Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$100K - $120K *

Join a dynamic IT team as the Clinical Systems Specialist, bridging Clinical Operations and Data Science to support and automate clinical systems, enhance data pipelines, and streamline operations for...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$86K - $130K *

Join a team that's dedicated to guiding patients through their care journey. As a Nurse Case Manager, you'll assess needs, coordinate care, and support transitions, ensuring optimal patient outcomes a...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$113K - $136K *

Champion the development of infants and toddlers by providing essential home-based services, collaborating with families and community providers to ensure comprehensive care and support for children's...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$80K - $121K *

Lead impactful training initiatives designed to empower customers globally. Utilize innovative methods and foster strong relationships to enhance learning experiences and drive success across diverse...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$183K - $252K *

Lead the charge in developing and executing the US Medical strategy for Rare Disease, collaborating with cross-functional teams to enhance patient outcomes and ensure alignment with global initiatives...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$195K - $215K *

Elevate your career by leading clinical contracts strategy to drive global trials. Collaborate with diverse teams, shape negotiation approaches, and ensure compliance while developing a high-performin...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$93K - $116K *

Oversee neurodiversity-affirming clinical programming, leading a team of behavior technicians to enhance the lives of children with developmental differences while enjoying flexible scheduling and gro...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$175K - $210K *

Lead the charge in driving enterprise growth within healthcare by building relationships with national and regional health plans. Own new logo acquisition and expansion, leveraging a robust support sy...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Join a supportive team delivering evidence-based psychotherapy to older adults. Enjoy flexible scheduling, comprehensive admin support, and opportunities for professional growth while making a meaning...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$194K - $266K *

Champion the future of clinical research by leading study oversight, ensuring participant safety, and driving high-quality execution across cross-functional teams in a dynamic environment focused on r...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$300K - $373K *

Shape the future of mental health care by providing personalized psychiatric services. Collaborate with a dedicated team, enjoy flexible scheduling, and access ongoing professional development while f...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Empower your career by joining a dynamic pediatric team focused on innovative care for complex medical needs. This role blends clinical excellence with leadership, enhancing patient access and operati...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$300K - $373K *

Unlock your potential as a psychiatrist, focusing on patient care while enjoying flexible scheduling, collaboration with a dedicated team, and access to ongoing learning opportunities in a supportive...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $373K *

Unlock your potential as a psychiatrist, focusing on patient care while enjoying flexible scheduling, collaboration with a dedicated team, and access to ongoing learning opportunities in a supportive...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $373K *

Join a team that's dedicated to providing exceptional psychiatric care. Collaborate with a multi-disciplinary team to conduct evaluations and manage medications, while enjoying flexible scheduling and...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $373K *

Transform your career by joining a collaborative team focused on patient care. Enjoy flexible scheduling, ongoing support, and opportunities for professional growth while integrating psychotherapy int...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $373K *

Lead the charge in delivering exceptional outpatient psychiatric care, collaborating with a dedicated team to personalize your practice. Enjoy flexible scheduling, ongoing support, and opportunities f...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$93K - $102K *

Join our team as a Respiratory Care Practitioner, providing essential therapy and diagnostic services to diverse patients. Contribute to patient care in a dynamic hospital environment while maintainin...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $140K *

Shape the future of public service by leading technology consulting projects that enhance operational efficiency and strategic goals for state and local agencies, ensuring compliance and delivering im...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$149K - $296K *

Join a dynamic team to lead and guide radiation therapy delivery, ensuring safety and effectiveness. Collaborate with healthcare professionals while engaging in clinical tasks, research, and quality a...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$149K - $296K *

Lead the delivery of safe radiation therapy by guiding physicists and healthcare professionals, ensuring quality assurance, and participating in innovative treatment development while managing clinica...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$99K - $232K *

Lead and inspire teams in provider clinical operations, driving modernization initiatives through strategic consulting, process improvement, and technology integration to enhance healthcare delivery a...

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$133K - $330K *

Grow your career with a patient-focused practice that offers diverse procedures in a supportive environment, outstanding earning potential, modern technology, and opportunities for continuous educatio...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $165K *

Champion your career by providing strategic legal counsel and risk management support. Collaborate with executive leadership to navigate complex legal matters, ensuring compliance and alignment with o...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Lead strategic business development initiatives, driving deal execution and relationship management with senior health plan stakeholders. Shape growth strategies and negotiate value-based care contrac...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.