Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$79K - $118K *

Champion exceptional patient care as a skilled RN in a dynamic emergency department. Leverage your expertise to provide comprehensive nursing services, ensuring safety and quality in a fast-paced envi...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $118K *

Unlock potential by delivering exceptional emergency care in a dynamic environment. Collaborate with interdisciplinary teams to enhance patient outcomes while thriving in a fast-paced, high-acuity set...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $118K *

Join a dynamic Emergency Department team delivering critical care to diverse patients. Utilize your nursing skills in a fast-paced environment, ensuring optimal outcomes through collaboration and evid...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $156K *

Transform the product marketing landscape by executing strategic go-to-market plans, ensuring cohesive messaging across athenaOne offerings. Collaborate with cross-functional teams to drive market und...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Play a key role in transforming raw data into actionable insights by building machine-learning systems. Collaborate across teams to analyze complex datasets and create innovative models for logistics...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Transportation

$77K - $106K *

Elevate your nursing career by providing personalized, in-home care to patients. Collaborate with a dedicated healthcare team to develop care plans, monitor progress, and educate families, all while m...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $210K *

Shape the future of oncology partnerships by driving strategy and execution to expand Daymark's network among leading practices focusing on value-based care. Cultivate relationships, close deals, and...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Transform the future of cloud infrastructure by automating and optimizing systems for reliability, performance, and scalability, collaborating with engineering teams to embed best practices and foster...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Advance patient care by providing flexible, high-quality services in urgent care, primary care, and telemedicine. Collaborate with diverse teams in a fast-paced environment to ensure effective treatme...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Join a dynamic team providing patient-focused care across multiple clinics. Deliver urgent and primary medical services, including telemedicine, in a fast-paced environment while leading and collabora...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Pioneer patient-focused care in a dynamic urgent care setting, leading a team while utilizing your full scope of practice. Engage with diverse patient populations and enhance your skills in a supporti...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Empower your career by joining a dynamic team providing comprehensive urgent care. Lead a small team while delivering patient-focused care across all ages in a fast-paced environment. Enjoy unmatched...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Join us to provide comprehensive patient care in a dynamic urgent care setting. Lead a dedicated team while utilizing your full scope of practice to treat diverse patient needs, ensuring quality healt...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Join a team that's dedicated to providing comprehensive urgent care services, treating patients of all ages in a fast-paced environment. Utilize your full scope of practice while leading a supportive...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Join a team that's dedicated to providing comprehensive patient care in a fast-paced urgent care environment. Empower yourself and others while utilizing your full scope of practice to make a meaningf...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Empower your nursing career by providing comprehensive care in a dynamic urgent care setting. Lead a dedicated team while treating patients of all ages, enhancing your skills and making a meaningful i...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Champion patient-focused care in a dynamic environment, providing urgent and primary medical services. Collaborate with diverse teams across clinics, ensuring high-quality treatment and leadership in...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Champion patient care by leading a dynamic team in a fast-paced urgent care setting. Utilize your full scope of practice to treat diverse patients, while receiving unmatched support and training to en...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $170K *

Drive strategic excellence in sponsor operations, ensuring high-quality project delivery and alignment across enterprise programs. Manage a team of leaders to foster innovation and optimize operationa...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$245K - $286K *

Elevate clinical quality assurance through strategic leadership and oversight of global trials, ensuring compliance with GCP regulations. Drive quality culture and inspection readiness while mentoring...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform your career by driving customer success and technical solutions. Collaborate with cross-functional teams to enhance client relationships, identify growth opportunities, and ensure maximum va...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$265K - $300K *

Shape the future of neurodegenerative disease diagnostics by leading scientific strategy, driving research programs, and building expert networks to establish industry leadership in innovative solutio...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Champion the development of clinical operations by managing a network of providers, establishing policies, and enhancing quality programs. Collaborate with leadership to ensure operational excellence...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Manage the end-to-end onboarding of healthcare clients, leading cross-functional teams to ensure smooth transitions into coding and billing services while driving operational improvements and maintain...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $190K *

Join a team that's dedicated to advancing precision medicine by leveraging AI to provide cutting-edge educational support and scientific expertise on cancer biomarker tests while engaging key opinion...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.