Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$160K - $200K *

Shape your career by launching and leading a transformative healthcare consulting practice. Drive growth through strategic engagements, build a robust team, and establish innovative solutions in data...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$90K *

Engage with healthcare professionals to drive growth in advanced wound care. Collaborate with cross-functional teams to develop strategies, expand accounts, and build strong relationships, ensuring ef...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $93K *

Join a dynamic team providing essential behavioral health support, addressing member needs through personalized interventions, referrals, and collaborative care to enhance overall mental health and we...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Join a team that's dedicated to providing exceptional urgent care services. Collaborate with a multidisciplinary team to treat patients of all ages, ensuring quality care in a fast-paced, walk-in clin...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Champion the delivery of high-quality nursing care by overseeing staff, ensuring compliance with regulations, and managing resources effectively to enhance patient outcomes in a dynamic health center...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$79K - $118K *

Lead a dedicated team in delivering high-quality respiratory care, ensuring compliance with clinical standards while fostering staff development and patient support. Drive departmental goals and enhan...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$136K - $187K *

Lead patient education and support initiatives for individuals affected by generalized Myasthenia Gravis. Collaborate with caregivers and healthcare teams to enhance treatment coordination and empower...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join our Clinical Science team to enhance data integrity in CNS trials by conducting meticulous reviews of clinical interviews, ensuring protocol compliance, and guiding site interventions as a Clinic...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$71K - $142K *

Champion the successful implementation of RTSM systems, ensuring timely delivery and adherence to client requirements while managing project budgets and communications throughout the project lifecycle...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Inspire excellence by leading a dedicated team in delivering high-quality ABA therapy. Oversee clinical operations, mentor staff, and ensure individualized care for clients with autism, fostering a co...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Drive client engagement and revenue growth by becoming a trusted advisor in Revenue Cycle Management. Leverage expertise to retain and expand business while ensuring client satisfaction across a diver...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Elevate healthcare reimbursement processes by leading legal strategies on billing disputes and regulatory compliance. Collaborate with teams to create innovative solutions and build legal frameworks t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$246K - $332K *

Transform healthcare by leading national strategic account management efforts. Drive partnerships with key institutions, enhance patient care, and foster cross-functional collaboration to achieve comm...

RemoteRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$250K - $325K *

Unlock the potential of age-friendly health systems by providing strategic clinical leadership and guidance. Collaborate with health systems to implement the 4Ms framework, driving improvements in car...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Join a team that's transforming healthcare operations through AI and automation. Collaborate with providers to improve patient outcomes, streamline workflows, and drive digital transformation initiati...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$93K - $101K *

Empower individuals by providing exceptional, client-focused care in a supportive environment. Collaborate with a passionate team while enjoying generous benefits and opportunities for professional gr...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$98K - $115K *

Lead the charge in delivering exceptional therapeutic outcomes for children with autism. Join a dedicated team, providing personalized care and collaboration in a supportive workplace committed to cli...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$98K - $115K *

Join a team that's dedicated to providing personalized care, fostering collaboration, and cultivating leadership in a supportive environment focused on enriching the lives of children with autism and...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Elevate patient care by providing comprehensive assessments and treatments in a dynamic outpatient setting. Collaborate with a dedicated team to enhance patient relationships and ensure continuity of...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Join a team that's dedicated to delivering exceptional patient care in a dynamic outpatient setting. Leverage your skills in primary, urgent, and pain management services while collaborating with este...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $135K *

Lead the charge in developing and managing enterprise proposals and plans, ensuring compliance and quality across submissions. Collaborate with cross-functional teams to enhance win strategies and dri...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $151K *

Champion operational excellence by ensuring radiation safety and EHS compliance across cyclotron manufacturing and PET nuclear pharmacy facilities in the South Central US, while collaborating with cro...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$233K - $263K *

Drive patient-centered care by managing diverse patient needs, conducting in-office and telehealth visits, and collaborating with clinical teams. Supervise NP or PA colleagues while engaging in contin...

Raleigh, NCRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$233K - $263K *

Join a team that's dedicated to delivering comprehensive patient care, managing diverse health needs, and collaborating with clinical teams. Engage in continuous learning and utilize your training to...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$230K - $275K *

Lead the charge in vulnerability research and exploitation techniques, transforming real-world threats into automated solutions. Collaborate with teams to enhance security measures and validate defens...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.