Principal Systems Engineer Jobs in Durham, NC

Accelerate progress at the forefront of data center engineering by independently designing and managing complex infrastructure solutions, ensuring optimal performance and operational excellence across...

Shape the future of client partnerships by leading account strategies, enhancing client relationships, and driving financial performance across complex Life Sciences portfolios. Innovate solutions to...

Innovate cloud services for connected hardware as you enhance telemetry, state management, and integrations. Collaborate across teams and deepen your AI-native engineering skills to deliver reliable...

Architect the strategy for a cloud-based quantum developer platform, driving adoption by integrating classical computing workflows with quantum capabilities, defining future platform needs, and measur...

Pioneer impactful AI/ML solutions as you develop agentic LLM systems, managing their lifecycle from prototyping to production. Collaborate cross-functionally to design efficient RAG pipelines and enha...

Lead the design and management of high-performance network infrastructures, ensuring security, scalability, and compliance across diverse environments. Collaborate with teams to optimize network solut...

Unlock your potential as you build and maintain scalable cloud infrastructure, collaborating cross-functionally to enhance operational integrity and empower health solutions. Join us in revolutionizin...

Partner with us to drive the future of digital health solutions, focusing on patient engagement and the commercial launch of innovative medical products while providing cross-functional leadership and...

Innovate user experiences at the forefront of game development by leading UX/UI strategies for a new franchise. Collaborate across disciplines to enhance player engagement and ensure design excellence...

Champion cybersecurity efforts by leading complex incident responses and guiding junior analysts. Leverage advanced threat detection skills to enhance security operations and ensure effective containm...

Lead the charge in evolving our technology ecosystem by architecting high-velocity delivery models and integrating AI-driven solutions to enhance operational efficiency and decision-making across the...

Lead contract activities for innovative defense projects, collaborating across departments to ensure compliance and successful outcomes. Utilize your expertise to manage risk and drive project executi...

Join a team that's shaping the future of cybersecurity by developing full stack applications using cutting-edge technologies and best practices, while collaborating with diverse teams to deliver innov...

Lead the charge in post-award activities, transforming proposals into actionable plans while managing EPC agreements, risks, and operational handovers for successful project delivery...

Lead critical security investigations and respond to high-severity incidents. Mentor junior analysts and enhance threat detection capabilities while working collaboratively to support customers in a f...

Join a team that's driving secure architecture for multi-tenant SaaS applications. You'll advise product teams, lead threat modeling and design reviews, ensuring best practices in security while navig...

Join a dynamic Engineering Team to bridge market insights and technical expertise, ensuring product safety and design excellence while collaborating closely with sales and distribution partners across...

Lead engineering efforts to enhance product delivery, quality, and security. Manage a high-performing team while driving scalable processes, architectural decisions, and leveraging AI for sustainable...

Transform the future of our Camp Admin Experience by leading engineering teams through a complex architectural shift, reimagining core features to enhance customer experience and drive modernization i...

Take ownership of your development in a collaborative environment, where you'll build test suites, deploy open source software, and enhance complex systems documentation. Play a key role in ensuring s...

Pioneer advanced project management initiatives, overseeing large-scale consulting and construction services. Lead client relations, ensuring stellar delivery while managing complex projects and teams...

Create and support AI-driven content tooling solutions that enhance automation and management capabilities, collaborating in an Agile/Scrum environment to deliver high-quality software enhancements us...

Empower operations by managing Cold Chain logistics, ensuring quality compliance, optimizing data management, and addressing inquiries. You'll lead enhancements, training, and audits, fostering team c...

Join a team that leads product delivery and community engagement for an open source platform, bridging technical insights and customer needs. Drive strategic decisions while collaborating with cross-f...

Manage complex IT delivery across a portfolio, leading Project Managers and owning critical integrations. Drive discipline, execution, and program health in a dynamic, multi-platform environment while...