Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Associate Director of Clinic Operations
$88K - $105K *
Join us to oversee daily operations of multiple clinics, ensuring efficient service delivery and excellent patient care. Collaborate with management and staff to optimize strategies and maintain compl...
2 weeks ago
Senior Scientific Director (Rare/Neurology/Psychiatry)
$150K - $180K *
Lead the charge in developing and overseeing scientific content across multiple therapeutic areas, ensuring high-quality contributions and strategic client interactions to drive growth and innovation...
3 weeks ago
Territory Vice President, Central
$170K - $200K *
Reimagine retail leadership as you drive sales growth and develop talent across multiple regions. Lead a team of Regional Directors to enhance patient relationships and execute strategic initiatives...
Yesterday
Area Medical Director - Oncology
$250K - $360K *
Lead the charge in advancing oncology diagnostics by engaging community oncologists, driving medical strategy, and executing initiatives across a defined region in this impactful, field-based leadersh...
3 weeks ago
$160K - $200K *
Shape the future of organizational strategy and performance excellence. Lead enterprise-wide initiatives, drive innovation, and ensure alignment with long-term goals while collaborating with executive...
3 weeks ago
$160K - $200K *
Join us to lead strategic initiatives that drive organizational excellence and growth. As a key advisor, you'll shape the future by identifying opportunities, fostering innovation, and ensuring alignm...
3 weeks ago
$160K - $200K *
Drive strategic vision and organizational excellence as a key advisor, shaping long-term growth initiatives and performance management. Collaborate with leadership to translate complex challenges into...
3 weeks ago
21GRAMS- Associate Medical Strategy Director
$120K - $135K *
Join a team that shapes innovative medical strategies, driving excellence in healthcare content. Collaborate with experts, cultivate client relationships, and inspire teams to elevate project outcomes...
Reposted 1 week ago
$111K - $150K *
Transform product strategy and execution by leveraging data insights, leading cross-functional teams, and prioritizing customer needs to drive product success and business growth in a dynamic environm...
2 weeks ago
Nurse Practitioner/Physician Assistant: Duke Neurosurgery - Complex Spine
$95K - $115K *
Join a team that's dedicated to providing exceptional patient care in neurosurgery. Collaborate with physicians and advanced practice providers to treat neurological and spinal disorders, ensuring qua...
2 weeks ago
Director of Health and Wellness
$80K - $95K *
Empower residents' well-being by leading clinical care in a senior living community. Manage teams, ensure compliance with regulations, and optimize health services to enhance quality of life for senio...
3 weeks ago
$92K - $110K *
Unlock potential by designing innovative plumbing systems for diverse projects. Collaborate across disciplines to create detailed construction documents and ensure compliance with industry standards w...
1 week ago
$92K - $110K *
Lead the charge in innovative plumbing design, delivering comprehensive solutions across diverse sectors, including healthcare and commercial. Collaborate with multidisciplinary teams to create effici...
1 week ago
$80K - $95K *
Unlock potential by driving network operations excellence for government clients. Engage in troubleshooting WAN issues, managing service requests, and enhancing vendor relationships while maintaining...
3 weeks ago
Licensed Clinical Social Worker Supervisor - Outpatient (LCSW, LCMHC, LMFT)
$70K - $115K *
Join a team that's dedicated to providing exceptional mental health care. As a Licensed Therapist, you'll support diverse populations, lead clinical initiatives, and enjoy a flexible work environment...
3 weeks ago
Director, Neurology - Thought Leader Liaison (SOUTH)
$245K - $265K *
Drive strategic partnerships with Medical Experts in neurology, enhancing patient care through insights and collaboration. This field-based role requires strong relationship-building and cross-functio...
1 week ago
Senior Financial Transformation Consultant
$98K - $163K *
Drive your career forward by transforming financial management processes, enhancing operational efficiency, and collaborating with senior stakeholders to implement innovative solutions in a dynamic co...
3 days ago
Associate General Counsel - Clinical & Commercial - CRO Services
$170K - $200K *
Unlock potential by providing strategic legal counsel on clinical and commercial operations, focusing on regulatory compliance, privacy, and data protection in a dynamic biopharmaceutical environment...
Reposted today
$140K - $170K *
Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...
2 weeks ago
Head of Rare Disease Patient Engagement
$206K - $283K *
Drive the future of patient engagement in rare diseases by leading innovative strategies that enhance access, adherence, and overall patient experience across a complex healthcare landscape, ensuring...
2 weeks ago
VP of Client Management; O500 (Hybrid; Carolinas)
$150K - $180K *
Drive client success and growth by leading high-performing teams, enhancing relationships, and executing strategic initiatives. Collaborate with executives to translate vision into impactful results w...
1 week ago
VP of Client Management; O500 (Hybrid; Carolinas)
$150K - $180K *
Advance client partnerships by driving growth and leading high-performing teams. You'll translate strategy into results while fostering collaboration and innovation, ensuring strong client retention a...
1 week ago
$95K - $115K *
Unlock potential by managing and optimizing project-level agreements, ensuring compliance and efficiency in contracting processes while supporting global operations and client needs in a dynamic legal...
1 week ago
Senior Strategic Implementation Consultant
$109K - $165K *
Build strong relationships at a leading IoT company, guiding enterprise customers through deployment and adoption of innovative solutions. Collaborate cross-functionally while driving customer success...
Reposted 3 weeks ago
Senior Specialist, Regulatory Operations
$122K - $143K *
Innovate regulatory operations by managing submission preparation and execution, ensuring compliance with FDA and ICH standards. Collaborate cross-functionally to support complex filings and maintain...
Yesterday
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.