Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$135K - $170K *

Transform your career by leading hydrogeologic studies and water supply projects. Collaborate with teams, manage client relationships, and drive innovative solutions in groundwater science while ensur...

Yesterday

  •   11 - 15 years exp.  •   Technical Services

$80K - $95K *

Elevate quality assurance standards by developing and implementing effective QAPI programs. Collaborate with teams to identify improvement areas, conduct evaluations, and ensure compliance with health...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $189K *

Unlock potential by joining a dynamic team focused on advancing anti-obesity therapeutics through innovative cell culture and functional assays, collaborating across departments to drive impactful dru...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Lead the charge in advancing digital pathology through innovative image analysis and machine learning techniques, driving insights from complex datasets to enhance drug discovery and deepen understand...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Shape the future of healthcare technology by leading clinical strategy initiatives to enhance drug diversion prevention and ensure patient privacy compliance. Drive impactful relationships, educate st...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$290K *

Elevate your career by providing expert anesthesia care in diverse clinical settings. Collaborate with multidisciplinary teams to ensure patient safety and quality outcomes while engaging in education...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Transform healthcare delivery by providing emergency and primary care at remote worksites. Collaborate with clinical teams to ensure quality assurance and support field staff while maintaining essenti...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$87K - $97K *

Join a team that’s dedicated to providing exceptional care while impacting the lives of residents. Utilize your skills to oversee nursing activities and ensure quality care in a supportive, rewarding...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Unlock your potential by leading clinical reimbursement and compliance across a multi-site skilled nursing portfolio. Collaborate closely with clinical teams to optimize documentation, reimbursement s...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Engage with us to navigate complex legal landscapes and advise on strategic decisions in the pharmaceutical sector. Drive compliance and innovation as you partner with diverse teams to shape impactful...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $300K *

Drive product strategy and lifecycle management, ensuring alignment with market needs and business growth. Lead cross-functional teams to develop, launch, and support innovative medical devices while...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$130K - $160K *

Transform financial strategies by leveraging your expertise in analyses, forecasting, and IT governance. Drive impactful recommendations and enhance operational efficiency through innovative financial...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$143K - $291K *

Join a team that's dedicated to empowering healthcare professionals through innovative medical devices. Lead a high-performing sales organization, drive revenue growth, and enhance patient care with c...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$332K - $469K *

Drive strategic leadership in drug development, mentoring teams to optimize innovative therapies across diverse portfolios, ensuring alignment with business goals and fostering collaboration for impac...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Drive innovation in course design and implementation. Lead projects that enhance learning experiences and efficiency while collaborating with faculty and stakeholders in a rapidly evolving educational...

4 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$129K - $177K *

Elevate decision-making through advanced behavioral insights and causal inference. Lead a team to design measurement strategies, enhance operational investments, and drive impactful outcomes across en...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$132K - $165K *

Shape the future of billing and collections by driving product strategy and enhancing user experiences. Collaborate with cross-functional teams to deliver reliable payment solutions that boost revenue...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Deliver leadership and governance for global clinical study management, ensuring projects meet timelines and budgets while fostering collaboration and operational excellence across teams and stakehold...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $165K *

Elevate product strategy in women's health by leading lifecycle management, leveraging AI insights, and driving cross-functional collaboration to enhance portfolio performance and profitability...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a dynamic team to enhance decision-making and support EHRM initiatives. Drive program management, facilitate stakeholder engagement, and contribute to strategic communications while ensuring effe...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$217K - $281K *

Lead the charge in optimizing and expanding CrowdStrike Falcon engagements, delivering managed security services, and mentoring teams while acting as a trusted advisor to clients in the cybersecurity...

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$250K - $275K *

Join us to lead clinical operations for a multi-state virtual care team, ensuring high-quality, timely care. This role combines direct patient care, administrative leadership, and strategic oversight...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$100K - $165K *

Drive impactful product deployments by leading comprehensive customer interactions, defining configurations, and ensuring successful integration of conversational AI systems into clinical workflows fo...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$260K - $290K *

Lead strategic medical initiatives for Multiple System Atrophy, guiding cross-functional teams in the U.S. medical strategy, scientific communication, and external engagement, while ensuring complianc...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$97K - $152K *

Transform system-level engineering by leading integration, verification, and architecture efforts. Drive cross-functional collaboration to deliver robust, customer-focused solutions throughout the pro...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.