Discover Senior Principal Systems Engineer Jobs

Welcome to our category for Senior Principal Systems Engineer roles. You'll find a range of opportunities spanning from systems development to technical leadership.

Senior Principal Systems Engineer Roles

As a Senior Principal Systems Engineer, you'll oversee system architecture, guide technical teams, and address the most complex engineering challenges.

Where Your Skills are Valued

Ladders values your high-level analytical, design and leadership skills. Join us, expand your career opportunities and land the job you're aiming for.

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$140K - $160K *

Lead the quality strategy and test automation efforts across diverse product lines. Oversee a high-performing QA team, ensuring quality standards are met through innovative testing techniques while fo...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$132K - $198K *

Innovate and lead IT enablement projects across Finance, Legal, and HR, ensuring alignment with broader business strategies. Balance direct leadership of high-risk initiatives with coaching for tactic...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$112K - $168K *

Transform customer engagement in the surgical tech field, enhancing client satisfaction and product adoption through strategic management, data analysis, and dynamic relationship building across the M...

US-AnywhereRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $185K *

Oversee transformational data engineering initiatives by managing teams that build effective data systems and architectures to align with strategic business goals, ensuring performance and deadlines a...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $130K *

Discover a transformative role leading the design and development of enterprise reporting and analytics solutions, driving strategic decisions and optimizing data quality in collaboration with cross-f...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $140K *

Join a team that's transforming software solutions by developing high-quality applications. Lead your peers with innovative designs, mentor fellow engineers, and ensure best practices while contributi...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Contribute to the future of data engineering by leading innovative Azure integrations and solutions. Collaborate with multiple teams to design, implement, and optimize enterprise data pipelines, ensur...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Join a team that's redefining education through AI-powered software. Lead the design and implementation of full-stack solutions, driving innovation and quality for key systems used by students and par...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $220K *

Elevate cloud infrastructure as a Senior Staff Cloud DevOps Engineer specializing in AWS and Kubernetes. Drive technical transformations, mentor engineers, and align solutions with business goals for...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $185K *

Explore an impactful role enhancing developer experiences through API strategy, integration lifecycle management, and collaboration across teams, ensuring seamless communication and support for partne...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$180K - $200K *

Accelerate progress at partner success by enabling solution design and integration. Engage with partners to enhance pipelines, drive technical validation, and foster long-term relationships that contr...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $140K *

Innovate cutting-edge software solutions, driving collaboration across teams to transform ideas into production-ready applications while utilizing modern AI-assisted tools to enhance development effic...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $180K *

Join a team that's redefining healthcare legal solutions, where you'll lead complex contract negotiations and provide strategic guidance to executive teams, driving rapid growth and innovation in a dy...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Drive impactful AI solutions as you mentor a team while collaborating across departments to enhance customer engagement, marketing performance, and business intelligence through advanced machine learn...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $215K *

Partner with us to drive global account strategies, enhance customer value, and deliver transformative growth across 10 strategic accounts while influencing cross-functional teams to achieve outstandi...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $289K *

Lead strategic initiatives for hyperscaler partnerships, optimizing execution and driving success. Collaborate with cross-functional teams and manage stakeholders to ensure alignment with business goa...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$99K - $128K *

Shape the future of cloud infrastructure by automating and securing SaaS platforms. Collaborate with cross-functional teams to enhance operational excellence and drive modernization and scalability wi...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $130K *

Lead the charge in transforming clinical workflows through innovative ultrasound solutions, collaborating cross-functionally to identify needs, define product requirements, and drive market success, w...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Champion K-12 events management innovation. Own the product lifecycle for a leading platform, driving strategy and execution with a focus on revenue growth and customer engagement...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$139K - $185K *

Pioneer strategic procurement initiatives as a senior leader, driving global programs, enhancing supplier partnerships, and implementing best practices to elevate procurement as a value creator within...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$90K - $130K *

Pioneer innovative geospatial solutions to enhance interoperability, governance, and analytics for critical DoD missions. Engage with diverse teams to develop and integrate cutting-edge data visualiza...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Technical Services

$110K - $140K *

Reimagine enterprise operational architectures by aligning IT and OT services. Drive governance and design oversight while ensuring cybersecurity and operational efficiencies across contracts and coll...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$214K - $247K *

Empower teams by leading the design and deployment of reliable financial systems. Drive impactful solutions through collaboration, ensuring seamless operations and leveraging AI to enhance efficiency...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$184K - $287K *

Join a team supporting university researchers on cutting-edge AI systems and foundation models. Drive impactful projects in generative AI, multimodal models, and scalable training methods through coll...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$170K - $184K *

Drive operational excellence by leading a global team that harmonizes onshore and offshore resources. Foster cross-cultural collaboration, enhance performance standards, and ensure accountability acro...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What does a Senior Principal Systems Engineer do?question toggle

    A Senior Principal Systems Engineer handles system architecture, leads technical teams, and solves advanced engineering problems. They're often responsible for guiding overall system design and integration.

  • What skills do I need to have for these roles?question toggle

    Skills commonly required include system design, team leadership, analytical thinking and knowledge in systems integration.

  • What industries hire Senior Principal Systems Engineers?question toggle

    Industries like Technology, Aerospace, Defense, Telecommunications, and more require the expertise of Senior Principal Systems Engineers.