Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$85K - $100K *

Transform healthcare analytics by supporting ACOs in the MSSP program. Leverage data-driven insights to track performance metrics, optimize risk scores, and collaborate with teams to enhance value-bas...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $250K *

Shape the future of environmental engineering by leading complex remediation projects. Drive strategic oversight, ensure regulatory compliance, and cultivate a high-performing team. Use your expertise...

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$175K - $250K *

Serve as the senior technical expert for a national environmental remediation portfolio. Lead strategy and oversight on complex projects while mentoring a team of engineers, ensuring compliance with f...

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$127K - $140K *

Pioneer the operational backbone of a rapidly growing team, optimizing Salesforce and managing commercial systems. Build infrastructure, enhance rep efficiency, and streamline event logistics, while d...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $105K *

Champion a team committed to excellence in ABA services by leading daily clinic operations, fostering a supportive culture, and driving community engagement to improve lives and achieve impactful outc...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $170K *

Drive business growth by building relationships and delivering innovative solutions in the Higher Education sector. Leverage your expertise in sales and strategic transformation to meet client needs a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$66K - $111K *

Lead a dynamic team of Financial Service Professionals to enhance client relationships by delivering exceptional, proactive service. Drive engagement, coach for excellence, and leverage insights to el...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$96K - $133K *

Join a team that's dedicated to delivering high-quality projects on time and within budget. As a key player, you'll coordinate efforts across departments, ensuring effective communication and resource...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower patient care by leading a multidisciplinary team, enhancing nursing practices, and driving quality initiatives. Collaborate across specialties to deliver exceptional healthcare services while...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Elevate customer experiences by leading a team of engineers, providing strategic insights, and implementing innovative solutions in growth engineering and digital marketing for impactful delivery serv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $200K *

Lead client engagements by leveraging tax expertise to drive revenue growth, manage complex planning discussions, and enhance client relationships while ensuring strategic alignment across teams for o...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$79K - $116K *

Unlock potential by leading performance improvement initiatives, coordinating projects, and collaborating with medical staff to enhance trauma care outcomes while ensuring compliance and contributing...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Engage in comprehensive patient care as a vital member of our healthcare team. You will conduct evaluations, manage treatments, and educate patients, ensuring high-quality medical services and support...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $150K *

Lead the charge in integrating complex hospital data systems into Astra OS. Own end-to-end data pipelines, collaborate with customers, and design scalable solutions that enhance healthcare operations...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$285K - $310K *

Lead the strategic execution of global clinical trials, ensuring adherence to timelines, budgets, and quality standards while fostering collaboration across teams and mentoring Clinical Operations per...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$63K - $97K *

Support clinical trial operations by monitoring lab services, engaging with sites, and ensuring compliance with regulations. Collaborate with teams to enhance processes and deliver timely results for...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$186K - $233K *

Pioneer innovative strategies in breast oncology, driving commercial success through collaboration and data-driven insights. Lead cross-functional teams to enhance product adoption and optimize market...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive profitability and organic growth in retirement solutions by cultivating client relationships, leading new business development, and leveraging strategic partnerships to deliver tailored investme...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$113K - $188K *

Transform business needs into actionable insights by serving as a Business Analyst for ServiceNow initiatives. Collaborate with stakeholders to enhance platform solutions, streamline processes, and en...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Business Services

$175K - $205K *

Transform client relationships and drive growth by leading strategic initiatives in scientific visualization, medical education, and digital engagement. Manage multidisciplinary teams and oversee acco...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$205K - $228K *

Champion patient-focused initiatives by leading strategy and execution of ambassador programs. Build relationships with patients and advocacy groups to enhance engagement and ensure their voices shape...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$136K - $195K *

Drive revenue growth and market adoption of chromatography columns. Engage with biopharmaceutical manufacturers to support process development and commercialization, while building strong relationship...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$169K - $220K *

Join a team that's dedicated to transforming healthcare through innovative software solutions. Collaborate with engineers and healthcare professionals to build systems that enhance patient care and st...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Elevate client success by leading high-stakes projects and cultivating strong relationships while driving innovative solutions and business growth in a dynamic consulting environment...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Drive strategic growth and business development for National Accounts in Urology and Oncology, optimizing resources and leading negotiations to enhance healthcare outcomes through innovative diagnosti...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.