Principal Reliability Engineer Jobs

Discover Principal Reliability Engineer opportunities on Ladders, a destination for vetted professional jobs paying $100,000 or more. Principal Reliability Engineers guide the strategies and technical practices that help organizations build dependable products, systems, and operations. Explore senior-level roles where you can shape reliability programs, solve complex engineering challenges, and influence decisions across teams.

What Does a Principal Reliability Engineer Do?

Principal Reliability Engineers lead efforts to improve the availability, safety, durability, and performance of products or systems. Depending on the industry, they may analyze failure data, assess technical risks, develop reliability models, guide testing and validation, and recommend design or process changes. They often serve as senior technical authorities, partnering with engineering, operations, quality, and leadership teams.

Skills and Qualifications

Employers commonly seek extensive engineering experience and a track record of leading complex reliability initiatives. Relevant strengths may include failure-mode analysis, root-cause investigation, reliability statistics, systems engineering, risk assessment, test planning, and clear technical communication. Requirements vary by employer and industry; some positions may also call for specialized tools, standards, or experience with regulated environments.

Industries and Career Opportunities

Principal Reliability Engineer roles can be found across sectors such as aerospace, energy, manufacturing, medical technology, telecommunications, and software or cloud services. The work may focus on physical assets and products, mission-critical infrastructure, or distributed systems. Browse openings to find positions that match your technical background, preferred industry, and career goals.

Find Principal Reliability Engineer Jobs on Ladders

Use Ladders to explore vetted professional opportunities with salaries of $100,000 or more. Review job requirements, compare roles, and identify positions where your reliability expertise can have a broad impact.

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$100K - $120K *

Engage with cross-functional teams to drive clinical trial success across regions. Leverage your expertise in project management and mentoring to ensure compliance, quality, and timely execution of st...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $112K *

Transform engineering systems by optimizing CATIA and related tools, ensuring effective deployment and governance. Collaborate with cross-functional teams to enhance productivity and drive continuous...

Huntington Beach, CARemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Transform customer engagements by owning solution direction across multiple accounts. Drive platform adoption, orchestrate delivery teams, and shape opportunities to ensure measurable value and long-t...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$95K - $115K *

Lead global clinical laboratory projects by ensuring operational excellence, client satisfaction, and effective cross-functional collaboration while mentoring junior project managers to elevate team p...

Kentucky, USRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $145K *

Unlock your potential by designing CI/CD pipelines and automating processes. Collaborate with teams to enhance development efficiency while ensuring system compliance and security across AWS and Azure...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$111K - $180K *

Unlock potential by designing AI-powered solutions for complex reporting challenges. Collaborate with customers and cross-functional teams to deliver innovative outcomes in regulated environments whil...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$88K - $105K *

Advance your career by serving as the primary liaison between investigational sites and sponsors, ensuring compliance and supporting site operations across multiple therapeutic areas in a dynamic clin...

Florida, USRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$105K - $175K *

Lead the charge in Model-Based Systems Engineering, collaborating with experts across diverse domains to develop cutting-edge solutions. Utilize your skills in SysML and modeling tools to drive innova...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$145K - $190K *

Lead the design and evolution of scalable data architecture, providing technical leadership across teams to deliver reliable, secure, and cost-effective data solutions while shaping emerging capabilit...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $177K *

Transform enterprise infrastructure by embedding with client teams to optimize Kubernetes deployments, streamline migrations, and enhance AI capabilities, ensuring successful platform adoption and ope...

Tennessee, USRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$110K - $138K *

Lead the charge in clinical trial monitoring, ensuring compliance and quality. Collaborate with teams to enhance data integrity and site performance while providing training and support to maintain hi...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $102K *

Champion customer success by guiding Mid-Market clients through the deployment and adoption of IoT solutions, ensuring they maximize value from our technology while building strong relationships acros...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Join us to lead clinical trial monitoring, ensuring adherence to protocols and regulatory standards while fostering collaboration and quality improvement across multiple sites in the oncology field...

Burlington, ONRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$110K - $138K *

Join a team that's dedicated to delivering high-quality clinical trial outcomes while ensuring compliance and patient safety. Collaborate with stakeholders and investigators to drive efficient study m...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $138K *

Champion clinical trial excellence by overseeing monitoring activities, ensuring compliance with protocols and regulations, and fostering collaboration across teams to drive successful trial execution...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Lead clinical trial monitoring efforts, ensuring compliance with protocols and regulations while fostering collaboration across teams to enhance data integrity and site performance...

Blue Bell, PARemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform fire protection engineering for large-scale data centers by establishing design criteria, reviewing complex systems, and ensuring compliance from design through operational handover, while c...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Unlock the potential of software quality assurance by leading a skilled QA team to enhance testing strategies, processes, and automation, ensuring superior product quality across SaaS and On-Premises...

Oak Brook, ILRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $180K *

Unlock potential by leading application security initiatives, enhancing product security, and driving secure development practices. Collaborate with engineering teams to establish standards, manage vu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$83K - $116K *

Tackle complex technical challenges by delivering exceptional field support for bioprocessing products. Collaborate with cross-functional teams to enhance customer satisfaction and drive service excel...

New York, NYRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in building robust MLOps infrastructure to support scalable AI solutions, bridging software engineering and machine learning for reliable production deployments across enterprise envir...

Cambridge, MARemote

Reposted today

  •   8 - 10 years exp.  •   Staffing

$80K - $121K *

Unlock the potential of customer learning by delivering innovative, impactful training experiences. Drive engagement through digital programs and live sessions, ensuring thousands of customers succeed...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $200K *

Contribute to the design and analysis of vital water infrastructure projects, ensuring compliance and quality. Lead multidisciplinary teams, mentor junior engineers, and engage with clients to deliver...

Rancho Cordova, CARemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$160K - $200K *

Lead the design and analysis of water infrastructure projects, ensuring compliance and innovation. Collaborate with multidisciplinary teams to deliver sustainable solutions that enhance community serv...

Oakland, CARemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$160K - $200K *

Engage in the design and analysis of vital water infrastructure projects. Lead multidisciplinary teams to deliver innovative solutions, ensuring compliance and quality while mentoring junior engineers...

Riverside, CARemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What does a Principal Reliability Engineer do?question toggle

    A Principal Reliability Engineer leads technical work to improve the dependability, safety, availability, and performance of products or systems. Responsibilities may include risk analysis, failure investigation, reliability modeling, testing strategy, and cross-functional technical guidance.

  • What qualifications are typically needed for Principal Reliability Engineer jobs?question toggle

    Employers often look for substantial engineering experience, expertise in reliability methods, and the ability to lead complex technical initiatives. Specific requirements vary by role and may include industry-specific standards, tools, or credentials.

  • Which industries hire Principal Reliability Engineers?question toggle

    Common employers operate in aerospace, energy, manufacturing, medical technology, telecommunications, and software or cloud services, among other sectors.

  • How can I find Principal Reliability Engineer jobs paying $100,000 or more?question toggle

    Browse Principal Reliability Engineer listings on Ladders, where you can explore vetted professional jobs with salaries of $100,000 or more and review opportunities suited to your experience.