Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$110K - $130K *

Elevate the quality assurance landscape by building robust test automation frameworks, driving efficient testing practices, and partnering with cross-functional teams to ensure excellence in software...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $160K *

Optimize patient-facing and internal tools by delivering seamless integrations and AI-driven features. Take ownership of end-to-end development in a fast-paced telehealth environment focused on men's...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $111K *

Lead cross-functional teams to design and implement resilient infrastructure solutions. Collaborate with diverse stakeholders to ensure timely delivery of high-quality systems, leveraging automation a...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$110K - $125K *

Join a team that's redefining web development by building innovative applications. Leverage your full-stack expertise in JavaScript and Python while managing cloud infrastructure and data pipelines to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Elevate project delivery by managing integrated schedules for data center builds, ensuring timely execution across teams and partners. Drive risk management and governance while building scalable proc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$99K - $120K *

Join our innovative team to architect and deliver cutting-edge IoT systems for special projects. You'll drive initiatives from concept to field pilot, integrating advanced technologies in a dynamic, c...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Technical Services

$105K - $183K *

Join a team that's dedicated to providing exceptional software support for mainframe IMS systems. You'll play a key role in customer service, problem resolution, and migration services, ensuring seaml...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$95K - $115K *

Join a team that's redefining power systems engineering by leading advanced studies in T&D, enhancing software tools, and fostering collaboration across projects to drive innovation and efficiency in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Drive the design and enhancement of corporate security infrastructure, improving automation and maintaining strong security posture in a cloud environment. Collaborate with teams to implement controls...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$118K - $180K *

Join a dynamic team to analyze solar PV energy yield assessments for utility-scale projects. Lead performance modeling and mentor engineers while expanding expertise across various renewable energy te...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$150K - $180K *

Lead a high-performance engineering team, driving strategy and innovation for Corporate Payments services while aligning technology with business goals. Foster collaboration and continuous improvement...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $185K *

Empower engineering teams by designing and implementing security controls that enhance system integrity and reduce risk. Collaborate cross-functionally to create secure-by-default solutions, enabling...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Empower strategic financial decisions by analyzing investments, market opportunities, and capital allocation. Collaborate with C-suite executives to drive growth and optimize resource allocation while...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$182K - $240K *

Pioneer a high-impact Corporate Systems strategy, leading a dedicated Product Management team to transform internal platforms. Drive cross-functional initiatives in Finance, People, and Sales to deliv...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $130K *

Lead dealership implementations by managing go-lives, training teams, and ensuring seamless integrations. Collaborate with stakeholders to optimize workflows and drive adoption, while traveling freque...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$155K - $165K *

Transform the future of IoT connectivity by leading chipset and module enablement, guiding developers through the NB-IoT NTN journey, and optimizing solutions for real-world applications seamlessly...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$90K - $110K *

Transform the future of telephony systems by enhancing CTI software, collaborating with cross-functional teams to deliver innovative solutions that elevate customer experiences in healthcare environme...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$148K - $263K *

Join a team that's dedicated to developing innovative ServiceNow solutions, enhancing system performance, and ensuring compliance with federal security frameworks while collaborating with stakeholders...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $110K *

Empower your career by bridging technical solutions and customer needs in the drive-thru technology space. Collaborate with Sales and Product teams to design and deliver innovative solutions that enha...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$75K - $115K *

Empower your career by developing user-focused documentation for mission-critical systems. Collaborate with engineers and stakeholders to create clear, accessible content that enhances user experience...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform the learning landscape by leading the design and development of innovative educational materials. You'll engage diverse teams to create immersive, high-quality training experiences using cut...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$85K - $111K *

Optimize infrastructure solutions by leading cross-functional teams to design, implement, and support resilient systems. Collaborate with diverse stakeholders to ensure timely delivery and operational...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Engage in a dynamic role overseeing large projects and teams, ensuring successful delivery through effective stakeholder coordination and project management. Contribute to innovative power delivery so...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$116K - $171K *

Elevate customer success by partnering with developers to implement solutions, troubleshoot technical issues, and enhance product features. Your insights will drive improvements across teams, ensuring...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Transportation

$110K - $130K *

Join a team that's dedicated to the seamless integration and testing of advanced combat systems aboard ships. Oversee hardware installation, software delivery, and stage testing to ensure operational...

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.