Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$155K - $210K *

Drive success by championing patient needs and executing strategic account plans. Leverage clinical expertise and business acumen to exceed sales goals while fostering relationships with key stakehold...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dynamic team where you'll take ownership of key Corporate Performance Management projects, executing tasks from build to testing, while collaborating with clients and delivering high-quality wo...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $120K *

Shape the future of medical technology by launching innovative solutions and training healthcare teams. Drive customer satisfaction and sustainable practices while collaborating with surgical teams to...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$114K - $171K *

Shape the future of pharmaceutical care by overseeing safe medication practices, engaging with patients, and collaborating with healthcare teams to optimize therapy regimens and enhance patient outcom...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Shape the future of customer relationships by driving value and retention for large organizations, collaborating closely with sales and product teams to ensure success and growth through data-driven i...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a dynamic anesthesia care team delivering compassionate and efficient anesthesia services across diverse surgical cases, focusing on patient safety and effective pain management. Enjoy a flexible...

1 month ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$102K - $177K *

Lead the charge in developing innovative spine marketing strategies that drive growth and enhance patient care. Collaborate with cross-functional teams to create compelling campaigns that resonate wit...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive strategic leadership for clinical dosimetry across multiple sites, ensuring high-quality treatment planning and operational excellence. Collaborate with interdisciplinary teams to innovate workf...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$92K - $153K *

Drive impactful data solutions by leveraging analytics and visualization tools. Collaborate with clients to enhance decision-making processes and optimize workflows, ensuring data-driven insights alig...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$230K - $310K *

Shape the future of IT Infrastructure & Operations by leading strategy and delivery for rapid growth and innovation in a tech-driven environment, ensuring security, scalability, and support across mul...

RemoteRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Transportation

$150K - $180K *

Innovate data-driven strategies to enhance business decision-making and optimize reporting processes. Leverage expertise in BI, CRM Analytics, and Salesforce to deliver actionable insights and support...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $216K *

Engage with clients as a NERC CIP Subject Matter Expert, leading project workstreams and driving compliance solutions. Foster industry relationships and support business development to enhance client...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$186K - $234K *

Grow your career by driving sales and building relationships in the neurology and rare disease sectors. Collaborate with healthcare professionals to enhance patient care and achieve sales targets whil...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$72K - $87K *

Support student development by administering therapeutic protocols and screenings. Collaborate with professionals to address emotional needs and manage behaviors effectively in a school-based environm...

2 days ago

  •   Less than 5 years exp.  •   Staffing

$175K - $210K *

Lead global field operations, driving strategy and execution across sales, technical services, and partner functions. Collaborate with senior leadership to optimize pipeline management, forecasting, a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$89K *

Empower your nursing career by providing exceptional care and support. Lead a team while ensuring the health and safety of residents. Join us in enhancing lives through compassionate and dedicated nur...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Join a team that partners with leaders to enhance organizational performance, drive employee engagement, and implement talent development initiatives in a fast-paced, global environment while supporti...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive operational excellence in referral management by leading a dynamic team, optimizing processes, and enhancing patient access across multiple service lines. Collaborate cross-functionally to ensur...

North Carolina, USRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Empower innovation in clinical trials by developing strategies, overseeing operations, and cultivating partnerships. Drive excellence in research, enhance compliance, and manage a high-performing team...

RemoteRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$52K - $108K *

Champion third-party risk management by delivering quality assessments, coordinating projects, and enhancing client engagement. Collaborate with teams to ensure timely execution and transparency acros...

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Lead critical care initiatives in a collaborative team environment, providing exceptional patient care in an inpatient setting. Engage in diverse procedures and support both day and night shifts, ensu...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$145K - $175K *

Lead the charge in managing enterprise client relationships, translating AI workforce development into measurable business impact. Drive strategic account plans, build trusted partnerships, and ensure...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $185K *

Unlock business growth by leading technical scoping, managing client relations, and guiding consultants. This hybrid role integrates project management with hands-on consulting to ensure accurate prop...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$88K - $105K *

Join a team that's shaping the future of industrial control systems. Leverage your expertise in design and implementation while collaborating with multidisciplinary teams across diverse sectors to del...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$105K - $115K *

Optimize security measures by leading technical solutions to mitigate information risks. Ensure compliance with corporate policies and oversee incident response, safeguarding all computing platforms a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.