Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$86K - $118K *

Design and deliver engaging user experiences for medical benefits, leveraging user-centered principles and collaboration to enhance member satisfaction and streamline healthcare navigation. Shape impa...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $215K *

Unlock regional growth by leading a high-performing sales team, executing launch strategies, and fostering key customer relationships in a dynamic, fast-paced environment. Drive performance and ensure...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$72K - $89K *

Join a dynamic Early Intervention team to deliver impactful OT services for children (birth-3 years) with developmental delays. Collaborate with families and professionals to foster growth in natural...

Today

  •   Less than 5 years exp.  •   Healthcare

$121K - $161K *

Transform your career by leading the design and implementation of Veeva Vault RIM, ensuring optimal performance and compliance while collaborating with cross-functional teams to enhance user experienc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$155K - $210K *

Drive success by championing patient needs and executing strategic account plans. Leverage clinical expertise and business acumen to exceed sales goals while fostering relationships with key stakehold...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dynamic team where you'll take ownership of key Corporate Performance Management projects, executing tasks from build to testing, while collaborating with clients and delivering high-quality wo...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$127K - $160K *

Advance your career by joining a dynamic team in urgent care, providing essential services across multiple locations. Enjoy a supportive environment with strong collaboration and a predictable schedul...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$94K - $151K *

Innovate your career by leading penetration testing services programs that enhance the security of medical devices and applications, ensuring safety and compliance through robust testing methodologies...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Engage in operational and clinical oversight to enhance Respiratory services, ensuring high-quality, patient-centered care across multiple locations. Drive continuous improvement while fostering a col...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Shape the future of customer relationships by driving value and retention for large organizations, collaborating closely with sales and product teams to ensure success and growth through data-driven i...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$102K - $177K *

Lead the charge in developing innovative spine marketing strategies that drive growth and enhance patient care. Collaborate with cross-functional teams to create compelling campaigns that resonate wit...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$102K - $177K *

Pioneer innovative digital marketing strategies to enhance spine product campaigns. Collaborate with cross-functional teams to develop compelling messaging and content that drives engagement and suppo...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $145K *

Unlock potential by managing and optimizing IT operations across platforms and applications. Collaborate with teams to ensure security, reliability, and efficiency while developing scalable processes...

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $145K *

Join a team that's dedicated to maintaining secure, reliable IT operations. You'll manage platforms, troubleshoot applications, and enhance workflows, ensuring seamless support for internal teams whil...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the charge in developing global health, welfare, and wellbeing strategies that enhance employee engagement and performance. Collaborate with cross-functional teams to ensure compliance and local...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$92K - $153K *

Drive impactful data solutions by leveraging analytics and visualization tools. Collaborate with clients to enhance decision-making processes and optimize workflows, ensuring data-driven insights alig...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Business Services

$230K - $310K *

Shape the future of IT Infrastructure & Operations by leading strategy and delivery for rapid growth and innovation in a tech-driven environment, ensuring security, scalability, and support across mul...

RemoteRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Transportation

$150K - $180K *

Innovate data-driven strategies to enhance business decision-making and optimize reporting processes. Leverage expertise in BI, CRM Analytics, and Salesforce to deliver actionable insights and support...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $216K *

Engage with clients as a NERC CIP Subject Matter Expert, leading project workstreams and driving compliance solutions. Foster industry relationships and support business development to enhance client...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

$186K - $234K *

Grow your career by driving sales and building relationships in the neurology and rare disease sectors. Collaborate with healthcare professionals to enhance patient care and achieve sales targets whil...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$248K - $306K *

Lead a dynamic legal team, providing strategic counsel for R&D and Supply Chain. Collaborate with senior leaders to navigate complex legal issues, negotiate contracts, and drive risk-appropriate strat...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$122K - $176K *

Unlock your potential by joining a dynamic team focused on developing multiscale computational models to drive innovative drug discovery and development, leveraging deep biological insights and advanc...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Lead global field operations, driving strategy and execution across sales, technical services, and partner functions. Collaborate with senior leadership to optimize pipeline management, forecasting, a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$156K - $234K *

Drive transformation by leading client engagements, guiding teams to deliver actionable solutions, and fostering business growth through project development and mentoring. Make your mark by ensuring s...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform patient care as a Nurse Practitioner/Physician Assistant in an urgent care setting. Collaborate with physicians to deliver high-quality healthcare and exercise clinical expertise in a fast-p...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.