Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$110K - $130K *

Transform product operations by enhancing collaboration across teams and streamlining the launch processes. Utilize data-driven insights and AI to identify bottlenecks and drive efficiency, ensuring s...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$130K - $160K *

Unlock potential by leading mobile app development, shaping user experiences, and driving technical direction in a fast-paced environment. Collaborate with cross-functional teams to deliver intuitive...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$154K - $226K *

Oversee the end-to-end deployment of ML and AI models, ensuring reliable production capabilities. Manage infrastructure, monitor performance, and drive operational excellence while collaborating acros...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by architecting scalable analytics systems and AI-driven workflows that empower decision-making across our enterprise SaaS business, paving the way for innovation and growth in a d...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Technical Services

$80K - $95K *

Drive engineering excellence by managing projects and teams, ensuring timely completion within budget. Design tooling for new products and enhance existing processes while effectively communicating pr...

3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$89K - $115K *

Shape innovative software solutions by designing, developing, and maintaining robust applications. Collaborate with cross-functional teams to enhance user experience and optimize application performan...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $155K *

Lead cross-functional teams to drive enterprise modernization through AI solutions. Oversee complex implementations, ensuring alignment across technical and business stakeholders while delivering meas...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$69K - $101K *

Champion the reliability of automated systems by providing expert technical support, troubleshooting complex issues, and collaborating cross-functionally to ensure operational excellence and seamless...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Grow your career with a dynamic frontend engineering team focused on building robust platforms. Collaborate across teams to enhance product features, ensure high-quality deliverables, and drive innova...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$246K - $339K *

Champion the evolution of our Data Platform by architecting scalable solutions for large-scale data migrations, empowering teams with self-service storage capabilities, and ensuring reliability across...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Consumer Technology

$88K - $154K *

Optimize and integrate the manufacturing process for hazardous materials, taking ownership from design through commissioning. Collaborate with multidisciplinary teams to ensure safety and efficiency i...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Elevate client success by managing complex projects, ensuring timely delivery, and maintaining budget integrity. Collaborate with diverse teams to drive engagement and optimize project outcomes from i...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Empower your career by enhancing our platform's scalability and reliability. As a Senior Platform Engineer, you'll lead infrastructure improvements, optimize performance, and ensure security while col...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Provide expert technical support and solutions to enhance customer success with Mastercam products, collaborating with teams to optimize workflows and drive product improvements in the West region...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Join a team that's focused on optimizing Active Directory and Group Policy management. You'll implement automation, manage Windows Server lifecycles, and enhance operational efficiency through scripti...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$217K - $303K *

Advance the Android Platform by leading technical direction and cross-team initiatives, focusing on client health, developer experience, and app architecture to enhance performance and reliability for...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$120K - $145K *

Join a team that's pioneering the deployment of scalable AI systems, focusing on building robust APIs, optimizing infrastructure, and ensuring reliable operations in a dynamic environment. Drive innov...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Join a dynamic team to lead connectivity projects for leased data centers, ensuring compliance with standards and managing cross-functional collaboration from site assessment to operational handoff. D...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$171K - $190K *

Unlock potential by leading the design and implementation of scalable data platforms. Drive innovation in cloud data architecture and pipeline automation, collaborating across teams to deliver impactf...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $220K *

Innovate high-performance services by collaborating with engineers to design, implement, and optimize scalable systems, ensuring reliability and efficiency in a distributed environment...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $235K *

Engineer innovative AI/ML solutions by collaborating with teams to design, deploy, and manage scalable models. Drive impactful insights through seamless API integration and advanced training resources...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Lead the development and operation of a cutting-edge Security Observability & Data Platform, enhancing endpoint security, threat detection, and incident response while driving innovation in security s...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Empower the future of patient care by leading the development of scalable referral systems. Collaborate with cross-functional teams to design impactful software solutions that enhance partner and pati...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$88K - $154K *

Engineer innovative Electronic Security Systems solutions for diverse clients, guiding projects from concept to construction. Collaborate with teams to ensure compliance with specifications and delive...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$170K - $200K *

Join us to transform operational data into actionable insights through meticulous data modeling, clear metric definitions, and impactful visualizations. Collaborate across teams to ensure accuracy and...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.