Discover Senior Principal Systems Engineer Jobs

Welcome to our category for Senior Principal Systems Engineer roles. You'll find a range of opportunities spanning from systems development to technical leadership.

Senior Principal Systems Engineer Roles

As a Senior Principal Systems Engineer, you'll oversee system architecture, guide technical teams, and address the most complex engineering challenges.

Where Your Skills are Valued

Ladders values your high-level analytical, design and leadership skills. Join us, expand your career opportunities and land the job you're aiming for.

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$99K - $120K *

Build innovative building automation systems in a fast-paced, remote environment. Lead design projects while mentoring junior engineers, collaborating with diverse teams to ensure high-quality deliver...

US-AnywhereRemote

2 days ago

  •   5 - 7 years exp.  •   Technical Services

$117K - $235K *

Join a team that's pushing the boundaries of technology by developing innovative software solutions for complex data processing challenges in real-time remote sensing applications...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$272K - $431K *

Join a leading team to architect and develop next-gen Kubernetes platforms, enhancing cloud and on-prem environments with scalable, resilient solutions for AI and computational workloads across large...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$110K - $135K *

Elevate your career as a Senior Software Engineer, leading complex IBM i/RPG development, overseeing projects, mentoring junior staff, and driving innovation in a dynamic healthcare technology environ...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$94K - $179K *

Lead the charge in designing and supporting critical systems, ensuring reliability and compliance while mentoring junior engineers. Your expertise will drive efficient infrastructure solutions with a...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Unlock potential by designing and evolving our interoperability platform for patient data retrieval and compliance. Collaborate with a remote team to tackle complex challenges and leverage AI tools fo...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$142K - $150K *

Join a collaborative team as you take ownership of RTL design tasks, ensuring correctness through simulation and verification. Contribute to timing closure and work with structured design processes to...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$80K - $128K *

Unlock potential by integrating identity platforms with robust security measures. Collaborate within agile teams to design and maintain APIs, ensuring seamless data flow across federal systems while a...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Innovate solutions as a Senior Engineer, leveraging agentic workflows to deliver AI-enhanced features and functionality across production systems, while fostering collaboration and maintaining high-qu...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $130K *

Transform your career with this senior engineering role, where you'll design, integrate, and support advanced energy storage systems for naval applications, ensuring mission success through innovative...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$152K - $241K *

Unlock innovative solutions as you develop advanced system software for next-gen O-RAN infrastructures. Collaborate across hardware, software, and networking groups to enhance performance and efficien...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$159K - $225K *

Drive the design and development of transformative AI platforms, shaping architecture and guiding teams. This senior role demands extensive technical expertise and hands-on involvement to deliver inno...

US-AnywhereRemote

6 days ago

  •   11 - 15 years exp.  •   Information Technology

$159K - $225K *

Accelerate the development of innovative AI platforms that enhance customer engagement and satisfaction. This strategic role combines hands-on engineering and leadership, shaping the future of AI-driv...

US-AnywhereRemote

6 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$159K - $225K *

Lead the charge in building scalable backend systems and APIs for a modern eCommerce platform. Collaborate across teams to enhance services, streamline integrations, and optimize the order fulfillment...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$159K - $225K *

Innovate backend systems for a global eCommerce platform, focusing on API design, service architecture, and system performance. Collaborate with cross-functional teams to enhance integrations and scal...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $225K *

Drive innovation and strategic leadership in wastewater treatment and reuse projects, guiding multidisciplinary teams to deliver sustainable, cutting-edge engineering solutions while fostering client...

US-AnywhereRemote

Reposted 2 days ago

  •   11 - 15 years exp.  •   Energy & Utilities

$176K - $282K *

Elevate government operations by architecting and implementing high-performance cloud platforms, driving AI/ML modernization across federal environments while collaborating with multi-disciplinary tea...

US-AnywhereRemote

2 weeks ago

  •   15+ years exp.  •   Information Technology

$135K - $160K *

Lead the charge in delivering innovative AI solutions by translating complex business challenges into scalable machine learning applications. Collaborate cross-functionally to design architectures and...

US-AnywhereRemote

Reposted today

  •   11 - 15 years exp.  •   Information Technology

$150K - $230K *

Advance the future of AI-native advertising by enhancing developer tools and systems. Collaborate closely with product teams while building scalable infrastructure to drive productivity and innovation...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $160K *

Shape innovative solutions through hands-on development and agentic AI expertise. Collaborate across systems to architect scalable designs for complex government programs while adhering to security pr...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$107K - $195K *

Transform the security landscape by leading the design and implementation of enterprise network security solutions for a private cloud environment, collaborating with international teams to enhance re...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$111K - $148K *

Shape global telecommunications solutions by designing, configuring, and implementing advanced networks. Collaborate with teams to resolve complex issues and enhance service delivery while ensuring cu...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$135K - $216K *

Drive cybersecurity compliance and engineering for mission-critical systems. Collaborate with cross-functional teams to implement new requirements and maintain a robust security posture while managing...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$224K - $356K *

Engage in full-stack OS enablement for next-gen AI supercomputers. Own Windows platform integration while driving Linux support, collaborating on firmware, drivers, and AI applications for seamless cu...

US-AnywhereRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$150K - $200K *

Lead the charge in acquisition modernization initiatives by providing expert guidance within the NEXUS IT Team. Serve as the key liaison bridging operational needs to technical solutions while driving...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What does a Senior Principal Systems Engineer do?question toggle

    A Senior Principal Systems Engineer handles system architecture, leads technical teams, and solves advanced engineering problems. They're often responsible for guiding overall system design and integration.

  • What skills do I need to have for these roles?question toggle

    Skills commonly required include system design, team leadership, analytical thinking and knowledge in systems integration.

  • What industries hire Senior Principal Systems Engineers?question toggle

    Industries like Technology, Aerospace, Defense, Telecommunications, and more require the expertise of Senior Principal Systems Engineers.