Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$125K - $150K *

Oversee a portfolio of clinical studies, ensuring compliance and quality. Lead Project Managers in executing complex trials, driving operational efficiency and client satisfaction while leveraging you...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $210K *

Partner with us to drive innovative financial solutions in the healthcare sector. Leverage your Workday expertise for impactful implementations, collaborating closely with teams to transform operation...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$92K - $138K *

Join a team that's enhancing clinical education and training for General Imaging Ultrasound, impacting patient care and workflow. Drive innovative strategies from pre-sale to post-implementation, ensu...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Transform healthcare delivery by leading operations for a growing telehealth practice. Collaborate with clinical teams to enhance patient care through innovative solutions and efficient workflows, ens...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive impactful IT project delivery in a multi-site healthcare environment. Lead complex transformations, enhance governance, and foster stakeholder collaboration while ensuring tangible business outc...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$97K - $135K *

Join a dedicated team as you provide preventive dental care and educate patients on oral hygiene. Play a key role in fostering healthier smiles while ensuring patient comfort and maintaining complianc...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$97K - $135K *

Transform patient care by providing preventive dental hygiene services, educating patients, and ensuring comfort. Join a dedicated team focused on enhancing smiles and delivering exceptional patient e...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$162K - $224K *

Drive growth in the Neurodegenerative Disease sector by developing strategic partnerships with health systems and academic centers, leveraging existing relationships to create innovative solutions tha...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$208K - $416K *

Explore a rewarding opportunity to deliver top-notch telemedicine care with flexible scheduling. Work alongside a supportive team to provide continuous primary care and leverage technology for seamles...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $150K *

Champion clinical project success by leading operations, training teams, and ensuring compliance. Drive strategic planning and risk management while overseeing site performance and fostering collabora...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Champion regulatory strategy and submissions for clinical-stage radiopharmaceutical programs. Collaborate cross-functionally to ensure compliance and quality in regulatory communications, while leadin...

Cambridge, MARemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$166K - $200K *

Champion regulatory excellence by leading cross-functional teams to ensure compliant submissions for clinical-stage radiopharmaceutical programs, driving strategic interactions with Health Authorities...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Transform the provider referral landscape by leading strategic growth initiatives, building key relationships, and enhancing outreach efforts to ensure a robust pipeline of patient referrals in a dyna...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Transform the communications landscape by building a dynamic team that drives brand relevance through strategic earned media, influencer relations, and corporate communications, ensuring a consumer-fi...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$90K - $100K *

Join a team that's passionate about transforming complex scientific data into engaging communications. Collaborate with cross-functional experts to deliver high-quality medical content and strategies...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $195K *

Lead the charge in shaping technical direction and mentoring teams while driving program delivery and fostering a culture of growth and collaboration in a dynamic engineering environment...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$180K - $210K *

Champion innovative AI and digital strategies through complex client engagements. Lead cross-functional teams, influencing executive stakeholders, and deliver impactful solutions that scale with effic...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $105K *

Join a team that's dedicated to optimizing the employee lifecycle, ensuring compliance and data integrity while enhancing operational efficiency. Collaborate cross-functionally to drive process improv...

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$126K - $210K *

Lead strategic initiatives to enhance referral growth and provider engagement across chronic therapy markets. Drive collaboration among cross-functional teams to optimize patient progression and deliv...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$75K - $95K *

Empower our genomic testing operations by ensuring accurate patient and billing information is collected and maintained. Serve as a vital liaison among patients, physicians, and lab staff to facilitat...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead the charge in operational excellence for a new clinic, driving service delivery and team development while collaborating across functions to enhance patient care and achieve key performance indic...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $215K *

Unlock potential by leading regional sales efforts for a groundbreaking product. Drive performance through strategic execution, team leadership, and customer engagement in a fast-paced, entrepreneuria...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$98K - $163K *

Elevate your career as a Senior Consultant, driving data management and analytics for pharma clients. Lead predictive modeling, automate workflows, and enhance team productivity while coaching data en...

Today

  •   Less than 5 years exp.  •   Business Services

$120K - $165K *

Drive the successful transfer of CDI best practices by mentoring client teams, conducting record reviews, and delivering education. Collaborate with healthcare professionals to enhance documentation a...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$134K - $162K *

Contribute to the advancement of medical physics by leading dosimetry analysis for radiopharmaceuticals. Collaborate with cross-functional teams to drive research in drug development and improve imagi...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.