Discover Senior Principal Systems Engineer Jobs

Welcome to our category for Senior Principal Systems Engineer roles. You'll find a range of opportunities spanning from systems development to technical leadership.

Senior Principal Systems Engineer Roles

As a Senior Principal Systems Engineer, you'll oversee system architecture, guide technical teams, and address the most complex engineering challenges.

Where Your Skills are Valued

Ladders values your high-level analytical, design and leadership skills. Join us, expand your career opportunities and land the job you're aiming for.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$107K - $204K *

Build and deploy machine learning frameworks for turbine component design, collaborating with the AI/ML team to enhance processes and communicate insights effectively to stakeholders. Drive innovation...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$68K - $131K *

Join a dynamic team to conduct jurisdiction and classification assessments for exports/imports, ensuring compliance with government regulations. Collaborate across functions and enhance regulatory kno...

US-AnywhereRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$184K - $356K *

Unlock potential by partnering with industry leaders to deliver innovative AI solutions leveraging advanced GPU technology, while driving transformative applications within the energy sector...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$130K - $180K *

Transform enterprise-scale AI solutions by enhancing Generative AI applications. Drive experimentation with LLMs and multimodal technologies to create impactful features that serve millions of users i...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $180K *

Drive AI innovation by leading the design of scalable enterprise applications, collaborating with stakeholders to align technical solutions with business goals, and establishing engineering standards...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $160K *

Lead and develop a high-performing engineering team, collaborating across departments to drive innovative solutions and optimize business outcomes while fostering a strong engineering culture...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $200K *

Unlock growth as you lead U.S. revenue strategies, drive client expansion, and build a results-oriented sales team in the evolving cybersecurity landscape, engaging executive stakeholders to maximize...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$112K - $179K *

Lead the charge in optimizing API gateway solutions to support national security systems, ensuring robust integration and maintenance while collaborating with diverse teams to enhance functionality an...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$148K - $198K *

Help us elevate our product line by developing intuitive interfaces and robust services as a Senior Full Stack Engineer. Join a collaborative team focused on innovation and enhancing customer experien...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$105K - $155K *

Unlock potential by joining the Cloud Forensics team to develop software that enhances digital investigations. Utilize reverse engineering and innovative techniques to recover critical internet data f...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$200K - $250K *

Join a team that's driving innovation in electrical design for modular power solutions, ensuring speed-to-power for cutting-edge data centers. Collaborate with vendors and streamline processes to enha...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $150K *

Reimagine Regulatory Affairs by leading complex outsourcing programs and driving client success. Utilize deep expertise in strategy and operations to manage projects, mentor teams, and deliver tailore...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$89K - $148K *

Drive project success by leading cross-functional teams and managing workflows. Utilize advanced tools and methodologies to maintain compliance and achieve milestones in a remote role, ensuring high s...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$90K - $130K *

Elevate your project management career by leading a strategic platform within investor client coverage, enhancing client engagement and driving technology integration across CBRE's commercial real est...

US-AnywhereRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$120K - $150K *

Lead the charge in hands-on technical development, guiding teams through complex challenges and architecting scalable solutions. Engage with stakeholders to shape product features and push the boundar...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $120K *

Contribute to quality assurance and engineering efforts, enhancing product development and compliance through statistical analysis, risk management, and cross-functional collaboration in a regulated e...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$97K - $156K *

Support the optimization of HRIS systems like Workday through process improvements and enhancements. Collaborate across departments to ensure a seamless user experience, system integrity, and efficien...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$127K - $180K *

Lead the charge in developing and maintaining automation tools for spacecraft operations, collaborating with cross-functional teams to enhance satellite mission effectiveness and ensuring high-perform...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$157K - $184K *

Join a pioneering team dedicated to securing software supply chains and cloud-native environments. Leverage your technical expertise in CI/CD, Kubernetes, and industry security frameworks to drive inn...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$200K - $300K *

Join a team that's shaping technological innovation and strategy across the enterprise. You will collaborate with senior leaders, mentor engineers, and advance the adoption of cutting-edge technologie...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$149K - $185K *

Transform customer engagement through strategic field marketing. Lead event planning and execution for impactful customer programs, driving measurable outcomes and fostering cross-functional collabora...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Launch your career as a Portfolio Analyst supporting high-impact government travel operations. Drive efficiencies, ensure regulatory compliance, and enhance program management while collaborating with...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $160K *

Join a team that's building innovative AI solutions to transform healthcare, focusing on designing a Drug/Drug Interaction Smart Connector using LangChain and LangGraph while ensuring data accuracy an...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $285K *

Lead high-impact product initiatives, driving strategy and execution across cross-functional teams. Collaborate to shape AI and data-focused products, delivering measurable customer value while mainta...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$219K - $285K *

Innovate digital strategies in R&D to enhance efficiency and value creation. Collaborate with cross-functional teams, drive operational excellence, and establish a culture of continuous improvement fo...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Senior Principal Systems Engineer do?question toggle

    A Senior Principal Systems Engineer handles system architecture, leads technical teams, and solves advanced engineering problems. They're often responsible for guiding overall system design and integration.

  • What skills do I need to have for these roles?question toggle

    Skills commonly required include system design, team leadership, analytical thinking and knowledge in systems integration.

  • What industries hire Senior Principal Systems Engineers?question toggle

    Industries like Technology, Aerospace, Defense, Telecommunications, and more require the expertise of Senior Principal Systems Engineers.