Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Executive Director, Patient Solutions Operations
$160K - $190K *
Drive operational excellence in patient support programs, enhancing access and outcomes through strategic leadership, compliance, and team development. Oversee key functions to ensure a patient-center...
4 days ago
Senior Consultant - Data Platforms & Architecture
$103K - $154K *
Unlock advanced data solutions by leveraging Microsoft Azure and Power BI. Collaborate with teams to deliver high-quality analytics and reporting, while enhancing business intelligence capabilities th...
4 days ago
Manager, Revenue Cycle Operations
$100K - $130K *
Join a dynamic team to lead and enhance billing and coding operations, ensuring quality and compliance across multiple markets. Drive performance, coach leaders, and collaborate cross-functionally to...
2 weeks ago
Psychiatric Nurse Practitioner - CA Virtual (FT)
$140K *
Join a team that's dedicated to delivering innovative mental health care through comprehensive evaluations and tailored treatment plans, utilizing advanced techniques in a collaborative, fast-paced en...
3 weeks ago
Hybrid Board Certified Behavior Analyst (BCBA) - Remote / In-Person
$90K - $100K *
Lead the delivery of high-quality ABA therapy in a hybrid role, balancing remote and in-person client engagement. Collaborate with clinical teams to develop individualized behavior plans and support f...
5 days ago
Occupational Therapist, Outpatient, Pediatric
$79K - $118K *
Join a team that shapes the future of pediatric rehabilitation through innovative care delivery. Collaborate with healthcare professionals to provide comprehensive treatment plans, enhance patient out...
3 weeks ago
Sr. Solution Architect, Professional Services - Agentic AI
$121K - $132K *
Engage as a key technical leader in enterprise AI/ML architecture, collaborating with clients to design scalable solutions. Drive AI development and deployment, ensuring alignment with business needs...
3 weeks ago
$110K - $130K *
Lead end-to-end client implementations, ensuring timely and impactful project delivery while collaborating across teams to drive exceptional customer experiences and measurable outcomes in a dynamic h...
1 month ago
$120K - $150K *
Unlock operational excellence by leading multi-site Ambulatory Surgery Centers. Drive growth strategies, optimize performance, and foster strong partnerships with physician leaders while managing sign...
Reposted 2 days ago
Director, Public Safety Operations
$130K - $150K *
Champion public safety operations across North America, leading program directors to ensure effective training, deployment, and customer satisfaction while aligning resources and operational prioritie...
3 days ago
Registered Nurse (RN) - Operating Room FT Days
$79K - $118K *
Engage in delivering high-quality surgical care as a Registered Nurse in a dynamic Operating Room team, collaborating with surgeons and anesthesiologists to ensure safe, compassionate, and patient-cen...
3 days ago
Nurse Manager, AC - Spine Services Clinic
$85K - $100K *
Champion exceptional patient care and operational excellence as you lead nursing services in our ambulatory clinics. Drive quality improvement and optimize workflows, ensuring compliance with regulato...
Reposted 1 week ago
Senior Engineer, Back-End (Security Controls)
$199K - $270K *
Tackle the complexities of backend engineering by developing robust API integrations, building ETL pipelines, and collaborating with cross-functional teams to enhance system reliability and performanc...
Reposted 4 weeks ago
Solutions Integration Engineer IV
$105K - $160K *
Take ownership of B2B integrations as a key technical leader, collaborating across teams to deliver effective solutions that drive customer success and evolve with innovative IoT technology. Expect a...
Reposted 3 weeks ago
Senior Director, Head of Enterprise Clinical AI & Technology - Remote - The Cigna Group
$193K - $322K *
Join a team that leads the charge in advancing clinical AI and technology, shaping solutions that enhance clinician experience and patient outcomes while navigating complex healthcare environments...
1 month ago
Senior Architect, Professional Services
$170K - $220K *
Shape the future of customer solutions by leading implementations and driving adoption of innovative technologies. Collaborate with teams to deliver tailored architectural designs that meet strategic...
5 days ago
Telehealth Preventative Primary Care Advanced Practice Provider- NP/PA
$115K - $140K *
Unlock potential by joining a mission-driven team focused on preventative care. Collaborate with healthcare professionals to enhance patient health and quality of life through comprehensive assessment...
1 week ago
Associate Medical Director (Promotional Medical Education)
$100K - $125K *
Manage a team of medical writers to develop impactful scientific content, ensuring accuracy and compliance. Collaborate with clients and cross-functional teams to drive medical strategies and delivera...
Reposted 1 week ago
Senior ML Systems Engineer, Inference
$150K - $220K *
Transform LLM inference efficiency by leading the performance measurement, diagnosis, and enhancement efforts to optimize customer experience through cost-effective and speedy solutions in a hands-on...
4 weeks ago
Director, Strategic Advisory Services - Theranostics, Radiopharmaceuticals, and Oncology
$156K - $235K *
Accelerate your career by leading Theranostics initiatives within a national healthcare advisory team. Collaborate with executives to enhance patient outcomes and operational performance through strat...
Yesterday
Director, Neurology - Thought Leader Liaison (SOUTHEAST)
$245K - $265K *
Shape the future of neurology by building partnerships with Medical Experts, driving insights, and collaborating across teams to enhance patient care and strategic initiatives in a dynamic healthcare...
1 week ago
$110K - $130K *
Join a team that's at the forefront of cybersecurity, leading advanced incident response efforts. As a senior operational lead, you'll coordinate critical responses, ensuring effective communication a...
1 week ago
Medical Director, Medical Affairs
$174K - $374K *
Lead the charge in clinical oversight and mentorship, driving innovative medical solutions across diverse programs. Collaborate with cross-functional teams to ensure evidence-based decision-making and...
1 week ago
Senior Software Engineer- Backend GoLang (Remote)
$89K - $170K *
Pioneer innovative software solutions by developing and maintaining high-quality applications. Collaborate within a cross-functional team to enhance system performance and reliability, ensuring except...
1 week ago
Medical Monitor (US Board-Certified Gastroenterologist)
$210K - $250K *
Innovate with us to enhance patient safety in global clinical studies. As a key medical expert, you'll provide critical input, oversee trial safety, and collaborate with teams to ensure compliance and...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.