Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$125K - $140K *

Lead the charge in managing strategic clinical programs and customer relationships. Drive adoption, optimize workflows, and ensure account growth while delivering measurable value and fostering collab...

Boston, MARemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$99K - $144K *

Join a team that's dedicated to enhancing patient safety through risk analysis, quality improvement, and collaborative initiatives. Lead efforts to foster a culture of safety and compliance within a d...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Contribute to impactful SaaS implementations, guiding clients through setup, data migration, and training while leading complex projects to success across municipal government sectors...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $150K *

Champion social strategy and community engagement, driving impactful growth across multiple channels. Lead a dynamic team to create culturally relevant content, leveraging AI for efficiency and innova...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$153K - $268K *

Join our team to provide expert clinical pharmacology insights, driving dose selection and study design for innovative therapies. Collaborate with cross-functional teams to translate complex data into...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $200K *

Drive strategic medical initiatives in Rare Neurology, collaborating with cross-functional teams to enhance patient outcomes. Leverage your expertise to shape launch strategies and foster relationship...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's focused on enhancing client delivery and relationship growth. Drive data-driven strategies and cross-functional collaboration to optimize post-sale operations, ensuring exceptional...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Drive the execution and oversight of clinical trials, ensuring high-quality data supports product strategy. Collaborate cross-functionally to manage clinical development programs, adhering to regulato...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$74K - $98K *

Elevate quality operations by leading corrective action plans (CAPs) for regulatory compliance. Collaborate with cross-functional teams to drive accountability, resolve barriers, and ensure sustained...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Shape the future of HR technology by managing and optimizing our HRIS. Serve as a vital expert, collaborating across departments to enhance system performance, streamline processes, and ensure data in...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$122K - $212K *

Join a dynamic team as a strategic leader in product communications, driving impactful narratives for the Trauma portfolio. Collaborate cross-functionally to enhance brand credibility and support busi...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Lead the charge in architecting innovative End User Computing solutions, collaborating with account teams and clients to drive strategy, deliver presentations, and enhance customer experiences while e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Lead the assessment and coordination of nursing practices across multiple units. Support the CNO in delivering high-quality patient care and resource management while ensuring staff competency and saf...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$195K - $341K *

Engage in clinical oversight and support staff training while ensuring adherence to quality standards and regulatory compliance in a collaborative healthcare environment focused on member care and ope...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $210K *

Champion scientific research initiatives by leading the Institute of Coaching's agenda, ensuring rigorous standards and relevance in all scholarly outputs and educational programs, while mentoring tra...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$83K - $99K *

Execute patient care duties by operating radiographic equipment to produce diagnostic imaging. Collaborate with a multi-disciplinary team while ensuring safety protocols and patient understanding thro...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Champion operational excellence in clinical trials by leading a team of Clinical Trial Managers. Drive strategic initiatives, ensure compliance, and enhance sponsor relationships while delivering stud...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Support patient evaluations by conducting psychological assessments and collaborating with a clinical team to enhance diagnostic outcomes and treatment plans. Leverage expertise in standardized testin...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$107K - $150K *

Engage with clients to design and implement advanced Physical Security Systems. Collaborate with top engineers on complex projects, ensuring high-quality solutions and customer satisfaction while mana...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $90K *

Deliver high-quality clinical care by assessing, planning, and implementing patient care while supervising staff. Ensure safety, quality, and resource management in a dynamic healthcare environment, s...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $215K *

Elevate regional sales performance by leading a high-impact team, executing strategic launches, and fostering key customer relationships in a dynamic, fast-paced environment. Drive accountability and...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead the charge in defining systems engineering strategy and architecture for complex medical devices, ensuring alignment with customer needs and regulatory standards while driving innovation and engi...

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$135K - $173K *

Transform patient care by leading preoperative assessments and evaluations. Collaborate with multidisciplinary teams to enhance surgical outcomes and ensure seamless perioperative experiences in a str...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Advance strategic marketing and business development initiatives, overseeing sales and customer service efforts. Foster relationships and implement comprehensive strategies to drive growth and revenue...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Unlock potential by delivering comprehensive care to diverse patients, collaborating with healthcare teams, and promoting health education. Join a dynamic environment focused on innovation and persona...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.