Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$217K - $281K *

Champion cybersecurity excellence by leading CrowdStrike Falcon deployments, optimizing client engagements, and mentoring teams to enhance security operations and client relationships in a dynamic env...

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$250K - $275K *

Join us to lead clinical operations for a multi-state virtual care team, ensuring high-quality, timely care. This role combines direct patient care, administrative leadership, and strategic oversight...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$100K - $165K *

Drive impactful product deployments by leading comprehensive customer interactions, defining configurations, and ensuring successful integration of conversational AI systems into clinical workflows fo...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a dynamic team to lead the creation of impactful scientific content, enhancing medical education and patient outcomes. Collaborate cross-functionally, mentor writers, and drive excellence in heal...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$73K - $110K *

Join a dynamic team in the Cardiac Cath Lab, delivering critical patient care through advanced procedures and technology. Collaborate with healthcare professionals to ensure optimal outcomes in a fast...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$99K *

Unlock potential by providing technical support for HR technology solutions, focusing on Workforce Management and Staff Scheduling. Collaborate with IT and operational teams to enhance system performa...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$99K *

Join a team that's dedicated to enhancing HR technology solutions. This role focuses on supporting, configuring, and implementing Workforce Management and Staff Scheduling applications, ensuring optim...

Morrisville, NCRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Join a dynamic team dedicated to providing compassionate, individualized ABA care. Play a key role in supporting children with autism through effective treatment strategies, collaboration, and mentors...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Unlock potential by leading a dedicated team of BCBAs in providing compassionate, individualized ABA care. Enjoy a supportive environment with flexible scheduling, professional growth opportunities, a...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Grow your career with a supportive team dedicated to providing high-quality ABA services. Collaborate with caregivers and supervise clinical teams to enhance client outcomes in a nurturing environment...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$121K - $262K *

Transform client risk management by delivering expert insurance strategies, collaborating with Wealth Advisors to assess needs, design solutions, and implement comprehensive plans for high-net-worth c...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $110K *

Drive excellence in nursing care by overseeing operations, staff management, and compliance in a dynamic health center environment. Lead a dedicated team to ensure high-quality patient outcomes and re...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Optimize mission readiness by delivering comprehensive psychological services, enhancing resilience, and addressing behavioral health issues for service members and their families, ensuring peak perfo...

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$120K - $150K *

Lead the charge in elevating client success through strategic relationship management, team development, and robust operational frameworks to ensure exceptional service delivery and client satisfactio...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Transform healthcare outcomes by leveraging clinical expertise to review medical records, ensuring compliance with government standards while fostering collaboration and maintaining confidentiality in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$208K - $235K *

Join a dynamic team to architect scalable cloud solutions, ensuring high engineering standards while collaborating with cross-functional stakeholders to drive innovation and governance in a fast-paced...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$99K - $148K *

Join a dynamic surgical team in a hybrid role, balancing outpatient and inpatient care. Collaborate with experienced physicians, assist in surgeries, and enhance your skills in a supportive environmen...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$146K - $182K *

Transform regulatory strategies in FDA Pharma and IVDR, ensuring compliance and driving product approvals. Collaborate with cross-functional teams, mentor associates, and enhance processes to support...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$166K - $250K *

Lead the charge in driving technical sales of innovative health solutions across payer and employer segments. Foster deep relationships and collaborate with teams to establish partnerships that genera...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$79K - $118K *

Empower your nursing career by delivering exceptional patient care, collaborating with teams, and driving quality initiatives. Utilize your clinical expertise to enhance patient outcomes in a dynamic...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $350K *

Join a dynamic team to deliver expert wound management in a flexible, mobile practice. Enjoy work-life balance with no nights or weekends while earning competitive compensation and gaining specialized...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$230K - $250K *

Lead the charge in shaping a premium brand vision while driving creative strategy and operational excellence in a high-growth environment. Collaborate with cross-functional teams to elevate brand iden...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $118K *

Join a dynamic nursing team in a fast-paced observation unit, providing compassionate care to acute patients. Utilize your skills in a supportive environment focused on patient safety and experience...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Advance your career by developing a new influencer partnership channel that boosts patient engagement and drives revenue. You'll source and negotiate deals while optimizing partnerships, all in a fast...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $135K *

Innovate and lead client engagements, driving strategic insights and integrated solutions in a fast-paced healthcare environment while mentoring cross-functional teams towards operational excellence a...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.