Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Software Engineer, DevOps
$119K - $167K *
Lead the charge in evolving our cloud infrastructure and CI/CD systems. As a Senior DevOps Engineer, you'll enhance security, reliability, and operational efficiency while mentoring a team and ensurin...
Reposted 5 days ago
ServiceNow Mid-Level Developer
$130K - $150K *
Lead the charge in designing and implementing HR Service Delivery solutions, integrating Microsoft 365 with ServiceNow. Optimize employee experiences through automated workflows and seamless connectio...
5 days ago
ServiceNow Mid-Level Developer
$130K - $150K *
Elevate employee experiences by designing and implementing HR solutions. Lead technical projects, optimize integrations with Microsoft 365, and mentor developers to enhance ServiceNow capabilities and...
1 week ago
$125K - $150K *
Elevate your career by driving data engineering excellence in Palantir Foundry, transforming legacy systems into robust pipelines and applications while collaborating with cross-functional teams to de...
3 weeks ago
DESIGN MANAGER - DESIGN BUILD HIGHWAY/ MANAGED LANES
$262K - $419K *
Help us elevate infrastructure projects by leading design teams on mega initiatives. This role demands extensive experience in managing complex highway projects, ensuring quality delivery on time and...
4 weeks ago
$160K - $180K *
Collaborate with partners to build a robust technical foundation for channel sales. Enable engineers to independently deploy solutions, ensuring technical readiness and driving measurable success in p...
1 week ago
Senior Director, Business Development
$150K - $180K *
Join a team that's driving growth in the biopharmaceutical sector by developing strategic business relationships, prospecting new clients, and leading sales initiatives to achieve organizational objec...
1 week ago
Principal Solutions Consultant, Google Cloud + Gemini
$180K *
Optimize cloud strategies for partners by transforming Google Cloud and AI opportunities into sustainable workloads, guiding technical and commercial discussions, and fostering repeatable practices fo...
4 days ago
$72K - $94K *
Contribute to program success by planning, coordinating, and executing activities. Collaborate with teams and stakeholders to monitor progress, manage risks, and analyze data, ensuring objectives are...
4 days ago
$232K - $320K *
Unlock potential by leading a dynamic Solutions Consulting team to deliver innovative cybersecurity solutions. Collaborate with sales and customers to ensure value realization and drive success in pre...
4 days ago
Department Manager: Physical Design Engineer
$174K - $296K *
Champion the growth of a substation engineering practice by leading a diverse team, driving operational excellence, and delivering innovative solutions for utility clients nationwide while ensuring te...
Reposted 4 weeks ago
$95K - $115K *
Transform the ScriptMed Cloud Platform by designing and deploying scalable solutions. Collaborate with teams to automate workflows and enhance customer onboarding while ensuring compliance with data s...
5 days ago
Sr. Subcontract Administrator (Remote)
$88K - $154K *
Transform subcontracting processes by managing proposals, contracts, and vendor relationships. Leverage your expertise to ensure compliance and efficiency while guiding a team in a dynamic, remote env...
2 weeks ago
$75K - $158K *
Transform business objectives into actionable insights by leveraging Agile methodologies. Collaborate with cross-functional teams to refine backlogs, create user stories, and ensure alignment between...
2 days ago
$75K - $158K *
Empower cross-functional teams as a Business Analyst, driving Agile practices, refining backlogs, and aligning business objectives with technical execution to enhance project outcomes and stakeholder...
Reposted 2 weeks ago
$91K - $163K *
Lead the charge in safeguarding our organization against evolving cyber threats. As a Senior Cybersecurity Engineer, you'll design robust defenses and collaborate across teams to enhance security post...
2 weeks ago
Project Mgr, Strategic Initiatives
$80K - $95K *
Lead cross-functional projects in health plan relations, enhancing revenue cycle performance and outcomes. Utilize strong communication and project management skills to coordinate initiatives, track p...
Reposted 6 days ago
$120K - $150K *
Unlock potential by driving AI deployment strategies with clients, translating business needs into actionable use cases, and ensuring successful model adoption. Collaborate closely with engineers and...
1 week ago
SAP Tech Director Generalist ( S/4 Migration, Appdev,integration, brown/blue, RISE+ AI)
$155K - $410K *
Advance SAP technology initiatives by leading S/4 migrations, application development, and cloud transformations. Drive strategic direction, mentor teams, and enhance client relationships to improve o...
Yesterday
Manufacturing Quality Engineer, Data Center Equipment
$110K - $130K *
Transform the quality landscape of data center equipment by overseeing supplier audits, inspections, and continuous improvement initiatives. Collaborate with cross-functional teams to ensure complianc...
3 days ago
Software Engineer III - Full Stack (Drupal)
$105K - $110K *
Drive innovation as a Software Engineer III, enhancing full-stack capabilities and mentoring junior developers while collaborating with stakeholders to improve engineering processes and deliver impact...
Reposted 6 days ago
Delivery Manager - Decypher Corporate
$135K - $150K *
Unlock potential by overseeing project operations and client relationships, driving growth through strategic partnerships and best practices. Lead teams to achieve business goals while ensuring high s...
1 week ago
Director, Strategic Initiatives
$149K - $205K *
Elevate innovation at the forefront of foodtech, agritech, and infrastructure. Lead strategic initiatives, build ecosystems, and drive new ventures to shape the future landscape of Mitsubishi Electric...
1 week ago
$95K - $115K *
Join a team that's driving innovation in healthcare solutions by collaborating with sales to design and communicate technical solutions that meet customer needs, ensuring alignment with company capabi...
Yesterday
$180K - $200K *
Unlock growth by leading strategic customer relationships, driving innovative solutions, and enhancing partnerships. Collaborate across teams to deliver exceptional experiences and maximize revenue in...
Yesterday
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.