Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Nurse Practitioner OR Physician Assistant
$90K - $110K *
Manage primary medical care within an occupational health program, ensuring quality patient management, diagnostic testing, and therapeutic procedures while collaborating with healthcare professionals...
3 weeks ago
$85K - $95K *
Design engaging multimedia content that embodies brand consistency across various formats, from print to digital. Collaborate with teams to create compelling visuals, animations, and videos that reson...
1 week ago
Medical Director (Publications)
$130K - $150K *
Champion effective publication strategies and lead scientific communication initiatives, acting as a strategic partner to clients and teams. Navigate complex medical affairs content to drive impactful...
Reposted 1 week ago
Senior Clinical Research Associate - Psychiatry(US, Central)
$97K - $193K *
Drive excellence in clinical research as a Senior CRA, ensuring quality and compliance throughout the study lifecycle. Collaborate with sites and teams to enhance patient safety and data integrity, in...
Reposted 3 days ago
$87K - $117K *
Lead the pediatric clinical program, ensuring safe transitions for medically complex children. Collaborate with families and healthcare teams to coordinate care, educate caregivers, and maintain clini...
3 weeks ago
PA or NP -Primary Care/Urgent Care Blend - MyCare 365 - Durham
$95K - $115K *
Engage in delivering comprehensive medical care as a Physician Assistant or Nurse Practitioner, collaborating with a multidisciplinary team to enhance patient outcomes in both inpatient and outpatient...
1 week ago
Territory Manager- University Partnerships
$120K *
Transform mental health care by building strategic partnerships with providers to enhance access to specialized OCD treatment. Drive growth through relationship-building, education, and effective refe...
2 weeks ago
Managing Consultant - Revenue Cycle - Healthcare
$120K - $165K *
Transform your career by leading revenue cycle consulting projects, managing junior staff, and driving operational improvements while building strong client relationships. Leverage your expertise in h...
1 month ago
Audit Policy Analyst, Post-Acute Services
$80K - $95K *
Innovate post-acute payment integrity by developing and optimizing audit concepts for DME, home health, and infusion therapy claims. Collaborate cross-functionally to ensure compliance and enhance ope...
3 days ago
Occupational Therapist, Hand Therapy
$79K - $118K *
Bring your expertise to a collaborative team dedicated to delivering outstanding patient care. Drive quality outcomes while providing treatment assessments and developing effective patient plans in a...
Reposted 3 weeks ago
Regional Director, Clinical Sales - Central
$150K - $180K *
Transform the clinical sales landscape by leading a regional team to drive utilization growth, enhance patient treatment metrics, and foster cross-functional collaboration for commercial success in in...
3 weeks ago
RVP, Solution Engineering - Mid-Market/Commercial
$210K - $322K *
Join a dynamic team to lead and empower Solutions Engineers, driving technical sales excellence while fostering collaborative innovation and ensuring customer success through strategic insights and re...
3 weeks ago
$110K - $130K *
Innovate by developing scalable applications and data pipelines, leveraging Python and cloud platforms. Collaborate with cross-functional teams to modernize enterprise systems and enhance backend serv...
1 week ago
HIM Outpatient Coding Supervisor
$68K - $113K *
Lead the charge in optimizing coding accuracy and compliance by analyzing complex patient care documentation, providing expert guidance, and enhancing coder education to ensure adherence to ethical st...
3 weeks ago
$168K - $231K *
Join a dynamic team to lead Nurse Case Managers, enhancing patient support and education throughout treatment journeys while ensuring compliance and quality in case management processes...
2 days ago
Associate Vice President - Early Development Clinical Research Physician - Neuroscience
$268K - $466K *
Champion early clinical development in a dynamic team. Lead clinical research physician role for first-in-human studies, ensuring compliance and collaboration across scientific and regulatory areas to...
3 weeks ago
Pharmacist (CPP) - Advanced Clinical Therapeutics
$115K - $165K *
Advance patient care by leading a pharmacist-led program focused on specialty therapeutics. Collaborate with healthcare teams to optimize medication management, enhance patient outcomes, and provide e...
1 week ago
$92K - $110K *
Deliver strategic leadership and operational oversight to enhance decision-making processes within the Veterans Health Administration's EHRM, ensuring effective collaboration and communication across...
1 week ago
Senior Security Consultant, Operational Technologies (OT)
$100K - $175K *
Grow expertise in Operational Technology security, leading critical engagements across industrial systems. Collaborate on advanced methodologies while mentoring others and contributing to pivotal rese...
Reposted 2 weeks ago
Neuroradiologist | Build Your Own Schedule | Remote, Hybrid & Onsite | Austin, TX
$400K - $500K+*
Drive advanced neuroradiology practices in a 100% remote role, collaborating with top specialists while maintaining work-life balance. Enjoy a supportive physician-led environment focused on clinical...
Reposted 2 days ago
Physician Assistant (Bilingual (Spanish))
$85K - $100K *
Join a dynamic team to provide comprehensive patient care in a busy outpatient setting. Engage in primary, urgent, and pain management services while building strong patient relationships and ensuring...
4 days ago
Physician Assistant (Bilingual (Spanish))
$85K - $100K *
Elevate your career by joining a dynamic team providing comprehensive patient care, including primary, urgent, and pain management services. Collaborate with esteemed providers in a modern outpatient...
5 days ago
$80K - $95K *
Oversee the resolution of complex technical issues, mentor analysts, and drive continuous improvement initiatives to enhance service reliability and user experience within the service desk environment...
3 weeks ago
$120K - $147K *
Shape your career by leading data integration initiatives that drive enterprise-wide consistency and governance. Collaborate with stakeholders to deliver trusted, scalable data products while ensuring...
2 days ago
$170K - $190K *
Shape the future of our technology landscape by architecting scalable, secure systems that empower a high-growth environment through innovative SaaS and AI strategies. Lead the implementation of best...
3 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.