Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$150K - $180K *

Transform your career by leading the legal function for a pioneering foundation. You'll navigate complex IP, AI regulation, and nonprofit governance, ensuring compliance while fostering innovation and...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$137K - $254K *

Join a dynamic team as a strategic advisor, engaging with senior leadership to drive AI transformation in legal and tax functions. Leverage your expertise to build relationships and influence technolo...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Media

$132K - $221K *

Drive enterprise-wide legal support for global contracting activities, focusing on procurement and technology transactions. Collaborate with cross-functional teams to manage risks and ensure complianc...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Champion the legal landscape by providing expert counsel on commercial, technology, privacy, and employment matters. Collaborate with diverse teams to draft, negotiate, and manage contracts while ensu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $190K *

Lead the legal strategy for a fast-growing stablecoin business, negotiating complex agreements and advising on commercial issues. Collaborate with cross-functional teams to scale products and enhance...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Join a dynamic legal team to manage general liability litigation cases, guiding clients through trial prep and court appearances while ensuring effective communication and superior advocacy skills...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$78K - $126K *

Unlock potential by providing expert compliance advisory services to diverse organizations. Collaborate with clients to enhance grant management, internal controls, and operational effectiveness throu...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$150K - $200K *

Lead client engagements by leveraging tax expertise to drive revenue growth, manage complex planning discussions, and enhance client relationships while ensuring strategic alignment across teams for o...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$175K - $210K *

Shape the future of corporate law by providing strategic legal counsel on M&A, governance, and compliance for a dynamic multinational company. Collaborate with diverse teams to navigate complex transa...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$213K - $335K *

Optimize legal operations by leveraging technology and AI to enhance efficiency, drive strategic projects, and foster collaboration within a fast-paced healthcare tech environment. Lead a team to impl...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $130K *

Unlock potential by managing complex D&O, EPL, and E&O claims. Analyze, negotiate, and resolve claims while ensuring compliance and fostering client relationships. Lead investigations and mentor team...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $135K *

Lead the charge in managing high-severity, complex insurance claims, focusing on EPL and Professional Liability. Serve as a subject matter expert, ensuring compliance and strategic resolution while ad...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$164K - $262K *

Partner with us to navigate the complexities of mortgage regulation while supporting innovative product development. This role offers a unique opportunity to influence the legal landscape of consumer...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$160K - $200K *

Lead the charge in shaping Stedi's litigation strategy, driving affirmative disputes and regulatory actions to protect and expand our operational freedom in the healthcare sector. Collaborate with lea...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$125K - $150K *

Join a team that's shaping the future of commercial legal operations by supporting diverse contracting efforts and building scalable legal frameworks that drive business growth and innovation...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $175K *

Transform your career by partnering with business teams in a dynamic legal environment. Leverage your commercial instincts and regulatory expertise to make an immediate impact across two brands in a f...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $130K *

Join a team that's driving corporate governance and entity management. This role offers significant responsibility, collaboration across departments, and opportunities for growth in a fast-paced envir...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$118K - $178K *

Shape strategic initiatives by leading key deliverables and financial analyses. Collaborate with partners to enhance business processes and drive impactful recommendations, ensuring alignment and time...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$184K - $253K *

Drive strategic partnerships and technology transactions as a Senior Counsel, overseeing complex agreements and M&A support. Collaborate cross-functionally to build processes and provide business-focu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $235K *

Elevate your legal career by delivering strategic counsel and effective services to Managed Services Organizations and physician practices, while managing complex legal projects and mentoring a team i...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Join us as a key legal advisor, shaping strategy and guiding executive leadership through complex regulatory and contractual matters while balancing legal risk with business objectives...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Transform the claims process by managing Property loss claims, guiding adjusters, and collaborating with underwriters. Leverage your expertise in policy coverage and communication to ensure effective...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$163K - $237K *

Lead the charge in shaping advertising agreements for a dynamic legal team. Collaborate across functions to drive growth in our ad tech initiatives while ensuring compliance and efficiency in a fast-p...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Champion innovation by providing legal guidance on digital identity products, ensuring compliance and risk management throughout the product lifecycle. Collaborate with cross-functional teams to navig...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$72K - $146K *

Elevate your career by driving impactful business development initiatives. Collaborate with cross-functional teams to enhance marketing strategies and client engagement, while supporting a growing Cor...

4 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.