Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$170K - $230K *

Join a team that's redefining SoC design by owning subsystem development, integrating third-party IP, and optimizing PPA for next-gen architectures. Contribute across all design stages and drive impac...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Pioneer innovative solutions as a Senior Manager in Deployed Engineering, leading hands-on deployments and building a high-performing team. Collaborate closely with customers and internal teams to dri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$65K - $126K *

Join a team that's dedicated to optimizing mainframe network systems. Leverage your expertise in planning, installing, and maintaining software while ensuring system performance and reliability. Colla...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Drive innovation by enhancing CI/CD systems for ML models, automating testing and deployment processes. Collaborate with teams to streamline workflows, reduce manual tasks, and ensure reliable model r...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$244K - $279K *

Champion innovative AI solutions by collaborating with diverse teams to design, develop, and deploy cutting-edge AI systems that revolutionize customer engagement and operational efficiency. Grow your...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in defining and executing critical technical programs, enhancing research infrastructure while ensuring impactful collaboration across teams. Empower researchers to translate their wor...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$128K - $160K *

Lead the charge in delivering innovative AI and automation solutions, translating complex business needs into technical designs. Collaborate across teams to enhance productivity and drive continuous i...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Innovate the future of architectural strategy by leading technical direction, fostering collaboration across teams, and driving scalable solutions that align with business goals while mentoring senior...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Join a dynamic team to drive technical vision and operational excellence in cloud-native platforms. Lead engineering efforts, champion security practices, and empower talent while ensuring system stab...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Advance healthcare solutions by developing scalable ML systems, collaborating with cross-functional teams, and driving innovative AI methodologies to enhance patient outcomes and optimize operational...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Unlock potential by leading the design and implementation of cutting-edge test automation solutions, leveraging JavaScript and Python to enhance scalability, quality, and speed in the software develop...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$193K - $309K *

Empower the development of innovative features on a high-traffic Orders platform, collaborating across teams to enhance architecture and tooling, ensuring efficient processing for over 1 billion order...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$116K - $165K *

Lead the design and integration of marine electrical systems for commercial and governmental vessels. Ensure compliance with regulatory standards while managing technical responsibilities for shipboar...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$138K - $165K *

Transform the future of pharmacy operations by leading the development of scalable, reliable front-end solutions. Collaborate with cross-functional teams to enhance user experiences and drive technica...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$193K - $285K *

Empower the Security Engineering team by leading the technical vision for platform hardening across global operations, ensuring a secure and resilient delivery network through innovative practices and...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$139K - $203K *

Architect and develop high-performance backend services, leading complex initiatives and driving technical design decisions to enhance Splunk's enterprise observability and security platform while col...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$202K - $257K *

Empower growth by identifying opportunities and aligning technical strategies with customer goals. Lead solution discussions with executives, drive innovation, and mentor teams to enhance knowledge an...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$120K - $145K *

Champion innovative product development in power connectors and cable assemblies. Lead cross-functional teams, drive technical excellence, and mentor engineering talent to deliver high-quality, cost-e...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $128K *

Champion user interface development and API integration for a federal environmental platform, ensuring accessibility compliance and enhancing data access for regulatory consultations. Collaborate with...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$290K - $340K *

Lead and inspire engineering teams to develop cutting-edge web and AI security solutions. Drive strategy, execution, and organizational health while fostering a culture of innovation and accountabilit...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Lead and innovate within a high-impact engineering team, driving automation and transparency in customer assessments. Foster a culture of accountability while collaborating cross-functionally to deliv...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $150K *

Join a team that's engineering innovative cloud solutions, ensuring stability and performance while driving continuous improvement across scalable environments. Your expertise will shape the future of...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$200K - $275K *

Lead and optimize cloud infrastructure for simulation frameworks, driving team performance and technical strategy. Collaborate cross-functionally to enhance validation processes and ensure robust soft...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Transportation

$154K - $260K *

Transform edge AI solutions by leading a talented engineering team. Drive the strategy for embedded systems and machine learning, ensuring impactful deployment of intelligent safety features for real...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Drive innovative data solutions by managing ETL processes and preparing AI datasets. Collaborate in a fast-paced Agile environment to translate complex requirements into efficient data strategies, ens...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.