Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Configuration Professional II, Contact Center Solutions
$75K - $95K *
Unlock potential by managing Genesys Cloud configurations and ensuring system integrity. Collaborate with teams to implement changes, troubleshoot issues, and maintain documentation for optimal contac...
1 week ago
$80K - $95K *
Join a team that's dedicated to optimizing data-centric applications. As a Systems Applications Engineer, you'll ensure critical systems run smoothly, collaborating with stakeholders and mentoring jun...
2 weeks ago
Digital Communications Automation Specialist
$70K - $126K *
Drive impactful digital content development through Salesforce Marketing Cloud, managing cross-functional communication strategies to enhance member engagement and optimize performance metrics for eff...
4 days ago
Digital Communications Automation Specialist
$70K - $126K *
Transform member engagement by developing digital content through Salesforce Marketing Cloud. Collaborate across teams to manage communication strategies, analyze performance metrics, and enhance user...
4 days ago
Senior Director, BSS Engineering & Product
$240K - $318K *
Lead a global BSS engineering team, driving architecture, delivery, and product strategy while ensuring platform performance and compliance across diverse telecommunications solutions...
Reposted today
Sales Engineer (Pacific Coast)
$100K - $120K *
Transform the sales process by providing expert technical support and product demonstrations. Collaborate with internal teams to address customer needs and enhance training, ensuring a seamless experi...
3 weeks ago
$67K - $100K *
Drive operational excellence by supporting the development and maintenance of standardized playbooks, SOPs, and workflows. Collaborate with cross-functional teams to ensure clarity and consistency in...
1 week ago
$63K - $129K *
Transform security operations by automating ICAM workflows and enhancing Zero Trust policies. Collaborate with cross-functional teams to build secure, scalable solutions that strengthen enterprise sec...
Reposted 2 weeks ago
$124K - $170K *
Lead the charge in innovative software solutions for healthcare, collaborating with diverse teams to enhance patient care and meet customer needs through cutting-edge technology and creative problem-s...
2 weeks ago
$190K - $237K *
Unlock the potential of global communications by leading strategic initiatives that enhance brand visibility, media engagement, and corporate storytelling. Drive impactful narratives that position the...
1 week ago
Senior Cloud Infrastructure Engineer
$120K - $145K *
Empower innovation by leading the design of scalable Azure cloud solutions. Drive automation, mentor engineers, and leverage AI to enhance infrastructure reliability and operational efficiency while c...
Today
Senior Software Engineer - Open Source (RD217)
$148K - $201K *
Empower the development of our open source software solutions while collaborating with engineers and community contributors. Leverage your cloud native expertise to enhance mission outcomes through in...
Reposted 2 weeks ago
Product Manager, Provider Marketplace
$120K - $145K *
Join a dynamic team to drive the development of a cutting-edge marketplace, enhancing provider products and economic incentives while collaborating closely with engineering and operations to transform...
5 days ago
$90K - $110K *
Join a dynamic team to lead field control system commissioning and support for diverse facilities. Drive project success through technical expertise in PLC/DCS systems, ensuring safety and operational...
4 weeks ago
$90K - $110K *
Lead and execute field control system commissioning and troubleshooting for diverse facilities. Collaborate with teams to ensure safety and efficiency while producing documentation that meets project...
4 weeks ago
Power Engineer, Physical Electrical
$140K - $160K *
Join a dynamic team to execute complex physical electrical designs for medium- and high-voltage substations and utility-scale projects, ensuring quality and compliance from concept through constructio...
Reposted today
Account Executive (Enterprise)
$110K - $130K *
Champion the full sales cycle for top enterprise accounts, utilizing a consultative approach to solve complex challenges. Drive impactful relationships with stakeholders, and navigate lengthy processe...
Reposted 1 week ago
Senior Global Product Manager, Enabling Technologies
$120K - $145K *
Lead strategic product initiatives in advanced surgical technologies, driving development and commercialization efforts. Collaborate with cross-functional teams to enhance orthopedic outcomes and proc...
3 weeks ago
$100K - $120K *
Drive strategic initiatives to uncover and expand business opportunities, generating new sales through targeted contracts and executive-level relationships while mentoring sales teams and managing cus...
4 weeks ago
Intelligent Infrastructure Services Advisory Lead
$122K - $317K *
Drive large-scale tech transformations by advising senior executives on infrastructure strategies, leading engineering programs, and shaping modern, resilient infrastructure across diverse environment...
Reposted 1 week ago
Director, Public Sector Channels
$180K - $200K *
Join a dynamic team as a strategic leader to drive the public sector channel strategy, focusing on the U.S. federal market. Build relationships, execute go-to-market plans, and empower partners to del...
2 weeks ago
$150K - $180K *
Transform the infrastructure landscape by leading Site Reliability Engineering and platform architecture for global expansion, ensuring reliability, cost efficiency, and compliance across multiple ser...
1 week ago
$140K - $170K *
Elevate enterprise sales by leading full-cycle engagements with large insurance carriers, leveraging consultative selling and technical fluency to drive value through innovative solutions and strategi...
1 week ago
$150K - $180K *
Join a team that's redefining product marketing in cybersecurity. Lead a small team to craft compelling narratives, drive go-to-market strategies, and collaborate across functions to ensure product su...
1 week ago
$105K - $231K *
Accelerate progress at the forefront of SAP integration, driving complex data exchanges and ensuring compliance with DoD standards while enhancing transportation operations across diverse systems...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.