Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$63K - $97K *

Support clinical trial operations by monitoring lab services, engaging with sites, and ensuring compliance with regulations. Collaborate with teams to enhance processes and deliver timely results for...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$186K - $233K *

Pioneer innovative strategies in breast oncology, driving commercial success through collaboration and data-driven insights. Lead cross-functional teams to enhance product adoption and optimize market...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive profitability and organic growth in retirement solutions by cultivating client relationships, leading new business development, and leveraging strategic partnerships to deliver tailored investme...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$113K - $188K *

Transform business needs into actionable insights by serving as a Business Analyst for ServiceNow initiatives. Collaborate with stakeholders to enhance platform solutions, streamline processes, and en...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Business Services

$175K - $205K *

Transform client relationships and drive growth by leading strategic initiatives in scientific visualization, medical education, and digital engagement. Manage multidisciplinary teams and oversee acco...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$205K - $228K *

Champion patient-focused initiatives by leading strategy and execution of ambassador programs. Build relationships with patients and advocacy groups to enhance engagement and ensure their voices shape...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$136K - $195K *

Drive revenue growth and market adoption of chromatography columns. Engage with biopharmaceutical manufacturers to support process development and commercialization, while building strong relationship...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$169K - $220K *

Join a team that's dedicated to transforming healthcare through innovative software solutions. Collaborate with engineers and healthcare professionals to build systems that enhance patient care and st...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Elevate client success by leading high-stakes projects and cultivating strong relationships while driving innovative solutions and business growth in a dynamic consulting environment...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Drive strategic growth and business development for National Accounts in Urology and Oncology, optimizing resources and leading negotiations to enhance healthcare outcomes through innovative diagnosti...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $175K *

Lead the charge in transforming financial operations while ensuring compliance and accuracy. Collaborate with cross-functional teams to enhance processes, manage audits, and drive strategic initiative...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$98K - $134K *

Elevate customer training and support as you guide medical professionals in using advanced technology and procedures efficiently while ensuring safe and effective operations, focusing on clinical exce...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$71K - $140K *

Unlock potential by joining our Operations Transformation team to support rural health initiatives. You'll conduct research, prepare materials, and coordinate project deliverables, all while collabora...

2 days ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Empower customer success by serving as the primary technical contact, enhancing solution stability and satisfaction through expert guidance and relationship building in a dynamic, fast-paced environme...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$76K - $114K *

Shape the future of healthcare by driving growth in Electrophysiology-focused Ambulatory Surgery Centers. Leverage your clinical expertise to build relationships, enhance product adoption, and ensure...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Shape the future of natural resource management by leading diverse projects, conducting wetland assessments, and collaborating with an interdisciplinary team. Elevate your career while managing client...

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$74K - $112K *

Unlock your potential by providing tailored occupational therapy to children, collaborating with multidisciplinary teams, and mentoring future therapists while fostering a supportive environment for g...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Transform the surgical center's operations by leading nursing staff, ensuring quality care, and managing resources effectively. Drive improvements in patient safety and operational efficiency while fo...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$349K - $396K *

Lead the charge in driving national growth strategies for enterprise employers, managing a top-performing sales team focused on Fortune 500 engagements, overseeing the acquisition lifecycle, and ensur...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$103K - $173K *

Manage and elevate vendor relationships in a highly regulated environment, ensuring governance, performance optimization, and risk oversight across technology, operations, and business functions to de...

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Empower the growth of in-person behavioral healthcare by leading strategic operations, enhancing provider acquisition, and ensuring compliance. Drive high-impact initiatives while collaborating across...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $155K *

Elevate your career by leading predictive modeling initiatives that drive business solutions and enhance member experiences. Collaborate with teams to innovate and implement advanced data science tech...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$109K - $179K *

Drive your career forward by translating complex scientific data into clear regulatory narratives, collaborating with cross-functional teams to support drug development and ensure consistent messaging...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $135K *

Unlock potential by leading client service strategies that enhance relationships, drive satisfaction, and foster retention. Collaborate across teams to deliver tailored solutions for complex client ne...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$79K - $102K *

Champion customer success by guiding Mid-Market clients through the deployment and adoption of IoT solutions, ensuring they maximize value from our technology while building strong relationships acros...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.