Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$225K - $309K *

Lead the charge in developing and executing innovative medical strategies for Rare Diseases, collaborating across teams to enhance patient outcomes and align with global initiatives while nurturing ke...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$70K - $105K *

Join a team that's dedicated to enhancing the lives of older adults through personalized, one-on-one Occupational Therapy. Enjoy flexibility and autonomy while making a meaningful impact in diverse ca...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$185K *

Unlock potential by leading project teams and delivering actionable insights through research and analysis, while fostering client relationships and mentoring talent in a dynamic environment...

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $173K *

Join a team that's dedicated to delivering exceptional neurocritical care. Collaborate with a multidisciplinary team to assess, manage, and treat neurology and neurosurgery patients in a dynamic ICU e...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$280K - $360K *

Transform healthcare delivery by leading comprehensive medical services, ensuring high-quality, patient-centered care while managing a dedicated team in a dynamic environment. Drive initiatives that e...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$75K - $100K *

Shape the future of integrated behavioral health by joining our dynamic team. Collaborate with primary care professionals to deliver evidence-based therapies, enhancing patient care for adults facing...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $100K *

Shape the future of integrated behavioral health by providing exceptional care in a fast-paced environment, collaborating with medical teams to address diverse patient needs across the lifespan using...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$206K - $268K *

Lead the charge in advancing nephrology clinical programs through strategic design, execution, and analysis of clinical trials, ensuring compliance with Good Clinical Practices while collaborating wit...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$297K - $367K *

Grow your career with a pivotal role driving hospital data integration and compliance. Lead execution of clinical data operations, build relationships, and ensure secure data handling while shaping a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$116K - $137K *

Join a dynamic neurobiology team to advance neuroscience research through innovative in vivo and ex vivo studies. Collaborate across functions to validate targets and develop therapeutics for neuropsy...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $205K *

Join a dynamic team to lead AI agent deployments in healthcare. Leverage your software engineering expertise and client-facing skills to drive technical delivery, influence product development, and en...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $119K *

Collaborate to drive single-cell proteomics research on Alzheimer's and neurodegeneration. Design and execute experiments, analyze datasets, mentor junior scientists, and prepare manuscripts within an...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $115K *

Champion clinical excellence by leading and mentoring a dynamic ECM team, ensuring comprehensive patient care and adherence to individualized plans, while collaborating effectively with multidisciplin...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Collaborate to deliver high-quality primary care for seniors in various living communities, building meaningful patient relationships and enhancing well-being through expert care management and innova...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $145K *

Contribute to transformative behavioral therapy by delivering tailored interventions in clients' homes, enhancing communication and understanding for families. Join us in making a meaningful impact on...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $145K *

Deliver structured therapeutic interventions in clients' homes while empowering caregivers to enhance communication and understand their children's behavioral needs...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $107K *

Empower individuals by providing in-home speech therapy services to enhance communication and swallowing skills for older adults. Collaborate with interdisciplinary teams to deliver personalized care...

Massachusetts, USRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$350K - $430K *

Join a team that's at the forefront of ophthalmic genetic medicine development. Provide strategic oversight for clinical studies, ensuring patient safety and data integrity while collaborating with cr...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$75K - $100K *

Join a team that's dedicated to providing exceptional outpatient therapy services. Enjoy flexible scheduling with hybrid telehealth options, competitive compensation, and comprehensive support to enha...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$174K - $374K *

Unlock potential by leading medical management initiatives remotely, supporting member needs and optimizing clinical services for optimal care. Leverage your expertise in Orthopedic Spine or Neurosurg...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $110K *

Grow your career with a dynamic team dedicated to advancing medical education for early-career orthopedic surgeons through innovative learning experiences, collaboration, and strategic planning...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $110K *

Join a team that's dedicated to transforming mental health care with creativity and compassion. You'll assess client needs, implement treatment plans, and collaborate within a supportive environment...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $257K *

Join our dynamic team to provide exceptional mental health care through a hybrid model, combining telehealth and in-office support. Collaborate with dedicated professionals while enjoying flexible sch...

Today

  •   Less than 5 years exp.  •   Healthcare

$200K - $257K *

Transform patient care by providing comprehensive psychiatric evaluations and treatments. Work in a hybrid model, ensuring flexibility and accessibility to mental health services while collaborating w...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $257K *

Accelerate your career as a Psychiatric Mental Health Nurse Practitioner, delivering expert care to children and adolescents. Enjoy a hybrid work schedule and collaborative environment, while making a...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.