Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$110K - $130K *

Shape the future of product design by transforming concepts into high-fidelity experiences. Collaborate with cross-functional teams to enhance user interactions through innovative prototyping and AI-a...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform enterprise network architecture by leading LAN migration projects, ensuring seamless transitions to Cisco SDA fabric. Collaborate with cross-functional teams to execute plans, manage changes...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Lead customer engagement through technical discovery and deployment, integrating AI solutions while collaborating with Sales, Product, and Engineering teams. Drive implementation efficiency and bridge...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Energy & Utilities

$83K - $125K *

Shape the future of user experience by leading UX design for data analytics products. Collaborate with cross-functional teams to create intuitive interfaces that enhance engineering workflows and driv...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$115K - $150K *

Join a team that's shaping innovative mechanical solutions for prefabricated platforms. Leverage your expertise in HVAC to lead the development and ensure alignment with customer and operational goals...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Empower a talented engineering team to develop innovative airgap-native software solutions. Drive product success in National Defense by ensuring seamless integration with UDS, fostering collaboration...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Lead and develop engineering teams focused on clinical data integration and insights. Drive the direction of data pipelines and ensure impactful, equitable health outcomes through effective collaborat...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Innovate within a dynamic engineering team, driving robust backend solutions for user-centric products while enhancing platform reliability and efficiency across various projects in a collaborative en...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$131K - $205K *

Engage in the design and evaluation of electric power generation projects. Provide technical support and owner’s engineering services, focusing on thermal power systems. Collaborate on project develop...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Technical Services

$120K - $145K *

Elevate security standards by leading bug bounty programs, conducting audits, and enhancing software supply chain security. Collaborate across teams to build innovative tools that protect users and en...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $155K *

Transform your career by designing and scaling a cutting-edge cloud-native data platform. Collaborate with cross-functional teams to deliver robust data services and optimize data pipelines in a dynam...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$250K - $270K *

Lead the charge in enhancing the guest web ordering experience by managing a team of full-stack engineers. Drive product innovation, optimize conversion rates, and ensure engineering excellence across...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$185K - $297K *

Elevate your engineering career by leading test automation and quality architecture for cloud and mobile systems. Shape technical vision, mentor engineers, and drive AI-first automation strategies whi...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Architect solutions to enhance DevOps teams' security by managing pre-sales technical support, conducting product demos, and serving as a subject matter expert in CI/CD integrations and workflows. Eng...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$185K - $220K *

Unlock your potential as a Staff Full-Stack Product Engineer, driving impactful software solutions and collaborating with partners to enhance enterprise deployments. Join us in shaping the future of A...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$166K - $232K *

Lead the evolution of our data platform to enhance analytics and machine learning capabilities. Collaborate cross-functionally to architect robust data solutions that empower teams to leverage insight...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$115K *

Take ownership of innovative cloud security solutions by engineering autonomous AI tools that meet complex requirements, ensuring robust security and efficiency in high-velocity environments. Drive pr...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $145K *

Lead the development and enhancement of modern web applications using Java, Spring, and Angular. Collaborate with cross-functional teams in an Agile environment to deliver reliable solutions while men...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $280K *

Join us to architect and build a cutting-edge web platform, driving marketing innovation through AI agents. Own technical decisions, enhance user experiences, and ensure seamless integration with our...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$205K - $231K *

Join a team that's redefining software supply chain security. As a Staff Software Engineer, you'll lead backend system design, API development, and cross-team collaboration, driving impactful solution...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$224K - $431K *

Join a team that's redefining AI networking by driving innovation in performance and scalability of distributed systems, optimizing data processing for large language models and generative AI workload...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Join a dynamic team to build and optimize healthcare data pipelines, ensuring data quality and compliance while supporting a statewide Health Information Exchange and Health Data Utility initiatives...

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Champion the development of healthcare data pipelines and quality assurance processes. Play a key role in supporting a statewide Health Information Exchange while ensuring data integrity and complianc...

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform healthcare data management by building robust data pipelines and ensuring data quality. Collaborate with clinical teams to optimize data workflows and enhance the Health Information Exchange...

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Unlock potential by building and optimizing healthcare data pipelines, ensuring data quality and compliance within a remote team dedicated to enhancing health information exchange and utility operatio...

6 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.