Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$125K *

Shape the future of assisted living by leading daily operations, ensuring high-quality services, and fostering a motivated team. Drive financial success while maintaining compliance and enhancing resi...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $90K *

Join a team that's dedicated to enhancing patient care through effective utilization review. Collaborate with healthcare professionals to ensure compliance and quality in mental health services while...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $206K *

Drive strategic risk management initiatives by leading regulatory audits, enhancing operational processes, and fostering cross-functional collaboration to minimize financial impacts and improve audit...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $100K *

Lead the clinical team to deliver exceptional care, fostering relationships with residents, families, and healthcare providers while mentoring staff and enhancing satisfaction in a dynamic healthcare...

Today

  •   Less than 5 years exp.  •   Healthcare

$213K - $240K *

Transform clinical development by leading statistical strategy for trials, ensuring quality deliverables and regulatory compliance while collaborating across functions in a dynamic biotech environment...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$359K - $431K *

Shape your career by leading the global medical strategy for a dynamic portfolio. Collaborate with cross-functional teams to drive evidence generation, stakeholder engagement, and strategic execution...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Transform financial operations by leading accounting, treasury, and payment processes. Ensure accuracy and integrity in financial reporting while enhancing systems and controls for scalable growth in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Elevate your career by supporting critical cybersecurity initiatives for the Air Force. Collaborate with a dynamic team to enhance system security, manage vulnerabilities, and ensure compliance in a f...

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$150K - $175K *

Lead the charge in delivering insights through advanced research and analysis, managing multiple projects, guiding team performance, and enhancing client relationships in the life sciences consulting...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion innovation in the medical device sector by providing expert product support, technical guidance, and collaborative solutions to enhance the U.S. sales and marketing efforts for a leading impl...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$185K - $210K *

Lead and optimize global technology services across Adobe and Salesforce ecosystems. Drive strategic direction, client delivery, and team growth in a fast-paced environment. Champion technical excelle...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$93K - $120K *

Advance your career by providing innovative DBT therapy via live video to diverse clients. Collaborate with a supportive team, enhance skills through continual learning, and impact lives with evidence...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$45K - $250K *

Transform your career by connecting healthcare professionals with meaningful roles. Join a supportive team focused on building relationships and driving results while enjoying unlimited earning potent...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $400K *

Transform the Americas sales strategy by leading a diverse team to drive revenue through new business, renewals, and expansions. Focus on building repeatable processes while leveraging insights and ef...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$97K - $141K *

Elevate your career by leading strategic physician recruitment efforts, collaborating with clinical leaders to attract top talent, and enhancing the candidate experience from sourcing to onboarding. D...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$333K - $450K *

Lead the charge in developing innovative clinical strategies to enhance patient safety and streamline Phase 2/3 programs, while collaborating with discovery teams and ensuring regulatory compliance in...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$142K - $195K *

Champion transformative enterprise architecture initiatives that align technology with business strategy, driving innovation and modernization across healthcare payer domains to enhance operational ef...

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Pioneer innovative AI solutions in healthcare, tackling ambiguous challenges directly. Collaborate with top experts, shipping impactful products at speed while taking full ownership of your work and d...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$275K - $330K *

Champion the strategic oversight of global clinical operations, ensuring timely execution and compliance of clinical trials. Lead and mentor a high-performing team while managing relationships with CR...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Drive scientific strategy and lead therapeutic programs in neurobiology, overseeing target validation to preclinical proof-of-concept. Collaborate with teams to identify novel targets and foster partn...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in developing interoperability specifications for Veteran health information exchange, collaborating with cross-functional teams to enhance standards and ensure compliance with federal...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$124K - $232K *

Empower your career with a pivotal role in developing innovative learning solutions for Global Operations, leveraging cutting-edge technologies and collaboration to enhance training effectiveness and...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$72K - $130K *

Join a team that's dedicated to diagnosing and treating hearing and balance disorders. You'll conduct assessments, develop treatment plans, and provide personalized care to patients of all ages in a s...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $183K *

Optimize health policy research by applying advanced quantitative methods to inform stakeholders. Collaborate on multidisciplinary teams to evaluate health care markets, coverage, and costs, deliverin...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$176K - $287K *

Champion the design and execution of hematology/oncology clinical studies, leading cross-functional teams to ensure data integrity and impactful outcomes in a dynamic, science-driven environment...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.