Welcome to our category for Senior Principal Systems Engineer roles. You'll find a range of opportunities spanning from systems development to technical leadership.
As a Senior Principal Systems Engineer, you'll oversee system architecture, guide technical teams, and address the most complex engineering challenges.
Ladders values your high-level analytical, design and leadership skills. Join us, expand your career opportunities and land the job you're aiming for.
$75K - $158K *
Lead the charge in performance testing initiatives, planning and executing automated strategies while overseeing a dedicated team. Collaborate with cross-functional partners to ensure quality standard...
3 weeks ago
$75K - $105K *
Join a dynamic engineering team, driving the future of cloud automation and operational reliability. Collaborate across departments to enhance CI/CD processes, ensuring resilience and efficiency in a...
Reposted 3 days ago
Forward Deployed Engineer, Agentic AI
$120K - $140K *
Optimize the deployment of agentic AI solutions, directly engaging with clients to turn AI capabilities into integrated production systems while ensuring strong ROI through effective technical advisor...
Yesterday
Senior Product Manager, Agentic Products
$175K - $225K *
Drive AI innovation for financial advisors by defining product strategy and leading development from concept to launch. Collaborate closely with teams to ensure alignment and enhance advisor efficienc...
Reposted today
Computer Systems Validation Engineer
$150K - $178K *
Pioneer a comprehensive Computer System Validation strategy across GxP systems. Collaborate with Quality and IT to drive compliance and data integrity while enhancing efficiency in validation processe...
Today
Lead Warehouse Design Engineer
$95K - $115K *
Elevate operational efficiency by leading design and implementation of advanced warehouse systems, encompassing layout, material handling, and automation workflows to optimize logistics and enhance pr...
1 week ago
Lead Warehouse Design Engineer
$95K - $115K *
Unlock potential by leading warehouse design projects, managing engineering activities, and collaborating with teams to optimize material flow and layouts for enhanced efficiency. Ensure successful im...
1 week ago
$110K - $130K *
Join a team that's driving the efficient execution of product roadmaps through impactful coordination across Data Products & Analytics and Engineering. Lead by establishing epic quality and enhancing...
2 days ago
$90K - $130K *
Partner with us to engineer secure, resilient infrastructure across cloud-native and edge environments. You'll ensure operational excellence, mitigate risks, and enhance deployment practices while col...
4 weeks ago
Lead Platform Engineer, HP Nonstop and Infrastructure Platforms
$122K - $207K *
Join a team that's dedicated to designing and optimizing resilient infrastructure platforms supporting critical applications. Collaborate closely with cross-functional teams to enhance performance, re...
5 days ago
Senior Tax Analyst- Strategy & Incentives
$100K - $120K *
Join a dynamic team to oversee and optimize multi-state tax incentive strategies, driving operational efficiencies and fostering collaboration across departments to support strategic growth and compli...
3 days ago
$115K - $155K *
Transform the customer onboarding experience in local government with engineer-led implementations. Collaborate on technical challenges, automate key processes, and ensure data integrity while buildin...
1 week ago
$83K - $160K *
Lead the charge in managing multiple projects for insurance clients, ensuring timely delivery and quality engagement. Collaborate across teams, report on progress, and drive best practices while mento...
Yesterday
Senior Software Engineer, ClearCheck
$150K - $180K *
Empower the future of radiation oncology software by leading the design, development, and maintenance of cutting-edge .NET applications, collaborating closely with remote engineering teams to enhance...
1 week ago
Director, Security Architecture
$190K - $240K *
Unlock potential by leading the evolution of cybersecurity architecture for a secure enterprise. Drive innovation while ensuring compliance with federal regulations and aligning with Zero Trust princi...
2 days ago
$150K - $180K *
Transform healthcare technology by leading an internal engineering team. Oversee the transition of software ownership, manage vendor relationships, and drive AI strategy ensuring patient data privacy...
1 week ago
$120K - $145K *
Unlock your potential as a key contributor in developing innovative, data-driven software solutions for biopharmaceutical processes, enhancing digital transformation efforts through cutting-edge techn...
Reposted yesterday
Program Manager (USMC - WRI ASTRO)
$100K - $120K *
Oversee the comprehensive management of the West Region Infrastructure LMR System, ensuring operational excellence, budget adherence, and proactive collaboration with cross-functional teams to meet Do...
1 week ago
$135K - $160K *
Lead the design and implementation of high-volume transaction systems, focusing on wallet and lifecycle management, cross-chain integrations, and end-to-end engineering, ensuring high reliability and...
1 week ago
Senior Site Reliability Engineer - CLO
$152K - $205K *
Pioneer the development of scalable microservices and AI-enabled tooling, enhancing software delivery experiences. Collaborate with teams to design resilient systems and monitor operational excellence...
1 week ago
$190K - $210K *
Transform the architecture of data solutions for a leading data platform. Collaborate with product and engineering teams to enhance data models, ensure integrity, and coach stakeholders across the org...
Reposted 1 week ago
Sr. Epic Data Acquisition Analyst
$80K - $100K *
Join a team that's shaping the future of healthcare data integration. Lead the technical aspects of client Epic data acquisition, ensuring seamless extraction and delivery of critical information whil...
1 week ago
Sr. Program Analyst - Transformation
$125K - $160K *
Lead the charge in driving operational excellence and transformation by translating business needs into actionable requirements, managing delivery workflows, and enhancing the Revenue Intelligence por...
4 days ago
Associate Director, Full-stack Forward Deployed Engineer
$143K - $273K *
Pioneer the next wave of enterprise AI transformation by leading full-stack engineering teams to create innovative software solutions, integrating advanced language models, and delivering tangible bus...
Yesterday
$100K - $120K *
Empower a dynamic team to lead analytical and programmatic support for key digital health initiatives within federal health agencies. Drive project success through data analysis, stakeholder engagemen...
2 weeks ago
What does a Senior Principal Systems Engineer do?
A Senior Principal Systems Engineer handles system architecture, leads technical teams, and solves advanced engineering problems. They're often responsible for guiding overall system design and integration.
What skills do I need to have for these roles?
Skills commonly required include system design, team leadership, analytical thinking and knowledge in systems integration.
What industries hire Senior Principal Systems Engineers?
Industries like Technology, Aerospace, Defense, Telecommunications, and more require the expertise of Senior Principal Systems Engineers.