Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$95K - $100K *

Empower individuals by delivering expert speech-language therapy in diverse home settings. Collaborate with healthcare teams to evaluate and treat communication disorders, enhancing patient quality of...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $100K *

Unlock your potential by providing expert speech-language therapy in diverse home settings. Collaborate with healthcare professionals to enhance patient communication and quality of life for individua...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $100K *

Champion skilled speech-language therapy for individuals in home settings, evaluating and treating various communication disorders. Collaborate with healthcare teams to enhance patient outcomes and su...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$135K - $169K *

Drive excellence in patient care as you manage medication therapy for kidney, pancreas, and liver transplant patients. Collaborate with a multidisciplinary team to enhance clinical outcomes and lead e...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $110K *

Solve complex production challenges and ensure system stability as a key technical support resource. Collaborate cross-functionally to enhance customer satisfaction through effective incident manageme...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$168K - $272K *

Manage government partnerships by driving funding initiatives, building trusted relationships with programs like DARPA and ARPA-H, and shaping compelling narratives that connect groundbreaking science...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $125K *

Drive strategic growth and retention by managing key partnerships in the healthcare benefits ecosystem. Collaborate cross-functionally to enhance partner satisfaction and revenue while executing annua...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Drive solutions for employer benefit ecosystems by leading pre-sales efforts, analyzing client needs, and designing tailored implementations for optimal savings and member engagement, collaborating cl...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$139K - $213K *

Drive relationships and sales success by positioning technology solutions within the U.S. Army. Leverage existing networks and develop strategic accounts, ensuring a superior customer experience that...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Partner with us to bridge technical solutions and customer needs in a dynamic, cross-functional role. Utilize your expertise to drive adoption of AI agents, influencing product roadmaps and enhancing...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$82K - $90K *

Empower successful RHTP initiatives through stakeholder engagement, communications, and project support. Collaborate with diverse teams to ensure effective outreach, timely execution, and inclusive pa...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$93K - $174K *

Contribute to groundbreaking drug discovery by advancing disease biology understanding, collaborating with multidisciplinary teams, and utilizing histology techniques to support target identification...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead Corporate FP&A initiatives, driving budgeting, forecasting, and performance management. Oversee financial analysis and reporting while enhancing systems and dashboards for improved decision-makin...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$145K - $175K *

Take ownership of technology improvements and elevate project deliveries by leading design and architecture initiatives. Collaborate with teams to implement solutions that drive business success throu...

4 weeks ago

  •   8 - 10 years exp.  •   Business Services

$210K - $250K *

Innovate in AI-native primary care by leading a dynamic medical group. Manage physicians, enhance care delivery, and shape clinical programs while maintaining direct patient care involvement. Drive ex...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Join a team that's dedicated to enhancing patient care through comprehensive post-discharge support. As an Advanced Practice Provider, you'll manage complex cases, collaborate with interdisciplinary t...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $398K *

Drive impactful legal strategies in a global clinical research environment, guiding senior leadership on complex regulatory and compliance matters while fostering innovation and risk management across...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Help us drive innovative product strategies in patient services, focusing on access, adherence, and affordability. Lead cross-functional teams to translate business needs into impactful technology sol...

Massachusetts, USRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$226K - $310K *

Champion strategic legal initiatives through expert counsel in complex biotech transactions. Drive impactful negotiations and foster collaboration across teams to enhance organizational growth and inn...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$213K - $286K *

Drive regulatory CMC strategy and execution for biologics programs, ensuring high-quality submissions and compliance with global standards. Collaborate across teams to guide development strategy and i...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$321K - $500K+*

Join a team that's shaping the future of oncology by leading global clinical strategies for solid tumors. Drive innovation and collaboration across multiple programs while ensuring alignment with regu...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$72K - $101K *

Discover a rewarding opportunity as a Licensed Practical Nurse, overseeing resident care and coordinating nursing processes while ensuring compliance with regulations and standards in a supportive env...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$72K - $101K *

Contribute to exceptional patient care by overseeing nursing processes, ensuring compliance with regulations, and supervising staff. This role emphasizes collaboration and quality in a skilled nursing...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $155K *

Lead the charge in designing and launching innovative enterprise solutions for healthcare clients, enhancing consumer applications while ensuring compliance and security standards are met. Collaborate...

Today

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Launch operational efficiencies by bridging gaps between Engineering and Customer Experience. Diagnose complex issues, execute backend fixes, and enhance production support using AI and API technologi...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.