Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$330K - $390K *

Join a team that's driving enterprise-level strategic statistical leadership across Biostatistics. You'll oversee programs, mentor statisitians, and ensure collaboration for successful drug developmen...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$245K - $270K *

Unlock potential by leading safety strategy and risk management across clinical development programs, utilizing robust data sources to ensure patient safety and compliance with global regulations whil...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the clinical department, managing operations and staff to ensure high-quality home health care. Drive performance improvements and compliance while fostering a supportive environment for clinicia...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform virtual primary care by delivering exceptional patient care in a collaborative environment. Join a dedicated team for a 5-month full-time opportunity, enhancing your skills while making a me...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Partner with us to drive sales in the Neurosurgery product line, achieving revenue targets through strategic planning, relationship building, and exceptional customer service in a dynamic operating ro...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$205K - $247K *

Unlock your potential by leading HEOR and RWE strategies for neurology assets. Collaborate with cross-functional teams to generate evidence that demonstrates the value of innovative therapies, support...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$300K - $373K *

Optimize your practice by focusing on patient care while enjoying flexible scheduling and collaboration with a supportive team. Benefit from ongoing learning opportunities and a personalized caseload...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $145K *

Join a dynamic team supporting middle school students with diverse speech needs. Provide therapy, develop individualized plans, and collaborate with educators to enhance student communication skills a...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$122K - $212K *

Elevate your career by leading the US Spine supply chain operations, driving inventory optimization and asset efficiency while fostering a culture of data-driven decision-making and team development i...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$114K - $187K *

Empower patient safety initiatives by leading safety data analysis and risk assessment for clinical and post-marketing phases. Collaborate with cross-functional teams to enhance safety strategies and...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$156K - $234K *

Shape the future of healthcare technology by guiding enterprise architecture, ensuring alignment with business priorities, and fostering innovation through strategic collaboration and governance...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $100K *

Take ownership of complex desktop and mobile device support, ensuring high customer satisfaction. Administer enterprise management platforms and collaborate with teams to deliver effective technology...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Transform endpoint management by leading complex support initiatives, ensuring seamless service delivery across diverse environments. Collaborate with teams to enhance user experience and optimize tec...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$98K - $102K *

Innovate transformative ABA services for children with autism, leading clinical excellence and mentorship. Drive program development and collaboration with educators and families to enhance individual...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$114K - $156K *

Elevate patient care as a Nurse Practitioner, conducting evaluations, developing treatment plans, and prescribing medications in a collaborative outpatient setting focused on opioid recovery. Join us...

Today

  •   Less than 5 years exp.  •   Healthcare

$66K - $96K *

Lead a specialized care management program to enhance health outcomes for multi-visit patients. Collaborate with diverse teams to address clinical and social needs, while supervising students and enga...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$73K - $183K *

Reimagine client solutions by delivering high-quality development and analysis. Collaborate with teams to meet client satisfaction objectives while managing complex projects and ensuring technical qua...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Shape the future of recruitment by building a market strategy, developing client relationships, and managing the full recruitment lifecycle to drive success and revenue growth in a dynamic environment...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Staffing

$85K *

Advance your career in small animal surgery through a hands-on residency program. Collaborate with board-certified surgeons, manage diverse surgical cases, and enhance your clinical skills in a suppor...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$115K - $140K *

Join a team that's shaping compelling narratives across diverse marketing channels. You'll craft engaging copy for digital ads, emails, and more, collaborating closely with various departments to enha...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$250K - $350K *

Empower enterprise clients by leading executive technology strategy, driving transformation initiatives that connect business priorities with major technology shifts, and building long-term, trust-bas...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$223K - $313K *

Collaborate with a dedicated team of physicians to ensure high-quality inpatient care through clinical expertise, thorough reviews, and utilization management. Advance patient outcomes by utilizing st...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$97K - $118K *

Empower residents by delivering compassionate nursing care and support. Collaborate with interdisciplinary teams to enhance the health, well-being, and independence of seniors while performing essenti...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $160K *

Analyze complex data and drive solutions as a Business Analyst in the public sector. Leverage your expertise in pension systems to identify issues and enhance processes, ensuring effective communicati...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Elevate your career by leading global product marketing initiatives, driving innovation from concept to commercialization while collaborating with cross-functional teams and engaging with key stakehol...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.