Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$123K - $136K *

Join a dynamic virtual medical team dedicated to transforming healthcare through evidence-based care. Collaborate with colleagues to provide exceptional telehealth services, ensuring patient-centered...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$123K - $136K *

Empower patients through virtual care by providing exceptional telehealth services. Collaborate with a dedicated team to deliver evidence-based medical support, ensuring quality care around the clock...

Boston, MARemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$145K - $165K *

Design and deliver AI solutions within clinical and product teams, spearheading validated features while ensuring compliance. Collaborate across functions to enhance AI fluency and operational capabil...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Drive clinical excellence by evaluating disability applications, guiding staff, and ensuring quality standards. Leverage expertise in medical records to make informed decisions and contribute to syste...

Reposted today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$130K - $222K *

Drive user-centered design for complex healthcare workflows, enhancing RCM experiences. Lead research and cross-functional collaboration, utilizing AI to refine solutions and improve usability from co...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$280K - $481K *

Join a team that's driving growth in advanced therapeutics through strategic leadership, P&L accountability, and innovative business development. Shape the future of RNA oligonucleotide manufacturing...

RemoteRemote

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Join us in shaping technical strategies and growth initiatives for federal opportunities. Collaborate across teams to develop compelling solutions that drive success in complex pursuits, ensuring alig...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Unlock potential by shaping innovative solutions for Opioid Treatment Programs and Medication Assisted Treatment. Collaborate with clients and teams to translate complex needs into actionable product...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$93K - $99K *

Play a key role in optimizing resident care by leading the MDS Assessment Process, developing individualized care plans, and ensuring compliance with regulations in a skilled nursing environment...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$261K - $346K *

Lead the charge in clinical pharmacology strategies for rare disease and oncology programs, driving innovative solutions, study designs, and regulatory interactions to expedite drug development and im...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $170K *

Shape the future of enterprise infrastructure by leading design, implementation, and optimization of systems. Drive automation, enhance security, and mentor junior staff while collaborating on strateg...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Join our team to provide individualized ABA therapy to children with autism. You'll design and oversee treatment plans, conduct assessments, and ensure progress through collaboration and mentorship in...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Empower children with tailored ABA therapy as a BCBA. Lead assessments, treatment design, and progress monitoring to enhance the skills of clients with autism and developmental disabilities in diverse...

Boston, MARemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$119K - $152K *

Join a team that's dedicated to providing comprehensive obesity care to adolescents and adults. Engage in a collaborative environment, empowering patients through evidence-based treatment while enjoyi...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$119K - $179K *

Lead the charge in architecting FHIR-compliant data models to enhance clinical data integration and usability, supporting patient care and research initiatives across the organization...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$87K - $104K *

Join a dynamic team as you balance high-quality imaging with clinical support in an urgent care setting, ensuring timely patient care while performing diagnostic radiology and assisting with various c...

Today

  •   Less than 5 years exp.  •   Healthcare

$87K - $104K *

Inspire your career by combining high-quality imaging with clinical support in a dynamic urgent care setting. Collaborate with providers and enhance patient care while performing diagnostic radiology...

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of cybersecurity in higher education by delivering expert assessments, advisory services, and tailored remediation plans that empower institutions to enhance their security posture an...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Shape the future of field service training by developing impactful materials and delivering hands-on instruction. Collaborate with engineers and customers to ensure compliance and enhance service qual...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $130K *

Drive innovative clinical trial strategies across US and EU for neurodegenerative diagnostics. Collaborate with cross-functional teams to ensure regulatory compliance and achieve key milestones in pro...

4 days ago

  •   Less than 5 years exp.  •   Business Services

$183K - $252K *

Optimize the US medical strategy for nephrology, driving execution and collaboration across teams to enhance patient outcomes through strategic insights, education, and KOL engagement in C3G and IC-MP...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$102K - $170K *

Lead the charge in full-stack development, collaborating on enterprise modernization with Microservices. Deliver high-quality software, mentor engineers, and ensure best practices for cloud technologi...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$180K - $240K *

Unlock potential by developing reinforcement learning policies for humanoid robots, ensuring seamless sim-to-real transfer, and integrating control techniques to achieve reliable, high-performance phy...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$270K - $280K *

Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a team that's dedicated to advancing drug candidates by serving as the key legal partner for clinical operations, driving critical agreement execution while ensuring compliance and safeguarding i...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.