Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$130K - $179K *

Lead complex engagements and establish strategic relationships while mentoring teams and driving solutions in high-stakes Public Sector environments. Shape account strategy and deliver measurable impa...

RemoteRemote

1 month ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Lead the charge in driving new business acquisition and expanding opportunities across Consumer Goods, Retail, and Travel sectors. Leverage industry expertise to build relationships and position as a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$170K - $190K *

Lead and innovate within UJET's Core Infrastructure team, focusing on cloud-native services. Shape strategies for scalable solutions that empower engineers and optimize the infrastructure for thousand...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $155K *

Drive the design and development of resilient AWS serverless services, collaborating with senior engineers to enhance platform capabilities while ensuring operational excellence and high-quality autom...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Join a team that's shaping the future of cloud infrastructure by managing a vast AWS estate. Drive automation, maintain platform health, and deliver new features while ensuring compliance in a regulat...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$126K - $200K *

Lead technical solutions architecture for HPE storage platforms, guiding partners and sales teams in developing resilient infrastructure solutions. Drive engagement, enablement, and strategic initiati...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$126K - $200K *

Drive your career forward by providing technical leadership and innovative solutions in enterprise networking. Collaborate with partners to enhance sales engagement and architect cutting-edge solution...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $120K *

Lead the charge in transforming legacy messaging solutions to modern Google technologies. Utilize your expertise in Google Workspace migrations and project management to drive successful deployments a...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $188K *

Elevate your career by designing and building innovative data solutions that empower genomic research and analysis. Collaborate with scientists in a fast-paced R&D environment to support impactful dis...

United StatesRemote

Reposted 1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$94K - $179K *

Lead quality initiatives by optimizing test strategies and automation processes. Collaborate with cross-functional teams to ensure high-quality software delivery while mentoring engineers and driving...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$135K - $160K *

Transform observability in AI with strategic vision, driving technical progress across systems and agent telemetry, while enhancing developer experiences and guiding product direction at the intersect...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Join a team that's redefining data architecture by leading innovative modeling and integration initiatives. Collaborate with AI Engineers to create scalable datasets and optimize performance in a mult...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$105K - $115K *

Shape the future of Navy enterprise networks by leveraging your expertise in network engineering, cybersecurity, and Tier III operations. Collaborate with diverse teams to enhance mission-critical inf...

2 weeks ago

  •   8 - 10 years exp.  •   Staffing

$207K - $218K *

Unlock potential by designing and scaling backend systems for high-value financing operations, ensuring safety and reliability while driving revenue and trading activity in a dynamic financial environ...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $160K *

Lead engineering efforts by writing production code and mentoring a team. Drive modernization initiatives through Java microservices while managing performance and growth of engineers. Collaborate wit...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$222K - $314K *

Accelerate progress at a pivotal backend engineering role, enhancing critical systems and data integrity while driving innovation through high-stakes projects within an empowered team focused on scala...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$160K - $185K *

Shape the future of data engineering by leading the architecture and evolution of a robust enterprise data platform, ensuring reliability and integration across analytics, reporting, and AI capabiliti...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Lead the charge in optimizing project management processes for a VHA client team. Utilize your expertise to enhance strategic planning, decision-making, and execution while collaborating with senior s...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$151K - $309K *

Lead the charge in transforming care agent tools, enhancing system reliability and performance. Collaborate with cross-functional teams to design and implement solutions that streamline support proces...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Analyze customer needs and advance technical solutions in cybersecurity, collaborating with sales and product teams to deliver impactful presentations and proposals while ensuring seamless product int...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$105K - $177K *

Elevate your career by mastering Oracle software engineering in a dynamic, remote environment. Collaborate with a skilled team to enhance database performance and support critical applications while d...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$117K - $157K *

Join a team that's transforming enterprise AI solutions through innovative design and deployment. Leverage your expertise to build secure, scalable AI platforms that enhance business processes and dri...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Join a team that's shaping the future of software development by leading projects, mentoring engineers, and architecting innovative solutions that enhance performance and meet business goals in a coll...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Elevate the search experience by designing and evolving a robust backend system that powers millions of searches. Collaborate across teams to enhance scalability, reliability, and maintainability whil...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Champion project delivery by overseeing HV cable testing projects across North America. Ensure alignment with client expectations while managing resources, schedules, and budgets for successful comple...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.