Discover Senior Principal Systems Engineer Jobs

Welcome to our category for Senior Principal Systems Engineer roles. You'll find a range of opportunities spanning from systems development to technical leadership.

Senior Principal Systems Engineer Roles

As a Senior Principal Systems Engineer, you'll oversee system architecture, guide technical teams, and address the most complex engineering challenges.

Where Your Skills are Valued

Ladders values your high-level analytical, design and leadership skills. Join us, expand your career opportunities and land the job you're aiming for.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$105K - $165K *

Unlock potential by leading infrastructure strategies and solutions that enhance system performance, security, and scalability. Collaborate cross-functionally to implement innovative technology while...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $130K *

Unlock your potential as a Senior Software Engineer II by architecting and implementing robust cloud infrastructure. Collaborate across teams to enhance automation, mentor peers, and drive infrastruct...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$219K - $285K *

Shape the future of organizational strategy and capability within a thriving biotech firm. Collaborate with leaders and teams to enhance workforce effectiveness, streamline operations, and drive susta...

US-AnywhereRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$122K - $204K *

Elevate the energy data landscape by standardizing access to utility data. Collaborate with key stakeholders, analyze intricate datasets, and drive innovative solutions to enhance energy management sy...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $130K *

Engineer robust integrations across the GTM stack, optimizing Salesforce and HubSpot as engineering systems to ensure reliable data flow, build intelligent workflows, and empower teams to operate effi...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $130K *

Innovate as a Senior .NET Software Engineer, crafting impactful SaaS solutions. Collaborate within a dynamic remote team to design and enhance multi-tenant applications, driving efficiency and excelle...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Champion the design and execution of impactful technical enablement programs, enhancing practitioner competencies through onboarding and continuous learning initiatives while collaborating with cross...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $115K *

Advance public safety through strategic ecosystem partnerships and enterprise-level sales, managing complex solutions in Drone and Counter Drone technologies while collaborating across teams to enhanc...

US-AnywhereRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$77K - $120K *

Optimize project management for key infrastructure initiatives, ensuring timely execution and compliance. Collaborate with stakeholders to deliver high-quality engineering solutions and drive strategi...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$102K - $170K *

Elevate the platform experience by automating infrastructure and optimizing software delivery. Join a talented team focused on building a secure, reliable, scalable SaaS solution that enhances data re...

US-AnywhereRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $185K *

Unlock potential by administering and optimizing Oracle databases in cloud and on-prem environments, ensuring security, performance, and integration for critical applications supporting federal health...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$122K - $130K *

Join the Proactive Security team to enhance and lead vulnerability management initiatives. Strategically identify, prioritize, and remediate risks in a fast-paced environment while collaborating with...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$174K - $209K *

Join a dynamic team to enhance the performance and scalability of backend platforms. Collaborate with engineers across disciplines, take ownership of system reliability, and contribute to the developm...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$232K - $293K *

Lead a high-performing team focused on strategic technical engagement with partners. Drive co-innovation and ensure successful integrations while collaborating across functions to achieve technical ex...

US-AnywhereRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $130K *

Join a team that's shaping the future of cataract surgery through innovation and engineering excellence. Collaborate on cutting-edge surgical solutions in a fast-paced environment with strong cross-fu...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $130K *

Accelerate progress at the forefront of clinical research by designing and conducting studies that enhance our understanding of new therapies, while collaborating with multidisciplinary teams and appl...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K - $128K *

Drive impactful energy solutions by supporting the development and implementation of distributed energy projects. Collaborate with teams to execute innovative designs and ensure top-quality project de...

US-AnywhereRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$146K - $234K *

Optimize cloud infrastructure services by leading a diverse team to modernize and enhance a large-scale multi-tenant ecosystem for federal users, ensuring compliance and driving continuous improvement...

US-AnywhereRemote

4 weeks ago

  •   15+ years exp.  •   Information Technology

$89K - $148K *

Lead the charge in driving technical excellence and customer satisfaction, collaborating with sales teams and clients to develop innovative solutions in Industrial Communications that align with busin...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$186K - $242K *

Join a team that's driving the future of our core infrastructure by leading a diverse engineering group focused on mobile, web, and backend systems. Take ownership of critical projects while fostering...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $120K *

Lead the charge in delivering innovative project management solutions for health IT initiatives, overseeing complex projects and teams to drive efficiency in clinical software application development...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $173K *

Lead the charge in managing complex projects with multi-million dollar budgets. You'll ensure timely delivery and scope adherence while leveraging expertise in project governance, material handling, a...

US-AnywhereRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Business Services

$115K - $173K *

Grow your career with a key role overseeing complex warehouse automation projects, managing executive relationships, and driving performance across multi-disciplinary teams from beginning to successfu...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$136K - $210K *

Shape the future of AI security by safeguarding enterprise AI technologies, implementing effective governance, and driving secure AI adoption through risk assessments and collaboration with various te...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $150K *

Lead the charge in driving sales and developing key relationships in the Northwest region. Manage a skilled sales team, engage with distributors, and oversee strategic initiatives to achieve revenue g...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What does a Senior Principal Systems Engineer do?question toggle

    A Senior Principal Systems Engineer handles system architecture, leads technical teams, and solves advanced engineering problems. They're often responsible for guiding overall system design and integration.

  • What skills do I need to have for these roles?question toggle

    Skills commonly required include system design, team leadership, analytical thinking and knowledge in systems integration.

  • What industries hire Senior Principal Systems Engineers?question toggle

    Industries like Technology, Aerospace, Defense, Telecommunications, and more require the expertise of Senior Principal Systems Engineers.