Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Linux Development Engineer – eLxr Distribution
$110K - $130K *
Join a team that's shaping the future of Linux development by enhancing a Debian-based distribution. Collaborate with cross-functional teams to deliver reliable platform capabilities for mission-criti...
3 weeks ago
Senior Full-Stack Engineer (AI-Native)
$110K - $130K *
Optimize end-to-end project delivery by developing customer-facing products and internal tools. Collaborate with stakeholders to rapidly turn needs into functional solutions, leveraging AI and modern...
3 weeks ago
Deputy PM - Construction Manager, Senior
$125K - $225K *
Oversee complex industrial construction projects, ensuring safety, quality, and timely completion. Lead multidisciplinary teams, manage contractor performance, and coordinate with stakeholders to achi...
1 week ago
Project Engineer (Engineering & Construction) - Data Center
$80K - $95K *
Join a team that's dedicated to enhancing building systems through innovative engineering solutions. Support project lifecycles from design to execution, ensuring quality and efficiency in electrical...
2 weeks ago
Digital Solutions Integration Engineer III
$110K - $130K *
Join a dynamic team to design and support advanced Active Network Management Systems, leading their lifecycle from development to commissioning while ensuring integration with external systems and del...
1 week ago
Solutions Engineer - Agents & Automation
$150K - $200K *
Unlock potential by driving enterprise agent solutions with Microsoft technologies. Collaborate on agent governance, lifecycle management, and secure operations, while translating designs into product...
1 week ago
$68K - $113K *
Lead project coordination efforts by ensuring effective communication and management of materials, schedules, and documentation. Collaborate with teams to streamline processes and enhance project effi...
Reposted 6 days ago
AI First iOS Software Engineer (Remote)
$85K - $125K *
Accelerate progress at the forefront of mobile development by leveraging AI tools to enhance iOS applications. Collaborate with cross-functional teams to deliver high-quality, customer-centric marketp...
3 weeks ago
$80K - $95K *
Tackle critical cybersecurity challenges as an Information Assurance Analyst, ensuring compliance and security for key Army systems. Collaborate with technical teams to conduct vulnerability assessmen...
4 days ago
Senior Fire Protection Engineer
$95K - $115K *
Transform safety standards by leading fire protection system designs for diverse facilities. Collaborate with multidisciplinary teams to deliver innovative, compliant solutions that ensure reliability...
Reposted 2 weeks ago
Senior Manager, Deployed Engineering
$150K - $180K *
Pioneer innovative solutions as a Senior Manager in Deployed Engineering, leading hands-on deployments and building a high-performing team. Collaborate closely with customers and internal teams to dri...
3 weeks ago
Technical Account Manager, Commercial
$130K - $160K *
Join a team that's dedicated to optimizing customer success through technical expertise. As a trusted advisor, you'll manage relationships, guide deployments, and ensure seamless adoption for federal...
Reposted today
$95K - $115K *
Drive procurement excellence by managing contracts and costs for large-scale projects. Leverage your expertise in construction management to ensure compliance, optimize processes, and foster collabora...
2 weeks ago
$110K - $130K *
Champion growth by driving enterprise sales in cybersecurity. Collaborate with cross-functional teams to build strategies, manage complex sales cycles, and establish long-term partnerships with key st...
1 week ago
Project Manager - Institutional
$95K - $115K *
Lead the charge in delivering complex healthcare construction projects, ensuring safety, budget adherence, and compliance. Collaborate with multidisciplinary teams to enhance patient care while managi...
Reposted today
Technical Recruiter (Remote United States)
$85K - $105K *
Lead strategic recruitment efforts for engineering and architecture roles, partnering with hiring managers to cultivate talent pipelines and engage passive candidates through innovative sourcing techn...
Reposted 2 weeks ago
Enterprise Account Manager, State and Local Government
$148K - $235K *
Join a team that's advancing public-sector innovation through AI and technology. Drive strategic relationships and sales growth across state and local government while addressing complex service and o...
Reposted 2 weeks ago
Architectural Specialties (AS) Estimating Supervisor Job
$85K - $100K *
Join a team that's leading a high-impact estimating department, driving operational excellence and cross-functional collaboration. Oversee daily activities, mentor team members, and enhance pricing st...
Reposted today
Business Systems Analyst - ERP/MES
$80K - $95K *
Empower your career by supporting business applications and enhancing systems. Collaborate with cross-functional teams to ensure reliability and continuous improvement in manufacturing processes and d...
6 days ago
$110K - $130K *
Champion growth in the retail sector by driving account development and sales. Leverage strong customer relationships to enhance satisfaction and profitability while effectively managing your sales pi...
Reposted 2 weeks ago
$80K - $95K *
Lead the end-to-end recruiting process, enhancing strategies and partnerships across departments. Drive high-volume hiring with autonomy, ensuring a seamless candidate experience while collaborating c...
1 week ago
Senior Security Consultant, Red Team
$75K - $150K *
Elevate cybersecurity effectiveness by leading proactive Red Team operations that simulate real-world threats, from social engineering to physical security testing, ensuring clients are resilient agai...
Reposted 4 weeks ago
$221K - $260K *
Lead the execution of multi-facility clean energy campuses, overseeing complex solar, wind, and battery projects. Collaborate with diverse teams to ensure operational excellence and strategic alignmen...
2 weeks ago
$75K - $158K *
Drive agile excellence by coaching teams in a scaled framework, facilitating planning, and enhancing collaboration. Engage with stakeholders to ensure successful delivery and continuous improvement in...
5 days ago
$88K - $105K *
Contribute to the successful execution of design-build projects in Life Sciences, overseeing all phases from design to closeout while mentoring junior staff and ensuring quality and timely delivery...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.