Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$210K - $250K *

Join a dedicated team as you oversee comprehensive urologic services, ensuring quality patient care and administrative efficiency. Collaborate with interdisciplinary staff to enhance clinical practice...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$78K - $107K *

Manage and elevate clinical care standards and team performance, ensuring high-quality, resident-focused health services through compliance, assessment, and effective staffing to enhance overall welln...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$198K - $258K *

Lead the charge in defining and governing architectural strategies for a secure and scalable software ecosystem across device and digital platforms, influencing cross-functional teams and senior stake...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Healthcare

$173K - $310K *

Transform clinical outcomes by engaging with literature and experts; contribute 80-90% of time to editorial work while remaining clinically active. Utilize your medical expertise to produce evidence-b...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$85K - $100K *

Elevate your career by leading cross-functional projects, ensuring timely deliverables and driving process improvements through collaboration and expert project management methodologies...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$107K - $214K *

Optimize large-scale cybersecurity assessments and transformations, leading multidisciplinary teams to deliver measurable outcomes for complex clients. Drive strategic initiatives, manage risks, and b...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $100K *

Transform virtual learning by leading strategy and development of innovative programs. Collaborate across teams to enhance educational experiences, ensuring quality and scalability while meeting diver...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$125K - $145K *

Empower medical professionals by driving the adoption of innovative surgical technologies through strategic engagement, training, and market development, ensuring exceptional customer experiences and...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $145K *

Unlock potential by driving market adoption of cutting-edge spatial surgery technology. Collaborate with surgeons and stakeholders to enhance sales performance and exceed targets across defined region...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $145K *

Lead the charge in advancing spatial surgery commercialization through strategic market development, sales execution, and robust customer engagement, ensuring impactful adoption and utilization throug...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$74K - $90K *

Drive exceptional patient care as a Home Health RN Case Manager, providing skilled nursing, assessments, and education to promote independence while collaborating with a dedicated care team to ensure...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Empower your career by joining a collaborative physiatry team, where your skills will enhance patient rehabilitation and independence through comprehensive treatment plans and multidisciplinary collab...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Support a dynamic physiatry team by delivering patient-centered care, conducting assessments, and collaborating on treatment plans to enhance rehabilitation outcomes and promote independence for diver...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$68K - $103K *

Empower patient care by performing CT scans and assisting in procedures. Ensure quality imaging, maintain safety standards, and provide exceptional support to patients and medical staff in a dynamic h...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $118K *

Drive excellence in patient care by utilizing your RN expertise in a dynamic emergency department. Collaborate with a dedicated team to enhance patient outcomes and uphold safety standards while manag...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $159K *

Join us to foster an innovative educational environment, providing leadership and mentorship while enhancing curriculum and teaching methodologies to ensure student success and engagement in learning...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $185K *

Transform patient outcomes by leading psychometric research efforts, guiding strategic design and analysis of clinical assessments, and driving innovation within interdisciplinary teams committed to a...

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $185K *

Pioneer innovative psychometric approaches in interdisciplinary teams to enhance clinical outcome assessments. Lead research strategies, design robust analyses, and effectively communicate results to...

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Provide strategic scientific leadership in psychometric and outcomes research, guiding clinical outcome assessments and supporting regulatory interactions. Leverage statistical analyses and communicat...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$136K - $170K *

Partner with us to enhance patient access by leading market access strategies, educating teams, and collaborating across departments to ensure effective reimbursement for our innovative medical techno...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $153K *

Lead the successful deployment of IoT solutions for enterprise customers, ensuring they maximize the value of our technology throughout their lifecycle while collaborating with cross-functional teams...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Bring your expertise to a dynamic role where you'll shape marketing strategies and positioning for academic programs, ensuring clarity and effectiveness throughout their lifecycle while collaborating...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $130K *

Shape the future of mental health care by providing virtual counseling and developing treatment plans for patients with acute conditions. Collaborate with medical professionals while ensuring adherenc...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Technical Services

$190K - $225K *

Join a team that's shaping strategies to engage key opinion leaders in rare neurological diseases, driving insights and facilitating impactful relationships to inform brand evolution and support launc...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Join a dynamic team to lead strategic and operational initiatives in radiology, enhancing patient access and service quality while driving financial performance and team development across multiple lo...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.