Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Senior Clinic Director- Phase I CRU, Remote US and Canada
$170K - $220K *
Elevate your career by managing clinical operations across multiple sites, ensuring performance excellence and strategic partnerships. Lead initiatives that drive growth, enhance client relationships...
1 week ago
RVP, Enterprise Sales - Northeast
$231K - $363K *
Grow your career with a dynamic sales role focused on building enterprise partnerships. Drive impactful healthcare solutions by engaging with HR leaders and managing the full sales cycle across the No...
2 weeks ago
$225K - $250K *
Transform operations by leading a diverse team to enhance profitability and efficiency across multiple sites, while building strategic relationships with clients and driving growth initiatives in the...
2 days ago
Nurse Practitioner OR Physician Assistant
$90K - $110K *
Transform your career by providing primary medical direction and care within an occupational health program. Collaborate with a team to deliver exceptional patient experiences while ensuring quality a...
4 days ago
Speech Language Pathologist (SLP)
$79K - $110K *
Transform lives by providing compassionate speech therapy to seniors. Collaborate with a dedicated team to evaluate, treat, and develop personalized care plans, ensuring each patient receives the atte...
Yesterday
High Reliability & Operational Transformation Consultant
$165K - $200K *
Innovate and drive operational excellence by delivering High Reliability and Human Performance transformations that boost organizational effectiveness and resilience across various complex environment...
Reposted 2 weeks ago
Behavioral Health Virtual Preceptor - Nurse Practitioner or Physician Assistant
$100K - $120K *
Unlock potential by mentoring new providers through virtual education, ensuring a seamless onboarding experience. Leverage your clinical expertise to foster growth in both primary care and behavioral...
1 week ago
$136K - $187K *
Unlock potential by serving as a vital resource for patients and caregivers, providing education and support for managing generalized Myasthenia Gravis while coordinating treatment and navigating insu...
Yesterday
Senior Engineer, Unified Communications
$87K - $117K *
Unlock potential by leading the design, deployment, and support of Unified Communications platforms, ensuring optimal performance and compliance while collaborating with vendors and teams to manage la...
4 weeks ago
$80K - $95K *
Join a team that's dedicated to enhancing patient safety through data analysis, audits, and collaboration across departments. Drive improvements in EHR software and support quality initiatives to ensu...
3 days ago
LMFT / LCSW / LPCC / PsyD | Remote Mental Health Therapist | Nationwide
$150K - $200K *
Transform lives by providing virtual therapy and developing personalized treatment plans. Collaborate with a dedicated team to deliver compassionate, evidence-based care while enjoying the flexibility...
2 weeks ago
Telehealth Physician - Remote, US
$180K - $220K *
Transform the future of care navigation by leading clinical evaluations and developing protocols in a telehealth setting, guiding team efforts to ensure high-quality, patient-centered care for complex...
3 weeks ago
California Collaborating Psychiatrist (Clinical & Supervisory Role)
$210K - $250K *
Join a dynamic mental health team as a Collaborating Psychiatrist, providing clinical oversight and direct patient care. Engage in meaningful collaboration with PMHNPs while ensuring compliance and de...
1 week ago
Medical Education Design & Practice Leader
$150K - $200K *
Lead the charge in shaping medical education design globally, driving strategy and growth while collaborating with multidisciplinary teams to enhance learning environments and expand institutional par...
1 week ago
Medical Education Design & Practice Leader
$150K - $200K *
Shape the future of medical education by leading strategic planning and design initiatives. Drive national and international growth while collaborating with multidisciplinary teams to enhance learning...
1 week ago
21GRAMS- VP, Medical Strategy Director
$180K - $195K *
Elevate healthcare marketing by transforming complex science into impactful strategies. Lead multidisciplinary teams to inspire creativity, drive behavior change, and build trusted client relationship...
Reposted 1 week ago
Nurse Practitioner/Physician Assistant - Duke Neurosurgery FUNCTIONAL
$95K - $115K *
Take ownership of patient care in the neurosurgery department by providing advanced clinical support to enhance patient outcomes. Collaborate with supervising physicians to deliver diagnostic, therape...
Reposted 3 days ago
Sr. Medical Director, Rheumatology - US Remote
$173K - $320K *
Shape the future of rheumatology by providing strategic medical oversight across clinical trials. Lead the innovation and development of groundbreaking therapies while collaborating with multidiscipli...
Reposted 1 week ago
Vice President - Enterprise Applications
$163K - $218K *
Lead the strategy and delivery of enterprise applications, optimizing technology platforms to enhance clinical care and business operations. Collaborate with cross-functional teams to drive improvemen...
1 week ago
$80K - $121K *
Lead impactful training initiatives designed to empower customers globally. Utilize innovative methods and foster strong relationships to enhance learning experiences and drive success across diverse...
Reposted 3 weeks ago
$175K - $210K *
Lead the charge in driving enterprise growth within healthcare by building relationships with national and regional health plans. Own new logo acquisition and expansion, leveraging a robust support sy...
4 days ago
Remote Clinical Psychologist - Older Adults | PhD / PsyD | PSYPACT | Telehealth
$100K - $120K *
Join a supportive team delivering evidence-based psychotherapy to older adults. Enjoy flexible scheduling, comprehensive admin support, and opportunities for professional growth while making a meaning...
1 week ago
$88K - $140K *
Shape the future of public service by leading technology consulting projects that enhance operational efficiency and strategic goals for state and local agencies, ensuring compliance and delivering im...
1 week ago
Provider Clinical Operations Consultant, Manager
$99K - $232K *
Engage in transformative provider clinical operations, leading teams to enhance healthcare delivery through innovative solutions, process improvements, and strategic client engagements in a dynamic he...
1 week ago
Vice President, Business Development
$210K - $250K *
Lead strategic business development initiatives, driving deal execution and relationship management with senior health plan stakeholders. Shape growth strategies and negotiate value-based care contrac...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.