Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$88K - $105K *

Join us to oversee daily operations of multiple clinics, ensuring efficient service delivery and excellent patient care. Collaborate with management and staff to optimize strategies and maintain compl...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Lead the charge in developing and overseeing scientific content across multiple therapeutic areas, ensuring high-quality contributions and strategic client interactions to drive growth and innovation...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$170K - $200K *

Reimagine retail leadership as you drive sales growth and develop talent across multiple regions. Lead a team of Regional Directors to enhance patient relationships and execute strategic initiatives...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$250K - $360K *

Lead the charge in advancing oncology diagnostics by engaging community oncologists, driving medical strategy, and executing initiatives across a defined region in this impactful, field-based leadersh...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Shape the future of organizational strategy and performance excellence. Lead enterprise-wide initiatives, drive innovation, and ensure alignment with long-term goals while collaborating with executive...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Join us to lead strategic initiatives that drive organizational excellence and growth. As a key advisor, you'll shape the future by identifying opportunities, fostering innovation, and ensuring alignm...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Drive strategic vision and organizational excellence as a key advisor, shaping long-term growth initiatives and performance management. Collaborate with leadership to translate complex challenges into...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $135K *

Join a team that shapes innovative medical strategies, driving excellence in healthcare content. Collaborate with experts, cultivate client relationships, and inspire teams to elevate project outcomes...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$111K - $150K *

Transform product strategy and execution by leveraging data insights, leading cross-functional teams, and prioritizing customer needs to drive product success and business growth in a dynamic environm...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to providing exceptional patient care in neurosurgery. Collaborate with physicians and advanced practice providers to treat neurological and spinal disorders, ensuring qua...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Empower residents' well-being by leading clinical care in a senior living community. Manage teams, ensure compliance with regulations, and optimize health services to enhance quality of life for senio...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$92K - $110K *

Unlock potential by designing innovative plumbing systems for diverse projects. Collaborate across disciplines to create detailed construction documents and ensure compliance with industry standards w...

1 week ago

  •   11 - 15 years exp.  •   Technical Services

$92K - $110K *

Lead the charge in innovative plumbing design, delivering comprehensive solutions across diverse sectors, including healthcare and commercial. Collaborate with multidisciplinary teams to create effici...

1 week ago

  •   11 - 15 years exp.  •   Technical Services

$80K - $95K *

Unlock potential by driving network operations excellence for government clients. Engage in troubleshooting WAN issues, managing service requests, and enhancing vendor relationships while maintaining...

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$70K - $115K *

Join a team that's dedicated to providing exceptional mental health care. As a Licensed Therapist, you'll support diverse populations, lead clinical initiatives, and enjoy a flexible work environment...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$245K - $265K *

Drive strategic partnerships with Medical Experts in neurology, enhancing patient care through insights and collaboration. This field-based role requires strong relationship-building and cross-functio...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$98K - $163K *

Drive your career forward by transforming financial management processes, enhancing operational efficiency, and collaborating with senior stakeholders to implement innovative solutions in a dynamic co...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$170K - $200K *

Unlock potential by providing strategic legal counsel on clinical and commercial operations, focusing on regulatory compliance, privacy, and data protection in a dynamic biopharmaceutical environment...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Healthcare

$140K - $170K *

Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$206K - $283K *

Drive the future of patient engagement in rare diseases by leading innovative strategies that enhance access, adherence, and overall patient experience across a complex healthcare landscape, ensuring...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive client success and growth by leading high-performing teams, enhancing relationships, and executing strategic initiatives. Collaborate with executives to translate vision into impactful results w...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Advance client partnerships by driving growth and leading high-performing teams. You'll translate strategy into results while fostering collaboration and innovation, ensuring strong client retention a...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Unlock potential by managing and optimizing project-level agreements, ensuring compliance and efficiency in contracting processes while supporting global operations and client needs in a dynamic legal...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$109K - $165K *

Build strong relationships at a leading IoT company, guiding enterprise customers through deployment and adoption of innovative solutions. Collaborate cross-functionally while driving customer success...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$122K - $143K *

Innovate regulatory operations by managing submission preparation and execution, ensuring compliance with FDA and ICH standards. Collaborate cross-functionally to support complex filings and maintain...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.