go...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $160K *

Elevate your career as a Staff Software Engineer, leading full-stack development in a dynamic team. Design, build, and support healthcare applications while ensuring data security and compliance in a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $145K *

Develop innovative full stack applications to enhance legal operations and compliance. Collaborate with cross-functional teams to deliver secure, scalable solutions using modern technologies and cloud...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$108K - $130K *

Build and maintain scalable backend services in a microservices architecture, leveraging modern programming languages and technologies to enhance critical banking domains and support product developme...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Join a team that's building and scaling a data and analytics platform to enhance clinical AI performance. Collaborate with cross-functional teams to create actionable insights and drive improvements i...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$250K - $300K *

Accelerate progress at a forward-thinking company by leading a dynamic engineering team, fostering a culture of excellence while delivering innovative product features and driving technical growth. Co...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $210K *

Collaborate with cross-functional teams to design and deliver full-stack features, enhancing code quality and mentoring junior engineers while owning projects from inception to deployment in a dynamic...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$154K - $260K *

Innovate and drive technical strategy for AI-powered products at scale. Empower teams to build transformative software solutions, oversee complex projects, and deliver exceptional results that reshape...

RemoteRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$208K - $306K *

Join a team that's redefining engineering excellence by leading platform services that enhance software development. Drive innovation, consolidate capabilities, and foster a culture of collaboration t...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$105K - $202K *

Innovate and build AI-native products that automate complex workflows. Collaborate with cross-functional teams to design, develop, and deploy full-stack applications, ensuring reliability and performa...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$148K - $201K *

Empower the development of our open source software solutions while collaborating with engineers and community contributors. Leverage your cloud native expertise to enhance mission outcomes through in...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$155K - $197K *

Innovate as a Tech Lead, driving architectural evolution and engineering execution for a global web platform. Collaborate with cross-functional teams to enhance digital experiences through advanced AI...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$179K - $228K *

Join a team of engineers solving complex networking and security challenges through low-level software development for critical communication systems. Engage in hands-on programming that directly impa...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Champion innovation as a Senior Software Engineer, driving full-stack solutions and leveraging AI tools to enhance IT lifecycle management. Collaborate with a dynamic team to deliver impactful softwar...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Shape the future of quality assurance by leading automated testing initiatives for cloud-based ERP systems, ensuring seamless integration and performance across various business processes and upgrades...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Drive field engineering excellence by installing, maintaining, and troubleshooting cutting-edge hardware systems. Collaborate with teams to enhance product design and ensure reliable operations in dyn...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.