Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$125K - $150K *

Lead the development of innovative Provider Onboarding solutions, architecting robust systems and mentoring engineers to enhance mental healthcare access. Drive product implementations and build scala...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $160K *

Empower the development of mission-critical applications on the ServiceNow platform, collaborating with stakeholders to deliver scalable solutions while ensuring compliance with federal standards and...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in modernizing SaaS solutions by integrating AI and automation to enhance delivery efficiency, scalability, and customer outcomes while supporting complex migration projects and foster...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Reimagine data governance by shaping a robust framework that empowers teams to define, manage, and optimize data products with clear accountability, streamlined workflows, and effective collaboration...

RemoteRemote

1 month ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Join a team that's shaping the future of data technology, transforming businesses through strategic data solutions. Drive impactful projects, collaborate with industry leaders, and unlock data potenti...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $170K *

Transform backend services and APIs for high-volume interactions, ensuring reliability and performance. Drive platform evolution through hands-on design and implementation, collaborating with cross-fu...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$123K - $159K *

Build core AI platform capabilities that empower teams to develop, run, and scale GenAI applications, collaborating across the tech stack to deliver impactful solutions for millions of users in a fast...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$220K - $340K *

Champion construction delivery excellence across global data center sites, managing GC performance and budgets of $25M+. Lead strategy, negotiate contracts, and represent construction risks to executi...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$152K - $223K *

Drive operational transformation and cloud readiness by leading database modernization initiatives, improving reliability and engineering excellence through automation and best practices while mentori...

RemoteRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$130K - $155K *

Engineer robust data exchange solutions across regions, ensuring compliance and security. Develop scalable backend services and data pipelines while collaborating globally with cross-functional teams...

RemoteRemote

1 month ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $170K *

Join a dynamic eCommerce team to enhance the online booking experience. Lead complex features in a Next.js and TypeScript application, impacting conversion and patient trust across multiple countries...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$172K - $240K *

Join a team that's redefining AI security! As a Principal AI Security Engineer, you'll lead assessments, design controls, and partner with teams to ensure safe AI adoption across the enterprise, drivi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $184K *

Lead the charge in enhancing platform security and infrastructure as a Senior Software Engineer. Utilize your Python expertise and SRE mindset to drive critical improvements, mentor teammates, and ens...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$167K - $230K *

Develop high-performance software for quantum processors, driving architectural decisions, mentoring teams, and tackling complex challenges. Collaborate with interdisciplinary experts to enhance softw...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$60K - $120K *

Unlock potential by deploying and supporting advanced robotic systems in diverse environments. Collaborate with teams, troubleshoot issues, and enhance client experiences through effective communicati...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$250K - $500K+*

Drive innovation by collaborating with hardware teams to enhance tools, evolve compilers, and improve developer experiences, ensuring efficient and effective hardware design processes...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $150K *

Lead the charge in delivering complex integrations for clients, embedding with their teams to build reusable assets against our API. Transform vague requests into actionable plans while enhancing depl...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $137K *

Optimize project outcomes as you manage small to medium-sized initiatives. Collaborate across teams, navigate risks, and ensure timely delivery of quality solutions while enhancing communication and s...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Unlock potential by leading technical vision and mentoring engineers. Drive modernization and collaboration across teams to build resilient, scalable infrastructure while fostering a high-performance...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$85K - $125K *

Accelerate progress at the forefront of mobile development by leveraging AI tools to enhance iOS applications. Collaborate with cross-functional teams to deliver high-quality, customer-centric marketp...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$218K - $256K *

Empower our engineering teams by owning core developer infrastructure tools and systems. Drive strategic initiatives, enhance CI/build processes, and ensure reliability while mentoring engineers and s...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$136K - $170K *

Drive impactful infrastructure solutions by collaborating with engineering teams to resolve blockers, execute migrations, and develop tooling. Leverage your expertise to enhance platform adoption and...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$120K - $193K *

Engage in architecting and designing digital products, leading teams to implement innovative software solutions while ensuring accountability for product success and performance metrics...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$216K - $240K *

Shape the future of grocery technology by leading the modernization of an on-demand ordering platform. Collaborate with cross-functional teams to create scalable, maintainable solutions, enhancing sys...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$95K - $115K *

Build next-gen applications by developing robust RESTful APIs and web apps using modern technologies. Collaborate with a dynamic team to enhance user experiences and drive innovation in eligibility ap...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.