Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$112K - $179K *
Unlock innovative cloud solutions by designing and governing enterprise architectures on AWS and Azure. Collaborate with cross-functional teams to ensure compliance, optimize performance, and lead clo...
4 days ago
$170K - $240K *
Unlock potential by serving as a strategic technical advisor for key enterprise customers, guiding architecture decisions and aligning technical plans with business outcomes to ensure successful imple...
2 weeks ago
Senior Director, Data Architecture
$150K - $180K *
Champion enterprise data architecture by establishing standards and a unified data catalog. Collaborate across teams to define metrics and ensure data governance, driving alignment and clarity in a ha...
3 weeks ago
$95K - $115K *
Lead the charge in enhancing organizational security by developing security frameworks, assessing controls, and collaborating with technical teams to create a resilient security architecture for moder...
Reposted 5 days ago
$282K - $353K *
Transform the AI landscape by owning technical wins in enterprise deals, leveraging data architecture, and delivering superior AI solutions. Collaborate with executive teams to validate and design inn...
Reposted 5 days ago
$95K - $115K *
Drive network security innovation by developing and integrating robust software solutions. Collaborate with cross-functional teams to enhance security infrastructure and ensure seamless functionality...
4 days ago
Customer Success Engineer / Architect
$110K - $130K *
Drive customer success as a technical expert, partnering to optimize IoT deployments. Your strategic insights will enhance service adoption and expand account growth, delivering tangible business outc...
Reposted 4 weeks ago
Sr. Network Engineer, Managed Services
$115K - $165K *
Join our team to provide advanced support as a Senior Network Engineer, overseeing complex issues across multiple technologies and enhancing network performance for diverse client environments. Drive...
Reposted 3 days ago
$77K - $118K *
Drive the evolution of scalable, secure platforms by architecting solutions that enhance network intelligence and application delivery, collaborating with cross-functional teams to optimize performanc...
Reposted 1 week ago
Enterprise Integration Architect
$110K - $130K *
Contribute to the design and governance of enterprise integration solutions, ensuring seamless connectivity across applications and data services. Lead strategic initiatives, evaluate technologies, an...
3 weeks ago
$100K - $120K *
Join a dynamic team as a System Engineer, specializing in Linux systems and automation. You'll lead the design and maintenance of provisioning workflows, configuration management, and Linux networking...
Yesterday
Senior Solutions Architect (FedS063)
$125K - $150K *
Elevate customer experiences by leading a team of engineers, providing strategic insights, and implementing innovative solutions in growth engineering and digital marketing for impactful delivery serv...
3 weeks ago
Strategic Business Developer 5
$120K - $145K *
Shape the future of avionics sales by leading business development efforts, engaging military and commercial aerospace customers, and driving strategic growth in the Americas through innovative test s...
1 week ago
$110K - $140K *
Unlock the potential of our partner ecosystem by designing and delivering impactful enablement programs that elevate partner performance through engaging, high-quality training experiences...
Reposted 2 weeks ago
$145K - $175K *
Join us to define and drive the enterprise cloud database strategy, leading architecture and modernization efforts to create scalable, reliable solutions for healthcare applications serving millions o...
5 days ago
$135K - $160K *
Lead the charge in delivering innovative solutions as a Solutions Architect, guiding teams and customers through technical challenges while maximizing mission impact and enhancing customer experiences...
2 weeks ago
Principal Consultant - Education Cloud Architect
$125K - $150K *
Drive transformative Salesforce solutions in higher education as a trusted advisor. Lead architecture design, align technology with institutional goals, and ensure successful delivery of Education Clo...
3 weeks ago
$110K - $140K *
Transform infrastructure and deployment modernization efforts, serving as a technical cornerstone for multiple programs. Drive DevSecOps maturity and cloud adoption while ensuring secure, rapid delive...
5 days ago
Principal GTM Systems Architect
$200K - $220K *
Lead the design and implementation of advanced systems and workflows for GTM teams. Drive technical initiatives to optimize scalability, leverage AI, and mentor engineers, ensuring robust architectura...
Reposted 2 weeks ago
$135K - $150K *
Join a team that's engineering innovative cloud solutions, ensuring stability and performance while driving continuous improvement across scalable environments. Your expertise will shape the future of...
2 weeks ago
$89K - $155K *
Lead the design and implementation of a UiPath automation program, establishing governance and operational standards while collaborating with a diverse team to build a Center of Excellence from the gr...
2 weeks ago
$127K - $212K *
Champion secure architecture by conducting reviews and assessments for cloud and on-premise systems. Leverage your cybersecurity expertise to design solutions that align with security best practices a...
1 week ago
Software Architect / Technical Advisor
$120K - $145K *
Contribute to architectural guidance and technical support across diverse projects. Collaborate with teams to evaluate solutions, adapt to evolving technologies, and communicate findings effectively t...
Today
Fellow Digital Technology Architect Operations - Remote
$206K - $267K *
Transform your career by leading innovative architectural strategies and governance. As a trusted advisor, you will drive technology alignment and maximize investments while mentoring cross-functional...
Reposted 2 weeks ago
$120K - $145K *
Accelerate your career by designing and optimizing secure, scalable cloud infrastructure. Collaborate with cross-functional teams to enhance operational efficiency and ensure high availability for glo...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.