Principal Reliability Engineer Jobs

Discover Principal Reliability Engineer opportunities on Ladders, a destination for vetted professional jobs paying $100,000 or more. Principal Reliability Engineers guide the strategies and technical practices that help organizations build dependable products, systems, and operations. Explore senior-level roles where you can shape reliability programs, solve complex engineering challenges, and influence decisions across teams.

What Does a Principal Reliability Engineer Do?

Principal Reliability Engineers lead efforts to improve the availability, safety, durability, and performance of products or systems. Depending on the industry, they may analyze failure data, assess technical risks, develop reliability models, guide testing and validation, and recommend design or process changes. They often serve as senior technical authorities, partnering with engineering, operations, quality, and leadership teams.

Skills and Qualifications

Employers commonly seek extensive engineering experience and a track record of leading complex reliability initiatives. Relevant strengths may include failure-mode analysis, root-cause investigation, reliability statistics, systems engineering, risk assessment, test planning, and clear technical communication. Requirements vary by employer and industry; some positions may also call for specialized tools, standards, or experience with regulated environments.

Industries and Career Opportunities

Principal Reliability Engineer roles can be found across sectors such as aerospace, energy, manufacturing, medical technology, telecommunications, and software or cloud services. The work may focus on physical assets and products, mission-critical infrastructure, or distributed systems. Browse openings to find positions that match your technical background, preferred industry, and career goals.

Find Principal Reliability Engineer Jobs on Ladders

Use Ladders to explore vetted professional opportunities with salaries of $100,000 or more. Review job requirements, compare roles, and identify positions where your reliability expertise can have a broad impact.

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$80K - $95K *

Join a dynamic team as a Product Engineer, driving innovative designs and technical solutions for mass production. Collaborate across departments to ensure product excellence and mentor junior enginee...

Wayne, NERemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $300K *

Lead the charge in optimizing the customer journey from landing page to long-term conversion. Drive growth through experimentation, retention strategies, and revenue expansion while collaborating with...

San Francisco, CARemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$159K - $273K *

Lead the future of software engineering by driving architectural modernization, strategic vision, and impactful solutions. Partner with executives and multidisciplinary teams to solve healthcare chall...

Eden Prairie, MNRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Lead the technical health of a claims platform by enhancing applications, ensuring system stability, and bridging engineering with business needs. This hybrid role combines hands-on development with s...

Cincinnati, OHRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $150K *

Unlock potential by leading cross-functional teams to deliver high-quality capital projects in regulated environments. Drive operational excellence and mentor talent while ensuring compliance with saf...

Indiana, USRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $120K *

Lead the charge in regulatory affairs by providing strategic guidance, ensuring compliance, and fostering collaboration across institutions. Drive initiatives from research to implementation while men...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$179K - $254K *

Join a team that's driving the future of mobility and IoT! Oversee product lifecycles, collaborate with executives, and navigate complex networks to align cutting-edge solutions with customer needs an...

RemoteRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$140K - $190K *

Drive innovation in healthcare analytics as a Senior Lead Software Engineer, leading product development, designing ETL processes, and mentoring a collaborative team to enhance patient outcomes throug...

Chicago, ILRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$106K - $159K *

Transform regulatory strategies by providing CMC expertise to support product development and compliance in a dynamic pharmaceutical environment, ensuring quality and adherence to global standards thr...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$130K - $196K *

Champion integrated workforce strategies that enhance talent planning, drive employee growth, and strengthen leadership pipelines. Collaborate across functions to translate insights into scalable proc...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Help us build and scale cutting-edge ML infrastructure for innovative protein design. Collaborate with scientists and engineers to enhance research velocity through robust data pipelines and productio...

San Diego, CARemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$139K - $174K *

Lead structural design for complex projects, focusing on data centers and industrial facilities. Collaborate with multidisciplinary teams, ensuring quality and compliance while mentoring junior engine...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$160K - $190K *

Make your mark at a leading platform by architecting and maintaining high-throughput AWS infrastructure, ensuring optimal performance and security for millions of users while driving automation and re...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $250K *

Pioneer innovative solutions in enterprise healthcare by owning product development, enhancing EMR integrations, and streamlining implementations to ensure rapid adoption and customer satisfaction acr...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$116K - $145K *

Innovate and enhance user experiences by designing and developing robust software solutions. Collaborate with cross-functional teams to deliver impactful projects while mentoring junior engineers and...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$140K - $190K *

Drive the unification of diverse analytics applications by providing technical leadership and hands-on engineering expertise. Collaborate with teams to design scalable solutions, mentor engineers, and...

Chicago, ILRemote

5 days ago

  •   5 - 7 years exp.  •   Business Services

$130K - $155K *

Lead cross-functional teams to drive enterprise modernization through AI solutions. Oversee complex implementations, ensuring alignment across technical and business stakeholders while delivering meas...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Drive operational excellence by supporting managed services infrastructure, ensuring seamless incident response, systems administration, and network troubleshooting while collaborating with internal t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $165K *

Drive the development of a centralized data warehouse for biomedical research, enhancing data integration and functionality. Collaborate with teams to optimize data pipelines and support national rese...

Connecticut, USRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$97K - $192K *

Deliver expert engineering solutions for high voltage substation projects, ensuring compliance with industry standards. Collaborate with teams to design and execute projects up to 500 kV, while mentor...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$118K - $196K *

Oversee compliance and audit processes for HR Systems, ensuring operational risk management and adherence to regulatory standards while collaborating with cross-functional teams to safeguard employee...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Join a team that shapes global regulatory strategy in a fast-paced environment. You will lead comprehensive regulatory plans, ensuring alignment and execution from development to post-marketing, impac...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive the technical design and delivery of innovative AI agent solutions, leading a team to ensure operational readiness and quality. Collaborate with stakeholders to define requirements and guide eng...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Transform legal research by enabling AI adoption in law firms. Collaborate with leaders to design effective workflows, enhance vendor partnerships, and build internal AI capabilities, ensuring clients...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Lead the charge in shaping network infrastructure standards for data centers. Collaborate with cross-functional teams to ensure compliance and excellence in design, construction, and acceptance of tel...

Texas, USRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What does a Principal Reliability Engineer do?question toggle

    A Principal Reliability Engineer leads technical work to improve the dependability, safety, availability, and performance of products or systems. Responsibilities may include risk analysis, failure investigation, reliability modeling, testing strategy, and cross-functional technical guidance.

  • What qualifications are typically needed for Principal Reliability Engineer jobs?question toggle

    Employers often look for substantial engineering experience, expertise in reliability methods, and the ability to lead complex technical initiatives. Specific requirements vary by role and may include industry-specific standards, tools, or credentials.

  • Which industries hire Principal Reliability Engineers?question toggle

    Common employers operate in aerospace, energy, manufacturing, medical technology, telecommunications, and software or cloud services, among other sectors.

  • How can I find Principal Reliability Engineer jobs paying $100,000 or more?question toggle

    Browse Principal Reliability Engineer listings on Ladders, where you can explore vetted professional jobs with salaries of $100,000 or more and review opportunities suited to your experience.